Rhizoma coptidis piece processing and comprehensive utilizing method

A processing method, the technology of Coptis chinensis tablets, is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, plant raw materials, etc., and can solve the problems of manual labor, large loss of alkaloids, and easy "slagging" to achieve automation and saving Energy, the effect of avoiding loss

Inactive Publication Date: 2016-06-15
SOUTHWEST UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main problems of the traditional Coptis chinensis production process: ①, Coptis chinensis is dried twice, energy consumption is very high; ②, when Coptis chinensis is soaked in water again, because the active ingredient of Coptis chinensis Coptidis alkaloids is water-soluble components, it will inevitably lead to the loss of active ingredients. Therefore, the alkaloid content of the decoction pieces obtained by traditional techniques is about 10% lower than that of Tonglian ("Chinese Pharmacopoeia" 2010 edition); ③. It is easy to "drop slag" (fragments), and the yield of Coptis chinensis is low. If the watering time is too long, the loss of alkaloids will be greater; ④, during the drying process of Coptis chinensis, cracks will appear in the internal dehydration, and the cracks will appear when slicing after watering again Will not close, resulting in cracks in the middle of Coptis chinensis, and the color deepens, affecting the appearance
The main disadvantages of this process are: ①. Before the raw material of Coptis chinensis is dried, the fibrous root is "soft" and cannot "knock off" the fibrous root, so it must be dried; "Through", there is a pair of contradictions, care about one and lose the oth

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 10 kilograms of fresh Coptis Rhizoma Coptis (that is, "maotuozi", composed of Coptis, fibrous roots, petioles, and sediment) from which the leaves of Coptis Rhizoma are cut off. Vibration is used to remove part of the mud and sand to obtain a crude Coptis Rhizoma fresh product; The clean product is dried in the shade at 10°C until the moisture content of Coptidis is 80%; then purified, the partially dehydrated Coptidis is fully vibrated with a vibrating screen to further remove the remaining sediment and roots; the purified Coptidis is cut by a decoction machine Cut into 0.1mm flakes and dry at 200°C until the water content of the flakes is 15%; use a 50-mesh sieve to separate the pieces of coptis and fibrous roots to obtain 1.25 kg of coptis.

[0020] High performance liquid chromatography (HPLC) was used to analyze the huanglian decoction pieces produced by this method and the traditional huanglian decoction pieces. The alkaloid content of the huanglian decoction pieces p...

Embodiment 2

[0022] 10 kilograms of fresh Coptis Rhizoma Coptis (that is, "maotuozi", composed of Coptis, fibrous roots, petioles and silt etc.) from which the leaves of Coptis chinensis have been cut off, washed with water to remove the sediment to obtain a crude fresh Coptis Rhizoma fresh product; Dry at 400℃ until the moisture content of Coptis 15%; Partially dehydrated Coptis is fully vibrated with a vibrating screen to further remove the remaining fibrous roots; After purification, Coptis is cut into 5mm slices using a decoction machine and dried at 20℃ , Until the water content of the slices is 5%; use a 2-mesh sieve to separate the pieces of coptis and fibrous roots and other scraps to obtain 1.35 kg of coptis.

[0023] High performance liquid chromatography (HPLC) was used to analyze Huanglian decoction pieces produced by this method and traditional Huanglian decoction pieces. The alkaloid content of Huanglian decoction pieces produced by this method was 13% higher than that of traditi...

Embodiment 3

[0025] 10 kilograms of fresh Coptis Rhizoma Coptidis leaves (ie, "Maotuozi", composed of Coptis chinensis, fibrous roots, petioles and silt, etc.) cut off the leaves of Coptis Rhizoma. Vibrate to remove part of the silt to obtain a crude Coptis Rhizoma fresh product; The product is dried at 100°C until the moisture content of Coptidis is 50%; the partially dehydrated Coptidis is fully vibrated with a vibrating screen to further remove the remaining sediment and fibrous roots; the purified Coptidis is cut into 1mm pieces by a decoction machine. Dry at 100°C until the water content of the flakes is 10%; use a 20-mesh sieve to separate the pieces of Coptis and fibrous roots and other scraps to obtain 1.55 kg of pieces of Coptis.

[0026] High performance liquid chromatography (HPLC) was used to analyze Huanglian decoction pieces produced by this method and traditional Huanglian decoction pieces. The alkaloid content of Huanglian decoction pieces produced by this method was 14% higher...

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PUM

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Abstract

The invention belongs to the technical field of traditional Chinese medicine processing and particularly relates to a rhizoma coptidis piece processing method. Mainly a new choice is provided for rhizoma coptidis piece processing. The method includes the following steps of harvesting, crude cleansing, dewatering, refined cleansing, slicing, drying and screening, and rhizoma coptidis decoction pieces are obtained, and leftovers obtained during cutting of the rhizoma coptidis pieces are comprehensively utilized. The method can be used for processing rhizoma coptidis pieces and rhizoma coptidis on the producing area, the method is high in industrialization degree, energy is saved, and the content of total alkaloids in the obtained rhizoma coptidis decoction pieces is higher than that of total alkaloids in rhizoma coptidis decoction pieces obtained through a traditional method by 10% or above.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine processing, and in particular relates to the production and comprehensive utilization technology of Coptis chinensis tablets. Background technique [0002] Coptis chinensis is bitter in taste, cold in nature, and has the functions of purging fire, detoxifying, clearing away heat, and drying dampness. For dysphoria, confusion, upset and insomnia, hot and humid fullness, vomiting, abdominal pain and diarrhea, conjunctival congestion and swelling, sore tongue, eczema, burns, vomiting blood, epistaxis, etc. Coptis chinensis was first recorded in "Shen Nong's Materia Medica", which clearly stated that the efficacy of Coptidis chinensis is "improving eyesight, clearing the intestines" and treating "abdominal pain, diarrhea" and gynecological diseases. Since "Shen Nong's Materia Medica", Chinese medicine monographs of all dynasties have specialized discussions: In the late Eastern H...

Claims

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Application Information

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IPC IPC(8): A61K36/718
CPCA61K36/718A61K2236/13A61K2236/15A61K2236/17
Inventor 李学刚叶小利李滟临
Owner SOUTHWEST UNIVERSITY
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