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A nano-silver lady antibacterial balance gel that can prevent vaginitis

A nano-silver and gel technology, which is applied to local antibacterial agents, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., to achieve the effect of wide selection, low residue, and good antibacterial effect

Active Publication Date: 2021-08-06
沈平凡
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, while considering making the bacteriostatic agent into a gel preparation, it is also necessary to consider whether the preparation has a wide range of selectivity to the object of action, whether it can widely inhibit the growth of harmful bacteria, and adjust the balance of microorganisms in the vagina. The selectivity and safety of the program provided by the advanced technology for vaginal bacteria still need further improvement

Method used

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  • A nano-silver lady antibacterial balance gel that can prevent vaginitis
  • A nano-silver lady antibacterial balance gel that can prevent vaginitis

Examples

Experimental program
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Effect test

preparation example Construction

[0052]In a preferred embodiment, the preparation method of the extract I includes the following steps:

[0053] (1) Get the required weight of Aloe, Rhizoma Chuanxiong and Baibu powder and add 12 times the weight of 40wt% ethanol to stir, heat and reflux for extraction for 3 hours, the temperature is reduced to 30 ° C, filter, and the filtrate is concentrated to obtain the crude extract I, and then Dissolve the crude extract I in 40wt% ethanol to prepare a 30mg / ml solution, which will be used as an adsorption resin adsorption stock solution for later use;

[0054] (2) Get the adsorption stock solution obtained in the step (1) and pass it through a chromatographic column to absorb, desorb and purify the crude extract I, concentrate and dry to obtain the extract I; wherein the eluent used is 50wt% ethanol and acetonitrile, the volume ratio is 2.5:1; the washing speed is 3.8ml / min.

[0055] In the preparation process of the extract I in the present invention, the remaining opera...

Embodiment 1

[0075] Embodiment 1 provides a kind of nano-silver composition, and described nano-silver composition comprises A component and B component, and described A component comprises the 1,2-propanediol of 5 parts by weight, the glycerol of 15 parts by weight, 0.1 The methylparaben of weight part, the carbomer of 1 weight part, the caprylic triglyceride of 5 weight parts, the capric triglyceride of 3 weight parts, the petrolatum ester of 5 weight parts, the polydimethyl Silicone, 1 weight part of polyglycerol-3 methyl glucose distearate, 5 weight parts of glycerol stearate, 0.1 weight part of phenoxyethanol, 0.1 weight part of propylparaben, 0.5 weight part The cyclopentasiloxane of part, the ethylhexylglycerin of 5 parts by weight;

[0076] The B component includes 2 parts by weight of egg yolk, 1.5 parts by weight of oxidized corn oil, 5 parts by weight of borneol, 30 parts by weight of plant extracts, and 0.01 parts by weight of nano silver.

[0077] The weight ratio of the A co...

Embodiment 2

[0082] Embodiment 2 provides a kind of nano-silver composition, and described nano-silver composition comprises A component and B component, and described A component comprises the 1,2-propanediol of 10 weight parts, the glycerin of 20 weight parts, 0.2 The methylparaben of parts by weight, the carbomer of 3 parts by weight, the caprylic triglyceride of 8 parts by weight, the capric triglyceride of 7 parts by weight, the petrolatum ester of 10 parts by weight, the polydimethyl Silicone, 3 parts by weight of polyglycerol-3 methyl glucose distearate, 10 parts by weight of glyceryl stearate, 0.1 parts by weight of phenoxyethanol, 0.2 parts by weight of propylparaben, 1.5 parts by weight Parts of cyclopentasiloxane, 10 parts by weight of ethylhexylglycerin;

[0083] The B component includes 7 parts by weight of egg yolk, 3 parts by weight of oxidized corn oil, 7 parts by weight of borneol, 35 parts by weight of plant extracts, and 0.03 parts by weight of nano silver.

[0084] The...

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Abstract

The invention relates to the field of women's health products, in particular to a women's antibacterial and balancing gel that can prevent vaginitis. The bacteriostatic balance gel includes a nano-silver composition, the nano-silver composition includes A component and B component, and the A component includes 1,2-propylene glycol, glycerin, methylparaben, carbomer , Caprylic Triglyceride, Capric Triglyceride, Petrolatum, Dimethicone, Polyglyceryl-3 Methyl Glucose Distearate, Glyceryl Stearate, Phenoxyethanol, Propylparaben , cyclopentasiloxane, ethylhexylglycerin; the B component includes egg yolk, oxidized corn oil, borneol, plant extracts, and nano silver.

Description

technical field [0001] The invention relates to the field of women's health products, in particular to a women's antibacterial and balancing gel that can prevent vaginitis. Background technique [0002] Vaginitis is a common disease in women. According to WHO's global epidemiological survey in 2002, the global incidence rate of women's reproductive tract infection exceeded 60%. In 2002, an epidemiological survey of vaginitis among unmarried women under the age of 22 in 14 cities across the country organized by the First Affiliated Hospital of Peking University showed that the incidence rate exceeded 55%. Vaginitis is mainly divided into bacterial, trichomonal and candida, mixed infection is more common clinically. The pathogenesis of vaginitis is mainly related to the imbalance of local flora in the vagina. The normal vagina is parasitic with Lactobacillus, Streptococcus, Staphylococcus epidermidis and many other flora. These bacteria maintain a certain proportion and main...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/904A61K33/38A61K9/06A61K47/44A61K47/06A61K47/32A61K47/14A61P15/02A61P31/02A61P17/04A61P31/18A61K31/045
CPCA61K9/0034A61K9/06A61K31/045A61K33/38A61K36/232A61K36/234A61K36/236A61K36/286A61K36/489A61K36/537A61K36/886A61K36/896A61K36/904A61K47/06A61K47/14A61K47/32A61K47/44A61K2236/333A61K2236/55A61P15/02A61P17/04A61P31/02A61K2300/00
Inventor 沈平凡
Owner 沈平凡
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