Preparation method of microcapsules composited by evening primrose oil and rosehip oil

A technology of composite microcapsules and rosehip oil, which is applied in the field of preparation of vegetable oil microcapsules, can solve the problems of serious agglomeration, low embedding rate, and low degree of dispersion, and achieve high oxidation stability, easy digestion and absorption, The effect of simple production process

Inactive Publication Date: 2015-12-23
JILIN PROVINCE SCI & TECH EVALUATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the embedding effect of natural polymer materials in the prior art is better, the embedding rate is low with the increase of drug loading.
And the current evening primrose oil and rosehip oil microcapsule techn

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0029] Example 1

[0030] (1) Preparation of the core material: 20 parts by mass of rosehip oil, 8 parts by mass of lecithin, and vacuum melting with a stainless steel colloid mill. After 15 minutes, 72 parts by mass of evening primrose oil were added to continue stirring and melting for 50 minutes;

[0031] (2) Preparation of wall material liquid: use 65 parts by mass of cyclodextrin, 30 parts by mass of gum arabic, and 5 parts by mass of sucrose as wall material, add it to the batching tank at room temperature, and add purified water to make a solid content of 43% Wall material liquid.

[0032] (3) Emulsification: After the wall material liquid is cooled to 50°C, it is mixed with the core material prepared in step (1). The ratio of the core material to the quality wall material is 1.7:1. Stir for 15 minutes to make it fully mixed Evenly, mixed into an emulsion with a solid content of 45%.

[0033] (4) High-pressure homogenization: homogenize the emulsion obtained in step (3) with a...

Example Embodiment

[0037] Example 2

[0038] (1) Preparation of the core material: 20 parts by mass of rosehip oil, 8 parts by mass of lecithin, and vacuum melting with a stainless steel colloid mill. After 15 minutes, 72 parts by mass of evening primrose oil were added to continue stirring and melting for 50 minutes.

[0039] (2) Preparation of wall material liquid: use 70 parts by mass of cyclodextrin, 20 parts by mass of gum arabic, and 10 parts by mass of sucrose as wall material, add it to the batching tank at room temperature, and add purified water to make a solid content of 40% Wall material liquid.

[0040] (3) Emulsification: After cooling the wall material liquid to 50℃, mix it with the core material made in step (1), where the mass ratio of the core material to the wall material liquid is 1.7:1, stir for 15 minutes to make it fully mixed, and mix Emulsion with a solid content of 49.5%.

[0041] (4) High-pressure homogenization: The emulsion obtained in step (3) is homogenized twice with a h...

Example Embodiment

[0044] Example 3

[0045] (1) Preparation of the core material: 20 parts by mass of rosehip oil, 8 parts by mass of lecithin, and vacuum melting with a stainless steel colloid mill. After 15 minutes, 72 parts by mass of evening primrose oil were added to continue stirring and melting for 50 minutes;

[0046] (2) Preparation of wall material liquid: use 60 parts by mass of cyclodextrin, 20 parts by mass of gum arabic, and 5 parts by mass of sucrose as wall material, add it to the batching tank at room temperature, and add purified water to make a solid content of 43% Wall material liquid.

[0047] (3) Emulsification: After cooling the wall material liquid to 50°C, mix it with the core material prepared in step (1), where the mass ratio of the core material to the wall material liquid is 1.7:1, stir for 15 minutes to make it fully mixed, and mix Emulsion with 30% solid content.

[0048] (4) High-pressure homogenization: The emulsion obtained in step (3) is homogenized twice with a high...

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Abstract

The invention discloses a preparation method of microcapsules composited by evening primrose oil and rosehip oil. The preparation method comprises the steps of picking the evening primrose oil, the rosehip oil and lecithin, conducting vacuum melting, and treating the ingredients as core materials; picking cyclodextrin, Arabic gum and cane sugar, conducting hydration with water, and treating the ingredients as liquid wall materials; mixing the core materials with the liquid wall materials, conducting sufficient emulsification, and obtaining emulsion; making the emulsion be subjected to spray freeze-drying, and obtaining the microcapsules composited by the evening primrose oil and the rosehip oil. According to the preparation method, the spray freeze-drying method is adopted, the drying rate is high, the drying time is short, the production process is simple and flexible, the operation and control are convenient to conduct, and the preparation method is suitable for mass production. The prepared microcapsules are high in oil content, loss of gamma-linolenic acid is reduced to the greatest extent, and oxidative deterioration is not prone to occurring; the microcapsules are good in taste, easy to digest and absorb and high in biological value of functional components; the microcapsules can be eaten directly and can also be prepared into drugs, health products, food additives and cosmetics.

Description

technical field [0001] The invention relates to a preparation method of vegetable oil microcapsules. More specifically, it relates to a preparation method of evening primrose oil and rosehip oil composite microcapsules. Background technique [0002] Main ingredients of evening primrose oil: r-linolenic acid, magnesium, zinc, copper, vitamin C, E, B6, B5. Containing 70-80% linoleic acid, especially the rare gamma-linolenic acid with special physiological activity, has many therapeutic functions, and is internationally recognized as having the functions of lowering cholesterol, preventing arteriosclerosis, beautifying, losing weight, anti-inflammation, and relieving Schizophrenia, anti-cancer and anti-aging effects. Ingredients of rosehip oil: γ-linolenic acid, unsaturated fatty acid, palmitic acid, citric acid, vitamin A, C, carotenoids, edible can anti-aging, effective for arthritis, high blood pressure and high cholesterol, soft skin , Whitening effect. In recent years,...

Claims

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Application Information

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IPC IPC(8): A23D9/04A61K8/92A61K36/738A61K9/50A61K8/11
Inventor 张强张鹏齐丽娜
Owner JILIN PROVINCE SCI & TECH EVALUATION
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