Cyclocarya paliurus guava leaf hypoglycemic tea and its preparation method and application

A technology of willow guava and guava leaves, which is applied in the field of papaya paliurus guava leaf hypoglycemic tea and its preparation, which can solve unfavorable product quality and curative effect stability, does not involve scientific interpretation of drug effects, and cannot be used and absorbed by the human body and other problems, to achieve significant hypoglycemic effects, easy quality control, and easy utilization

Inactive Publication Date: 2019-12-20
GUANGDONG PHARMA UNIV +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned disclosed health-care teas all have a good curative effect on treating diabetes, but all have the following disadvantages: one is that the above-mentioned disclosed health-care teas all adopt the mode of boiling water to be brewed for drinking as tea, and cannot be more comprehensive and better utilize the medicinal materials. Functional components cannot be well utilized and absorbed by the human body; second, the composition of the above-mentioned health-care teas is complex, quality control is difficult, and the preparation procedure is lengthy, which is not conducive to the stability of product quality and curative effect; effective in-depth scientific interpretation

Method used

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  • Cyclocarya paliurus guava leaf hypoglycemic tea and its preparation method and application
  • Cyclocarya paliurus guava leaf hypoglycemic tea and its preparation method and application
  • Cyclocarya paliurus guava leaf hypoglycemic tea and its preparation method and application

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Experimental program
Comparison scheme
Effect test

Embodiment 4

[0035] Embodiment 4, preparation method of hypoglycemic tea of ​​the present invention

[0036] A) Cyclocarya paliurus pretreatment:

[0037] S1. Harvesting and selection of original leaves: select leaf buds or young leaves with light green color, thick texture, no disease spots, and no pests, wash them, remove dust and microorganisms on the leaf surface, drain the water, and spread them evenly in a ventilated and dry place;

[0038] S2. Withering: naturally wither for 3 hours, and turn it up and down once in the middle until the leaves are soft and the water loss rate is 8%.

[0039] S3. Finishing: frying the withered leaves of Cyclocarya paliurus to stop the enzymatic reaction;

[0040] S4. Stir-frying: Put the finished leaves into a frying pan with an inclination of 35°, control the temperature at 80°C and stir-fry continuously for 4 minutes, until the leaves are soft, hold them into a ball, hold them loosely, and smell clearly The smell disappears, slightly fragrant; ...

Embodiment 5

[0049] Example 5 Inhibition Test of α-Glucosidase

[0050] 1. Experimental method:

[0051] 1.1 Extraction and concentration

[0052] With the hypoglycemic tea described in Comparative Example 1 as the positive control group, take Cyclocarya paliurus and guava leaves and mix them in ratios of 10:0, 7:3, 5:5, 3:7 and 0:10, and take the tea in Comparative Example 1 Add 10 g of sugar tea and samples of various ratios to 500 ml of distilled water, bathe in 90°C water for 30 minutes, filter with suction, and concentrate the filtrate to 10 ml by rotary evaporation, and store it for later use.

[0053] 1.2 Dilution

[0054] Dilute the concentration in each ratio with PBS buffer solution to the concentration in the table below to obtain each test sample.

[0055]

[0056]

[0057] 1.3 Determination of enzyme activity

[0058] Add 100 μl of enzyme solution to each test product, keep the temperature at 37°C for 15 minutes, add 50 μl of the preheated substrate (PNPG / PNPB), keep...

Embodiment 6

[0071] Example 6 Effect of Cyclocarya paliurus on type Ⅰ diabetic mice

[0072] Study 1. Effect of Cyclocarya paliurus on blood sugar in type Ⅰ diabetic mice

[0073] 1 Experimental method:

[0074] 1.1 Modeling

[0075] 15 male mice were taken as the normal control group without modeling, and the other male mice that had been adaptively fed were fasted for 12 hours, and STZ 130 mg / kg was injected intraperitoneally, and the normal control group was injected with citrate buffer intraperitoneally. Feed normally after injection of STZ, and supplement 10% glucose water appropriately. Two weeks later, the mice were fasted for 12 hours, their tails were cut to collect blood, and their fasting blood glucose was measured with a blood glucose meter. The mice with fasting blood glucose ≥ 11.1 mmol / L were selected as type Ⅰ diabetic mice.

[0076] 1.2 Administration of animals in groups

[0077] The modeled mice were divided into 3 groups: model group, positive drug group (metfor...

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Abstract

The invention belongs to the field of healthcare food and particularly relates to a cyclocarya paliurus-guava leaf blood glucose reducing tea as well as a preparation method and application thereof. The cyclocarya paliurus-guava leaf blood glucose reducing tea consists of superfine powder of cyclocarya paliurus and superfine powder of guava leaf in a weight ratio of 1:(0.4-9). The blood glucose reducing tea provided by the invention has simple ingredients and realizes a remarkable effect of reducing blood glucose; the preparation technology is simple while the cost is low; and the blood glucose reducing tea is nontoxic and harmless to human body, avoids drug resistance and can be taken for long.

Description

technical field [0001] The invention belongs to the field of health food, and in particular relates to a papaya paliurus guava leaf hypoglycemic tea and a preparation method and application thereof. Background technique [0002] Diabetes has become the third major disease among non-communicable chronic diseases in my country (cardiovascular disease, tumor, diabetes). development of. The speed of its incidence increases, it involves a wide range of people, consumes a lot of health resources, and causes disability and death to an astonishing degree. Therefore, the prevention and control of diabetes is a major health problem to be solved urgently in our country. [0003] Diabetes is called diabetes in traditional Chinese medicine. It is characterized by polydipsia, polyuria, polyphagia, weight loss, fatigue, and sweet urine. The diseased sites are lung, stomach, and kidney. Most modern scholars believe that the basic pathogenesis of diabetes is the depletion of yin fluid and ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23F3/34
CPCA23F3/34
Inventor 曾宇杨再刚陈小雪李书渊杨仟曾常青赵宇红黄宝媛莫兴春陈旺张礼行李潇丁瑞瑞刑增智
Owner GUANGDONG PHARMA UNIV
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