Molecular traditional Chinese medicine sustained-release tablet for anti-bone loss and preparation method thereof
A slow-release tablet, anti-osteoporosis technology, applied in the field of traditional Chinese medicine, can solve the problems of large side effects, prone to complications, etc., and achieve the effects of increasing bone mass, high bioavailability, and maintaining blood concentration
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Embodiment 1
[0020] A molecular traditional Chinese medicine sustained-release tablet for anti-bone loss and a preparation method thereof. The molecular traditional Chinese medicine sustained-release tablet includes molecular traditional Chinese medicine components and pharmaceutically acceptable adjuvant components. 5 parts of chastity seed), 5 parts of weedule lactone (Eclipta japonica), 2 parts of paeoniflorin (Paeonia officinalis), 3 parts of psoralen (psoralen), 5 parts of diosgenin (yam); the ingredients of the excipients It is 30 parts of sodium alginate, 1 part of carbomer (934), 25 parts of hydroxypropyl methylcellulose, 20 parts of lactose, and 4 parts of magnesium stearate.
[0021] Described preparation method comprises the following steps:
[0022] (1) Weigh each molecule of traditional Chinese medicine ingredients in proportion and mix them evenly;
[0023] (2) Sodium alginate and hydroxypropyl methylcellulose are used as the skeleton material, and carbomer (934) is added as...
Embodiment 2
[0026] A molecular traditional Chinese medicine sustained-release tablet for anti-bone loss and a preparation method thereof. The molecular traditional Chinese medicine sustained-release tablet includes molecular traditional Chinese medicine components and pharmaceutically acceptable adjuvant components. Sedum chinensis) 2.5 parts, wedelolide (Eclipta chinensis) 2.5 parts, paeoniflorin (Paeonia officinalis) 1 part, psoralen (psoralen) 2 parts, diosgenin (yam) 2 parts. The excipients are 40 parts of sodium alginate, 3 parts of carbomer (934), 15 parts of hydroxypropyl methylcellulose, 30 parts of lactose and 2 parts of magnesium stearate.
[0027] Described preparation method comprises the following steps:
[0028] (1) Weigh each molecule of traditional Chinese medicine ingredients in proportion and mix them evenly;
[0029] (2) Sodium alginate and hydroxypropyl methylcellulose are used as the skeleton material, and carbomer (934) is added as the binder, then mixed with the mo...
Embodiment 3
[0032] A molecular traditional Chinese medicine sustained-release tablet for anti-bone loss and a preparation method thereof. The molecular traditional Chinese medicine sustained-release tablet includes molecular traditional Chinese medicine components and pharmaceutically acceptable adjuvant components. 1.5 parts of chastity seed), 1.5 parts of weedule lactone (Eclipta chinensis), 0.5 parts of paeoniflorin (Paeonia officinalis), 0.5 parts of psoralen (psoralen), 1 part of diosgenin (yam). The excipients are 45 parts of sodium alginate, 2 parts of carbomer (934), 20 parts of hydroxypropyl methylcellulose, 25 parts of lactose and 3 parts of magnesium stearate.
[0033] Described preparation method comprises the following steps:
[0034] (1) Weigh each molecule of traditional Chinese medicine ingredients in proportion and mix them evenly;
[0035] (2) Sodium alginate and hydroxypropyl methylcellulose are used as the skeleton material, and carbomer (934) is added as the binder, ...
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