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A polyacrylic acid/graphene oxide nanocomposite material combined with supramolecular interaction and its preparation method and application

A technology of nanocomposites, polyacrylic acid, applied in the direction of nanotechnology, nanotechnology, nanotechnology, etc. for materials and surface science

Active Publication Date: 2022-03-15
TIANJIN AGRICULTURE COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In previous studies, acrylic acid polymers were mostly modified on graphene oxide by chemical methods such as click chemistry or in situ polymerization, and graphene oxide and polyacrylic acid were linked by adamantane / cyclodextrin supramolecular interaction. has not yet been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Dissolve 3.02g of amantadine and 2.8mL of triethylamine in 25mL of dichloromethane, and dissolve them in a water bath at a temperature of 0°C; then dissolve 2.0mL of bromoisobutyryl bromide solution in 5.0ml of dichloromethane In the methane solution; the second mixed solution is slowly added dropwise to the first mixed solution through a constant pressure dropping funnel, and the approximate dropping time is controlled within 1.5h. After the sample was added dropwise, the reactant was stirred and reacted with a magnet for 1 h in a water bath at 0° C. in an ice-water bath, and then reacted at room temperature for 12 h. Observe the color change. After the reaction is completed, the obtained product is taken out, filtered, and concentrated by rotary evaporation. Pass through a silica gel column, combine the filtrates containing the product, spin evaporate again, and spin dry until white crystals appear, then store in a vacuum drying oven.

Embodiment 2

[0014] Add treated CuBr to the reaction tube respectively, N=1.0×10 -3 moles, PMDETA, N=1.0×10 - 3 moles and 2.0 mL of a mixed solvent of methyl ethyl ketone solution and isopropanol solution with a solution volume ratio of 7:3, and ultrasonically oscillated the mixed solution to form a homogeneous system. Add 2.1g AD-Br and 6.0mL mixed solvent with a solution volume ratio of 7:3 butanone / isopropanol to the reaction test tube, ultrasonically vibrate AD-Br to make it completely dissolved, and then start to react Add 9.0g of tert-butyl acrylate to the test tube, oscillate fully to mix the mixed solution evenly, then carry out liquid nitrogen freezing on the outside, vacuumize the inside of the bottle, vent nitrogen, and finally melt in a warm water bath. Under nitrogen freezing and vacuum conditions, the reaction tube must be in a closed state, and then transfer the reaction bottle to a 90°C oil bath to allow it to continue to react for 12 hours. After the reaction is complete...

Embodiment 3

[0016] Weigh 17.24g of β-cyclodextrin into a beaker, dissolve it in 200ml of 0.25mol / L NaOH solution, transfer it to a three-neck flask, add 11ml of 2.9g of p-toluenesulfonyl chloride dropwise with a constant pressure dropping funnel acetonitrile solution. React at room temperature for 3 hours, filter with suction, adjust pH to 2, keep at 4°C overnight. The separated precipitate was filtered and recrystallized with hot water as a solvent to obtain a white solid which was the product obtained. Take 1.5g of the above compound, add 23ml of ethylenediamine, stir to dissolve, then raise the temperature to 80°C, react for 4h, and evaporate the solvent under reduced pressure. The obtained solid was dissolved in 15 mL of hot water, and 150 mL of acetone was slowly added while stirring, the white precipitate was collected by filtration, and vacuum-dried at 40° C. for 7 h to obtain EDA-CD.

[0017] Put the required 150mg of graphene oxide into a 500ml round bottom flask, and then add ...

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PUM

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Abstract

The invention discloses a polyacrylic acid / graphene oxide nanocomposite material combined with the supramolecular action of adamantane / cyclodextrin, its preparation method and application. The composite material can load the drug with the conjugated system, which can prevent the loaded drug from being affected by the acidic environment and enzymes in the stomach. At the same time, the nanocomposite material can be used as a self-separation adsorbent for sewage treatment, because the polyacrylic acid polymer connected to graphene oxide through supramolecular action has pH responsiveness, so the composite material can adsorb dyes and pigments in sewage etc. By changing the pH value, the composite material can load pollutants and separate them from sewage.

Description

technical field [0001] The invention relates to a polyacrylic acid / graphene oxide nanocomposite material combined with adamantane / cyclodextrin supramolecular action and its preparation method and application. Background technique [0002] Graphene oxide was first prepared by Brodie in the mid-19th century. Compared with graphene, graphene oxide is still composed of sp 2 Hybridized carbon atoms form a large π bond structure and have a huge specific surface area, which allows it to adsorb chemical substances with similar structures, including drug molecules, etc., and graphene oxide can achieve a great deal in terms of adsorbing molecules such as drugs. High adsorption rate. On the other hand, unlike graphene, graphene oxide has a large number of oxygen-containing groups, which not only endows graphene oxide with good water solubility, but also endows it with good modifiability, and can be modified in various ways, so that it can It has better performance in terms of enviro...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L33/02C08K9/04C08K3/04C08F8/12C08F120/18C08B37/16B82Y30/00
CPCB82Y30/00C08B37/0012C08F8/12C08K3/042C08K9/08C08F120/18C08L33/02
Inventor 许艳玲尚志强韩智超马东生许文豪李晴张良顺
Owner TIANJIN AGRICULTURE COLLEGE