A kind of anticoagulant hemodialysis membrane and preparation method thereof

Abstract

The invention discloses a preparation method of an anticoagulant hemodialysis membrane. The preparation method comprises the following steps of (1) preparation of polysulfone amide polycondensate; (2)ester exchange of dimethyl(3-chloro-2-oxypropyl)phosphonate ester; (3) ionizing of the polysulfone amide polycondensate; (4) ion exchange; (5) forming of the membrane. The invention also discloses the anticoagulant hemodialysis membrane prepared by the preparation method. The anticoagulant hemodialysis membrane has the advantages that the anticoagulant property is realized, the biocompatibility is good, the water permeability and ultrafiltration rate are high, the clearing rate of toxin is high, and the mechanical property is excellent.

Description

technical field

[0001] The invention relates to the technical field of biomedical materials, in particular to an anticoagulant hemodialysis membrane and a preparation method thereof. Background technique

[0002] Hemodialysis is an effective alternative therapy for the treatment of acute and chronic renal failure. Clinically applied hemodialysis equipment consists of a dialysis machine, a water treatment system, a dialysate system and a dialyzer. Among them, the performance of the dialyzer directly affects the dialysis effect, and the hemodialysis membrane is the main part that determines the performance of the dialyzer. It uses the principle of a semi-permeable membrane and uses the solute gradient, osmotic gradient and water pressure gradient on both sides of the membrane to achieve It is a membrane material for the purpose of removing toxins and excessive water retention in the body, replenishing the substances needed in the body, and maintaining electrolyte and acid-base...

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