A skull restoration body for inducing bone regeneration and a preparation method thereof

A technology for bone tissue regeneration and restoration, applied in prosthesis, skull, additive manufacturing, etc., can solve the problems of fragility, brain tissue stimulation, deformed growth of new bone, etc., and achieve good biocompatibility and biocompatibility Good performance and maintain the effect of mechanical strength

Pending Publication Date: 2019-01-18
BEIJING ALLGENS MEDICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Metal materials include tantalum, titanium alloy or stainless steel, etc. The repair is a permanent implant, and long-term foreign body stimulation may cause complications and easily lead to abnormal growth of new bone
Non-metallic materials include plexiglass, bone cement and their composite materials, etc. Bone cement stimulates brain tissue, and is easy to deform and loose

Method used

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  • A skull restoration body for inducing bone regeneration and a preparation method thereof
  • A skull restoration body for inducing bone regeneration and a preparation method thereof
  • A skull restoration body for inducing bone regeneration and a preparation method thereof

Examples

Experimental program
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Embodiment 1

[0040] like figure 1 As shown, Embodiment 1 of the present invention provides a skull prosthesis for inducing bone tissue regeneration, which includes a three-layer structure, including an inner induction layer 1 , a support layer 2 and an outer induction layer 3 from inside to outside. Wherein, the support layer 2 is made of polyaryletherketone material whose mechanical strength is equivalent to that of the skull, such as figure 2 As shown, the support layer 2 has a grid structure with a plurality of grid holes 21 . Each mesh hole 21 communicates with the inner surface and the outer surface of the supporting layer, and each mesh hole 21 is filled with bioactive material that can induce bone tissue growth. Both the inner induction layer 1 and the outer induction layer 3 are made of bioactive materials capable of inducing bone tissue growth, and are respectively arranged on the inner surface and the outer surface of the supporting layer 2 .

[0041]The skull prostheses used ...

Embodiment 2

[0051] like image 3 As shown, the second embodiment of the present invention provides a method for preparing a bone tissue regeneration-inducing skull prosthesis, which is used to prepare the bone tissue regeneration-inducing skull prosthesis described in the above embodiment, which includes the following steps:

[0052] S1. Obtain the skull data of the patient;

[0053] S2. Perform three-dimensional reconstruction using the obtained skull data, and extract the digital model of the skull prosthesis and the support layer 2 according to the skull defect; the digital model of the skull prosthesis here is the overall digital model of the skull prosthesis including the support layer 2;

[0054] S3. According to the digital model of the support layer 2, using selective laser sintering 3D printing technology, the support layer 2 of the cranial prosthesis is printed with polyaryletherketone powder as raw material;

[0055] S4, according to the digital model of the skull prosthesis, ...

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Abstract

The invention relates to the technical field of medical devices, in particular to a skull restoration body for inducing bone tissue regeneration and a preparation method thereof. The skull restorationbody has biological activity and comprises an inner inducing layer, a supporting layer and an outer inducing layer sequentially from the inside to the outside. The support layer is made of polyaryletherketone material which is equivalent to human bone strength, hardness and weight, and plays a supporting role. The inner inducing layer and the outer inducing layer are made of bioactive material, respectively arranged on the inner surface and the outer surface of the supporting layer, have good bioactivity and osteoinductivity, and can induce bone tissue regeneration. The support layer is provided with a plurality of mesh holes, and each mesh hole is filled with a bioactive material, which can promote the exchange of nutrients inside and outside the skull repair body, and is conducive to the growth of tissue. The preparation method of the skull prosthesis builds a digital model according to the skull data of the patient, so that the skull prosthesis and the skull defect part have high matching degree, and the operation difficulty is reduced.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a skull prosthesis for inducing bone tissue regeneration and a preparation method thereof. Background technique [0002] When a patient undergoes craniotomy due to traumatic brain injury or intracranial disease, etc., it usually causes a skull defect. The skull defect makes the brain tissue lose its protective barrier and is easy to be injured. When the defect is large, it is accompanied by dizziness, headache, depression, and irritability. , anxiety and other symptoms, and affect the appearance, causing greater psychological harm to patients. With the help of cranial repair surgery and cranial prosthetics, the skull defect area can be repaired, so as to achieve the purpose of protecting brain tissue, reducing complications, and restoring the patient's appearance. [0003] At present, the materials used to make cranial prostheses mainly include natural biological materia...

Claims

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Application Information

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IPC IPC(8): A61F2/00A61F2/28A61F2/30
CPCA61F2/0063A61F2/2875A61F2/30942A61F2002/30943A61F2002/3093A61F2002/3097A61F2002/30968A61F2002/30948A61F2002/30985A61F2002/0086A61F2002/2835A61F2210/00Y02P10/25
Inventor 朱金亮宋天喜胡艳丽崔菡仇志烨崔云何志敏胡刚朱艳泽崔福斋
Owner BEIJING ALLGENS MEDICAL SCI & TECH
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