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Quickly released oral cavity nursing mouthwash refreshing tablet and preparation method and application thereof

A technology of oral care and fresh tablet, which is applied in the field of oral care, can solve the problems of unsatisfactory bactericidal effect, low bioavailability, long action time, etc., and achieve the effects of convenient use, shortened action time, and convenient portability

Active Publication Date: 2017-01-11
北京瑞济善健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the bactericidal effect of existing products is usually unsatisfactory, the action time is long, and the bioavailability is not high

Method used

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  • Quickly released oral cavity nursing mouthwash refreshing tablet and preparation method and application thereof
  • Quickly released oral cavity nursing mouthwash refreshing tablet and preparation method and application thereof
  • Quickly released oral cavity nursing mouthwash refreshing tablet and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Take 0.01g of sodium fluoride and 3g of potassium nitrate and pass through a 100-mesh sieve for later use; 16g of citric acid, 37g of sodium bicarbonate, 3g of sodium benzoate, 10g of polyethylene glycol, 5g of povidone, 1.3g of essence, 23g of lactose, sodium saccharin 0.6g, menthol 0.5g, and silicon dioxide 0.3g are passed through an 80-mesh sieve for later use; the above powders are uniformly pressed into tablets. When pressing the tablet, the temperature is less than 18°C, and the air humidity is less than or equal to 40%.

Embodiment 2

[0047] Take 0.01g of sodium fluoride and 3g of potassium nitrate and pass through a 100-mesh sieve for later use; 17g of citric acid, 37g of sodium bicarbonate, 3g of sodium benzoate, 10g of polyethylene glycol, 5g of povidone, 3g of essence, 20g of lactose, and 0.6g of sodium saccharin g, 0.8 g of menthol, and 0.3 g of silicon dioxide are passed through an 80-mesh sieve for subsequent use; the above-mentioned powders are uniformly pressed into tablets. When pressing the tablet, the temperature is less than 18°C, and the air humidity is less than or equal to 40%.

Embodiment 3

[0049] Take 0.01g of sodium fluoride, 3g of potassium nitrate, 1g of sodium lauryl sulfoacetate through a 100-mesh sieve, and set aside; 3g of tartaric acid, 14g of citric acid, 37g of sodium bicarbonate, 3g of sodium benzoate, 10g of polyethylene glycol, and povidone 5g, essence 3g, lactose 19g, saccharin sodium 0.6g, menthol 0.8g, silicon dioxide 0.3g pass through 80-mesh sieve for later use; the above powder is uniformly pressed into tablets. When pressing the tablet, the temperature is less than 18°C, and the air humidity is less than or equal to 40%.

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Abstract

The invention discloses a quickly released oral cavity nursing mouthwash refreshing tablet, which comprises 0.01 to 10 weight percent of an active component, wherein the active component is one or more of a fluoride ion source, a potassium ion source and sodium lauryl sulpho acetate. Furthermore, the invention further discloses a preparation method and application of the quickly released oral cavity nursing mouthwash refreshing tablet. The quickly released oral cavity nursing mouthwash refreshing tablet can better clear away oral odor; furthermore, the tablet can efficiently assist fluoride ions and / or potassium ions to permeate into the surfaces of teeth, so that the bioavailability of resistance of dentine hypersensitivity is improved, and the action time is greatly shortened; moreover, the sodium lauryl sulpho acetate achieves a synergistic effect with the fluoride ion source and the potassium ion source to prevent fungal infection to an oral cavity and further increase the harmful bacteria clearance ratio and the proportion that the oral odor is completely covered; meanwhile, the refreshing tablet has the multiple effects on prevention and treatment of the oral cavity problems, such as functions of preventing and treating decayed teeth, diminishing inflammation, sterilizing, expelling sensation, stopping bleeding and refreshing the oral odor.

Description

technical field [0001] The invention belongs to the technical field of oral care, and relates to an oral care product, more specifically, to an immediate-release oral care mouthwash refreshing tablet and its preparation method and application. [0002] technical background [0003] The mouth is the beginning of the digestive tract and has many important functions. Oral care is an important part of basic care. First of all, healthy teeth can make people look good and feel better in daily life such as eating and talking. Secondly, good oral care for critically ill patients can avoid some complications, and the condition can be observed according to the health of the oral cavity. Third, disease in the oral cavity is a harbinger of disease in other parts of the body. For example, dry oral mucosa is the first signal of water and salt metabolism disorders; patients with anemia may have persistent oral ulcers and pharyngitis; patients with leukemia may have bleeding gums. Fourth...

Claims

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Application Information

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IPC IPC(8): A61K8/21A61K8/19A61K8/44A61Q11/00A61P1/02A61P37/08A61P31/10
CPCA61K8/19A61K8/21A61K8/447A61Q11/00
Inventor 张青贺付俊昌
Owner 北京瑞济善健康科技有限公司
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