Yarn for cell culture support, and fabric for cell culture support including same

Abstract

Provided is a yarn for a cell culture support. The yarn according to an embodiment of the present invention includes a plurality of twisted monofilament strands, wherein at least a portion of the plurality of twisted monofilament strands are untwisted such that spaces are formed between the monofilament strands in order to prevent density-dependent inhibition of cultured cells and increase a specific surface area for cell contact. Accordingly, as a microenvironment yarn appropriate for the movement, proliferation, and differentiation of cells being cultured is realized, the cell proliferationrate and cell survival rate can be enhanced. Also, as a space for cell proliferation is maximally realized in a limited space in the support, a large amount of cells can be simultaneously cultured, and, because phenomenon of the suppression of cell proliferation due to contact between cells is prevented, cell proliferation can steadily continue. Furthermore, cells cultured through the yarn can becultured in a shape / structure that is more appropriate for being applied to an in vitro experimental model or being implanted in the body of an animal, and can be widely applied in various products used in cell culturing fields or tissue engineering fields such as bioreactors, cell culture containers, or kits for implantation in a body.

Description

technical field [0001] The present invention relates to a yarn for a cell culture scaffold, and more specifically, to a yarn for a cell culture scaffold, a ply yarn containing the same, and a fabric containing the same, that is, a yarn suitable for attachment, migration, proliferation, and differentiation of cultured cells. Microenvironment, thereby improving the survival rate of cells, cells can proliferate three-dimensionally, prevent density-dependent inhibition of contact between cells that proliferate in a limited space due to cell proliferation, and increase the specific surface area that multiple cells can contact . Background technique [0002] Recently, with the expansion of the utilization of cultured cells for disease treatment, interest and research on cell culture are increasing. Cell culture is a technique of taking cells from an organism and culturing them in vitro, differentiating the cultured cells into various body tissues such as skin, organs, nerves, etc...

AI Technical Summary

Problems solved by technology

[0005] However, the scaffolds for cell culture developed so far have a structure similar to that in vivo, and cells cannot be cultured in three dimensions, and the survival rate of cells is not high. appropriate question

[0006] Also, in the process of cell proliferation, since a plurality of cells cultured two-dimensionally or three-dimensionally in a limited space occurs density-dependent inhibition of growth between adjacent cells, there is an inability to Issues with growing cells to target levels

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