Application of spirulina powder as binder

A technology of spirulina algae powder and binder, which is applied in the direction of alginic acid binder, adhesive, non-polymer binder additives, etc., to achieve the effects of resisting cancer cell proliferation, improving immune function, and reducing production energy consumption

Inactive Publication Date: 2018-07-20
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Most of the auxiliary materials in the traditional tableting process are some non-natural chemical products such as microcrystalline cellulose, micropowder silica gel, sodium carboxymethyl starch, stearyl fumaric acid vinyl acetate, magnesium stearate, vinyl pyrrolidone, etc. Although these products are Inert substance, but long-term use will inevitably cause negative effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1, high-sugar spirulina algae cultivation

[0020] Spirulina cells are cultured in a nutrient-rich medium (Zarrouk) prepared with deionized water containing: NaHCO per liter of water 3 16.8g, K 2 HPO 4 0.5g, NaNO 3 2.5g, K 2 SO 4 1g, NaCl 1g, MgSO 4 ·7H 2 O 0.2g, CaCl 2 2H 2 O 0.04g, FeSO 4 ·7H 2 O 0.01g, H 3 BO 3 2.86mg, MnCl 2 4H 2 O 1.86mg, ZnSO 4 ·7H 2 O0.22mg, Na 2 MoO 4 2H 2 O 0.39mg, CuSO 4 ·5H 2 O 0.08mg. Initial inoculation density OD 560 0.5, culture temperature 30±2℃, continuous single-row light, light intensity 200μmol m –2 the s –1 , into the air flow rate of 0.4vvm. The polysaccharide accumulation process was carried out in a 6L plastic square basin with a water depth of 8cm.

[0021] Grow to OD 560 3 cells were centrifuged at 4000rpm for 5min, the supernatant was discarded, and the algal mud was used without NaNO 3 Zarrouk medium (Zarrouk-N) was washed once and then resuspended in Zarrouk-N to adjust the cell den...

Embodiment 2

[0026] Embodiment 2, large-scale high-sugar spirulina production

[0027] Large-scale cultivation of Spirulina using N limitation in an outdoor racetrack pond for enhanced biomass and polysaccharide yields.

[0028] The process of algae cultivation and polysaccharide accumulation was carried out in an outdoor 1-acre track pool with a water depth of 30 cm and a water flow velocity of 20 cm / s.

[0029] 1) Cultivation of algal species

[0030] Spirulina cells are cultured in nutrient-rich natural mother liquor alkali medium (MYJ), and the culture medium is prepared with underground fresh water, and each liter of water contains: 6g of mother liquor alkali (containing NaHCO 3 about 3.4g), NaNO 3 1g, KCl0.5g, H 3 PO 4 0.12g, FeSO 4 ·7H 2 O 0.01g, MgSO 4 ·7H 2 O 0.01 g. Initial inoculation density OD 560 0.3, the culture temperature is 32±5°C, the natural conditions are illuminated, and the maximum light intensity on the surface of the algae liquid is 3000 μmol m –2 the s ...

Embodiment 3

[0037] Embodiment 3, high-sugar spirulina algae powder tabletting

[0038] According to the traditional spirulina tabletting parameters, high-sugar spirulina powder is directly used to obtain stable algae tablets. Compared with the tablet obtained by conventionally adding 1-2% carboxymethylcellulose sodium, there is no significant difference in its appearance, friability, and disintegration time limit.

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Abstract

The invention relates to an application of high-polysaccharide spirulina powder. The application is concretely characterized in that the high-polysaccharide spirulina powder is obtained through changing spirulina culturing conditions, and is used in tabletting as a natural auxiliary material. A proper amount of the high-polysaccharide spirulina powder can be added in the tabletting process to substitute traditional adhesives, and also can provide certain nutrients, such as unsaturated fatty acids, essential amino acids and vitamins. The high-polysaccharide spirulina powder substitutes inert adhesives in traditional tabletting processes to achieve the advantages of safety, environmental protection, multiple nutrients and various colors, the exploitation of downstream products is facilitated, the development of spirulina industrialization is promoted, and a new idea for medicine and healthcare medicine tabletting is provided.

Description

technical field [0001] The invention relates to tabletting with high-sugar spirulina algae powder as an auxiliary material, in particular to a method for tableting medicine by adding high-sugar spirulina algae powder instead of traditional chemical inert binders. High-sugar spirulina is cultivated by controlling the addition of nutrient salts and adopting appropriate inoculation density, light, temperature and pH value to accumulate biomass and polysaccharides at the same time. Subsequent processing of algae powder can be used as an auxiliary material to replace traditional tablet adhesives (or binders), and can also be used in food, medicine, energy and other related fields. Background technique [0002] Spirulina is a kind of multicellular filamentous cyanobacteria (Blue Green Algae), also known as cyanobacteria (Cyanobacteria), belongs to Cyanophyta (Cyanophyta), Cyanophyceae (Cyanophyceae), Oscillatoriales (Oscillatoriales), Oscillatoriaceae (Osciallatoriaceae) ), Arthr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C09J199/00C09J105/04C09J11/06C12N1/20C12R1/01
CPCC09J199/00C09J11/06C09J105/04C12N1/20
Inventor 薛松李松曹旭鹏姚长洪陆洪斌
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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