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A kind of micronano scale fish oil/algae oil microcapsule and its preparation process

A microcapsule and micro-nano technology, applied in the field of food processing, can solve the problems of large size, from tens of microns to hundreds of microns, high production cost, uneven particle size, etc., to improve acceptability and production cost Low, good coverage effect

Active Publication Date: 2019-01-29
NAT INST FOR NUTRITION & HEALTH CHINESE CENT FOR DISEASE CONTROL & PREVENTION +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The fish oil / algae oil microencapsulation products on the existing market are mainly produced by traditional spray drying technology. The microcapsules prepared by this process mainly have the following shortcomings: First, the size of the microcapsules is generally large, ranging from tens of microns or even to Hundreds of microns, and the particle size is not uniform, which limits its effective absorption on the intestinal mucosa to a certain extent; secondly, the inherent high temperature in the spray drying process will make the polyunsaturated fatty acids in fish oil / algae oil Partially degrades, resulting in reduced nutritional value of the product
Patent application number 201310590455.9 discloses a preparation method of fish oil nano-liposomes, and obtains fish oil microcapsules with uniform particle size and nano-scale. However, the production cost of liposome technology itself is very high, which is not suitable for large-scale promotion and application

Method used

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  • A kind of micronano scale fish oil/algae oil microcapsule and its preparation process
  • A kind of micronano scale fish oil/algae oil microcapsule and its preparation process
  • A kind of micronano scale fish oil/algae oil microcapsule and its preparation process

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Embodiment 1

[0022] (1) Preparation of internal oil phase: weigh 0.5g vitamin E, add it to 100mL deep-sea fish oil / algae oil, and stir magnetically for 1 hour;

[0023] (2) Water phase preparation: Weigh 0.2 g of sucrose fatty acid ester (SE-15), add it to 100 mL of 1.5% sodium alginate aqueous solution by mass ratio, and stir magnetically for 2 h;

[0024] (3) Preparation of external oil phase: Weigh an appropriate amount of 1g polyglycerol fatty acid ester (PO-5S), add it to 100mL sunflower oil, and stir magnetically for 1h;

[0025](4) Preparation of calcium chloride curing agent: add 5 mL of calcium chloride aqueous solution with a mass ratio of 5% to 15 mL of the outer oil phase of step (3), and ultrasonically emulsify for 2 min under the condition that the power is set to 30%;

[0026] (5) preparation of chitosan solution: 1.5g chitosan is added in the acetic acid solution of 100mLpH4.0, centrifuge after magnetic stirring 2h and take supernatant for subsequent use;

[0027] (6) The ...

Embodiment 2

[0034] (1) Preparation of internal oil phase: Weigh 0.1 g of fat-soluble ascorbic acid, add it to 100 mL of deep-sea fish oil / algae oil, and stir magnetically for 1 h;

[0035] (2) Preparation of aqueous phase: Weigh 0.1 g of Tween-20, add it to 100 mL of 1.0% sodium alginate aqueous solution by mass ratio, and stir magnetically for 2 h;

[0036] (3) Preparation of external oil phase: Weigh an appropriate amount of 2g of Span-80, add it to 100mL of sunflower oil, and stir for 1 hour with magnetic force;

[0037] (4) Preparation of calcium chloride curing agent: 5ml of calcium chloride aqueous solution with a mass ratio of 6% was added to 40mL of the outer oil phase of step (3), and ultrasonic emulsification was carried out for 2min at a set power of 30%;

[0038] (5) Preparation of chitosan solution: add 1.0 g chitosan to 100 mL of acetic acid solution at pH 4.0, centrifuge after magnetic stirring for 2 h to get the supernatant for subsequent use;

[0039] (6) The first rapid...

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Abstract

The present invention relates to a fish oil / algal oil microencapsulated product rich in polyunsaturated fatty acids (PUFA) essential to the human body and a production process thereof. The microcapsule is prepared by means of a premix membrane emulsification process and a complex coacervation method using sodium alginate and chitosan which are biodegradable, have health-care functions and are cheap and readily available as wall materials. The prepared fish oil / algal oil microcapsule is uniform in particle size, and the particle size can be controlled at hundreds of nanometers-tens of microns. The prepared fish oil / algal oil microcapsule has the advantages of good sustained release and enteric digestion effects, high absorption efficiency, low production cost, etc., and can be widely applied to food nutrition enhancement and health-care food.

Description

technical field [0001] The invention relates to microencapsulation technology in the field of food processing, in particular to a fish oil / algae oil microcapsule product and a preparation process thereof. Background technique [0002] Deep sea fish oil / algae oil is rich in polyunsaturated fatty acids (PUFA) which are essential for human body. In the PUFA family, docosahexaenoic acid (DHA) of the n-3 series and arachidonic acid (ARA) of the n-6 series are two very important PUFAs, and their concentrations are very high in nerve tissues, such as in Both PUFAs are involved in brain development and function, both in retinal photoreceptor cells and in the gray matter of the brain. Of these, DHA is essential for neurological and visual development, while ARA is critical for normal development and proper use of the vascular system. In addition, prostaglandin (PG), a metabolite of PUFA, also plays a crucial role in brain development. Expression of PG and its receptors is accelera...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/50A23L33/00A23P10/30
Inventor 霍军生王连艳黄建杨婷媛张贵锋刘辉张博
Owner NAT INST FOR NUTRITION & HEALTH CHINESE CENT FOR DISEASE CONTROL & PREVENTION
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