Black barbary wolfberry fruit procyanidine chewable tablets and preparation method thereof

A technology of proanthocyanidins and black wolfberry, which is applied in the field of preparation of black wolfberry proanthocyanidins chewable tablets, can solve the problems of producing black wolfberry proanthocyanidins chewable tablets, etc., achieve obvious health care functions, wide practicability, and increase the effect of PGE2 content

Inactive Publication Date: 2016-08-03
XINJIANG YUANSEN KANGLE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is currently no application for the production of chewable tablets specifically for black wolfberry proanthocyanidins, which has extensive practical significance for the development of black wolfberry proanthocyanidins chewable tablets

Method used

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  • Black barbary wolfberry fruit procyanidine chewable tablets and preparation method thereof
  • Black barbary wolfberry fruit procyanidine chewable tablets and preparation method thereof
  • Black barbary wolfberry fruit procyanidine chewable tablets and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1: Black wolfberry proanthocyanidins chewable tablets

[0030] In terms of weight percentage, the black wolfberry proanthocyanidin chewable tablet contains 3-5% black wolfberry proanthocyanidin, 20-40% black wolfberry powder, 20-50% milk powder, 0.5-2% lubricant, 10-15% binder and sweetness agent 15-20%.

[0031] The lubricant used in the present invention is preferably magnesium stearate, which has good fluidity and compressibility.

[0032] The adhesive used in the present invention is preferably MCC. The present invention has carried out pre-experiments by studying Starchl500, MCC, isomaltooligosaccharides, and maltodextrin. The results show that MCC has no peculiar smell in mouthfeel and has a good bonding effect.

[0033] The sweetener used in the present invention is preferably xylitol, the sweetness is easier to be accepted by consumers, and the sugar alcohol also has the advantages of low calorie value and caries prevention.

Embodiment 2

[0034] Example 2: Preparation of black wolfberry proanthocyanidins chewable tablets

[0035] Dry and crush black wolfberry at 50°C, add 8 times the amount of petroleum ether to soak for 24 hours to degrease, filter and recover petroleum ether, dry black wolfberry powder, add 61% ethanol solution at a solid-to-liquid ratio of 1:19 by weight Reflux extraction, the extraction temperature is 47°C, after several times of reflux and suction filtration, the filtrates are combined, cooled to room temperature, left to stand for 24 hours, and centrifugally filtered to obtain a clarified filtrate, which is added to the treated AB-8 at a flow rate of 1BV / h In a macroporous resin column, wash with water until the effluent is clear, elute with 6BV60% ethanol at a flow rate of 1BV / h, collect the eluate, concentrate under reduced pressure to a thick paste, and freeze-dry to obtain black wolfberry proanthocyanidin powder. The prepared wolfberry Proanthocyanidin powder 3g, black wolfberry powde...

Embodiment 3

[0036] Example 3: Preparation of black wolfberry proanthocyanidin chewable tablets

[0037]Dry and crush black wolfberry at 50°C, add 8 times the amount of petroleum ether to soak for 24 hours to degrease, filter and recover petroleum ether, dry black wolfberry powder, add 61% ethanol solution at a solid-to-liquid ratio of 1:19 by weight Reflux extraction, the extraction temperature is 47°C, after several times of reflux and suction filtration, the filtrates are combined, cooled to room temperature, left to stand for 24 hours, and centrifugally filtered to obtain a clarified filtrate, which is added to the treated AB-8 at a flow rate of 1BV / h In a macroporous resin column, wash with water until the effluent is clear, elute with 6BV60% ethanol at a flow rate of 1BV / h, collect the eluate, concentrate under reduced pressure to a thick paste, and freeze-dry to obtain black wolfberry proanthocyanidin powder. The prepared wolfberry Proanthocyanidin powder 5g, black wolfberry powder ...

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PUM

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Abstract

The invention discloses a preparation method of black barbary wolfberry fruit procyanidine chewable tablets .The procyanidine chewable tablets are prepared from, by mass, 3%-5% of black barbary wolfberry fruit procyanidine, 30%-40% of black barbary wolfberry fruit powder, 40%-50% of milk powder, 1%-2% of a lubricating agent, 10%-15% of a binding agent and 15%-20% of a sweetening agent .The invention further provides an extracting preparation technology of the black barbary wolfberry fruit procyanidine .The extracting preparation technology comprises the steps that the black barbary wolfberry fruit powder is added into a 61% ethanol solution according to the solid-to-liquid ratio of 1:19, and reflux extraction is conducted at 47 DEG C .The black barbary wolfberry fruit procyanidine chewable tablets prepared by taking the black barbary wolfberry fruit procyanidine as a pure natural additive have the very good oxidation resistance, are high in absorptivity and nutritive value and beneficial for improving the human body immunity and the like and have the certain healthcare function; in addition, the chewable tablets are easy to transport and store, therefore, more people can obtain nutrition of the black barbary wolfberry fruit procyanidine, and the high practicability is achieved.

Description

technical field [0001] The present invention mainly relates to a preparation method of a chewable tablet, in particular, the present invention relates to the technical field of preparation of a black wolfberry proanthocyanidin chewable tablet. Background technique [0002] Black fruit wolfberry (Lycium Ruthenium Murr.) belongs to Solanaceae (Solanceae) Lycium genus (Lycium L.). It is a unique salt-tolerant and drought-resistant wild plant in Northwest my country. It has the effects of strengthening the kidney, nourishing the liver, improving eyesight, invigorating the stomach, nourishing the brain, anti-aging and stimulating the menstrual flow. "Jingzhu Materia Medica" records that wolfberry black fruit is used to treat heart fever, heart disease, irregular menstruation, menopause, etc., and has significant medicinal effects. It is used as a nourishing and strong antihypertensive medicine in the folk. [0003] Black wolfberry is rich in natural proanthocyanidins, commonly kn...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/20A61P1/00A61P1/04A61P39/06A23L33/105A61K31/352
CPCA61K36/815A23V2002/00A61K9/0056A61K9/2018A61K31/352A61K2236/333A61K2236/55A61K2300/00A23V2200/32A23V2200/30A23V2250/21A23V2250/21166
Inventor 丁慧玲谢晓凤童莲花王亮蔡远强
Owner XINJIANG YUANSEN KANGLE BIOTECH
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