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Microemlusion gel for acne treatment and preparation method of microemlusion gel

A microemulsion gel and acne technology, which is applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc. and other problems, to achieve the effect of eliminating skin itching problem, rich luster, and less irritating effect.

Inactive Publication Date: 2019-03-08
罗永恒
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the treatment of acne, many chemically synthesized drugs are used, which are more harmful to the skin and irritating. It is difficult to remove acne and easily cause drug resistance of acne bacilli.
Many of the existing products often only choose a single natural extract to treat acne. Although it can play a certain effect, the effect is slow and the effective time is short, and acne cannot be cured well.

Method used

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  • Microemlusion gel for acne treatment and preparation method of microemlusion gel
  • Microemlusion gel for acne treatment and preparation method of microemlusion gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Preparation of Rapeseed Flower-Moringa Polypeptide:

[0033] Take fresh Moringa leaves without mildew spots, wash them with clean water, and then dry them, then crush the dried Moringa leaves into 20-mesh Moringa powder; wash fresh rapeseed flowers and dry them, and dry the dried rapeseed leaves The flowers are ground and pulverized into 20 mesh rapeseed pollen;

[0034] According to the mass ratio of 1:1, take Moringa powder and rape pollen respectively and mix them. After mixing Moringa powder and rape pollen evenly, add pure water to make the material-liquid ratio 1:5.0, adjust the pH value of the material liquid to 9.0, and then mix the After the feed solution is heated to 58°C, add alkaline protease and stir well, carry out enzymatic hydrolysis for 30 minutes, heat to 100°C for enzymatic deactivation treatment, and then adjust the pH value of the first enzymatic hydrolysis solution to 7.0 according to the weight of the substrate solution Add neutral protease at 2%...

Embodiment 2

[0044] Preparation of Rapeseed Flower-Moringa Polypeptide:

[0045] Take fresh Moringa leaves without mildew spots, wash them with clean water, and then dry them, then crush the dried Moringa leaves into 20-mesh Moringa powder; wash fresh rapeseed flowers and dry them, and dry the dried rapeseed leaves The flowers are ground and pulverized into 10 mesh rapeseed pollen;

[0046] According to the mass ratio of 1:1, take Moringa powder and rapeseed pollen and mix them respectively. After mixing Moringa powder and rapeseed pollen evenly, add pure water to make the material-liquid ratio 1:7.0, adjust the pH value of the material liquid to 9.0, and then mix the After the material liquid is heated to 60°C, add alkaline protease and stir well, carry out enzymatic hydrolysis for 26 minutes, heat to 100°C for enzymatic inactivation treatment, and then adjust the pH value of the first enzymatic hydrolysis solution to 6.5, and then adjust the pH value of the first enzymatic hydrolysis sol...

Embodiment 3

[0056] Preparation of Rapeseed Flower-Moringa Polypeptide:

[0057] Take fresh Moringa leaves without mildew spots, wash them with clean water, and then dry them, then crush the dried Moringa leaves into 30-mesh Moringa powder; take fresh rapeseed flowers, wash them, and dry them in the sun. The flowers are ground and pulverized into 20 mesh rapeseed pollen;

[0058] According to the mass ratio of 1:1, take Moringa powder and rapeseed pollen and mix them respectively. After mixing Moringa powder and rapeseed pollen evenly, add pure water to make the material-liquid ratio 1:6.0, adjust the pH value of the material liquid to 9.0, and then mix the After the feed solution is heated to 55°C, add alkaline protease and stir well, carry out enzymatic hydrolysis for 28 minutes, heat to 100°C for enzyme inactivation treatment, and then adjust the pH value of the first enzymatic hydrolysis solution to 6.0 according to the weight of the substrate solution Add neutral protease at 2% of th...

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Abstract

The invention belongs to the technical field of microemulsion gel processing and particularly relates to microemlusion gel for acne treatment and a preparation method of the microemlusion gel. The microemlusion gel is prepared from, by weight, 10-12 parts of tea tree oil, 12-15 parts of rape flower-moringa oleifera polypeptide, 6-8 parts of vitamin E, 4-6 parts of mint essential oil, 12-15 parts of Chinese herbal medicine extract, 20-25 parts of a surfactant, 15-20 parts of a cosurfactant, 15-18 parts of an oil phase, 1-3 parts of a modified carbomer gel matrix, 2-3 parts of preservatives, 0.5-1.2 parts of a transdermal agent, 0.5-1.0 part of a sun-screening agent and an appropriate amount of deionized water. The microemlusion gel is uniform, smooth, high in glossiness, beneficial to skinabsorption and effective in acne treatment and has antibacterial, anti-inflammatory and swelling and pain alleviating functions and the like.

Description

technical field [0001] The invention belongs to the technical field of microemulsion gel processing, in particular to a microemulsion gel for treating acne and a preparation method thereof. Background technique [0002] Acne is a chronic inflammatory skin disease of the pilosebaceous unit. It mainly occurs in adolescents and has a great psychological and social impact on adolescents. However, it can often be relieved or cured naturally after puberty, and individual patients can be extended to over 30 years old. Although acne is a disease with a tendency of self-healing, acne itself and the scars caused by untimely acne treatment can seriously affect the quality of life of patients, and cause mental pressure and economic burden of patients, which need to be paid attention to. Acne is more common on the cheeks, forehead, cheeks and nasolabial folds, followed by the chest, back and shoulders. Acne lesions are generally asymptomatic, and may be accompanied by pain when the infl...

Claims

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Application Information

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IPC IPC(8): A61K38/01A61K9/06A61K9/107A61K47/10A61K47/08A61K47/32A61K47/36A61P17/10A61P17/02A61K31/355A61K36/898
CPCA61K36/61A61K9/0014A61K9/06A61K9/1075A61K31/355A61K36/185A61K36/232A61K36/258A61K36/78A61K36/81A61K36/86A61K36/8969A61K36/898A61K38/011A61K47/08A61K47/10A61K47/32A61K47/36A61K2236/15A61K2236/333A61K2236/51A61K2236/53A61P17/02A61P17/10A61K2300/00
Inventor 罗永恒
Owner 罗永恒
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