Functional fruit and vegetable ferment solid beverage and preparation method thereof
A solid beverage, fruit and vegetable enzyme technology, applied in the direction of food science, can solve problems such as human injury, achieve the effect of improving body function, relieving and treating constipation, regulating and restoring gastrointestinal function
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Embodiment 1
[0025] Embodiment 1 laxative function experiment
[0026] 1. Materials and methods
[0027] 1.1 Experimental animals: SPF grade healthy Kunming mice, male. Provided by Beijing Weitong Lihua Experimental Animal Technology Co., Ltd., experimental animal production license: SCXK (Beijing) 2007-0001. The breeding environment is barrier grade, the temperature of the experimental environment is 23° C. to 24° C., and the humidity is 54% to 58%.
[0028] 1.2 Experimental method
[0029] 1.2.1 Animal grouping
[0030] Adult male Kunming mice, weighing 18-22 g, were selected and divided into 6 groups, 10 mice in each group, which were low-dose group, middle-dose group, high-dose group, blank control group, model group and positive control group. The low-dose group, the middle-dose group, and the high-dose group tested substance were 0.4, 0.8, 1.2g / kg health food prepared in embodiment 4, and the positive control group tested substance was 0.8g / kg Besunyen intestinal clear tea, and t...
Embodiment 2
[0049] Tablets are made according to Example 4, and the efficacy comparison test is carried out with the finished products reported in patent CN-201810052544.0 and CN-201711247255.8. With the same test method, the tablets made in Example 4 are used as the administration group, and the patent CN-201711247255.8 -201810052544.0 and CN-201711247255.8 reported that the finished products prepared by the prescription were control group 1 and control group 2, and the blank group and model group were normal saline with the same volume. The efficacy comparison test was carried out, and the test results were as follows:
[0050] Table 3 Effects on mouse small intestine propulsion rate, defecation time, and defecation grain number
[0051]
[0052] "*" means p<0.05 compared with the control group, and "**" means p<0.01 compared with the control group.
[0053] As can be seen from Table 3, compared with the model group, the ink propulsion rate, the first defecation time, the number of def...
Embodiment 3
[0054] Embodiment 3 human body food trial test
[0055] 1.1 Experimental method: Select 100 cases of constipation patients, all cases have constipation; randomly divide them into treatment group and control group. The treatment group consisted of 50 cases, 25 males and 25 females; aged 20 to 40 years. The control group consisted of 50 cases, including 25 males and 25 females; aged 20 to 40 years. There was no significant difference between the two groups in terms of age, gender, and disease duration (p>0.05). Samples were prepared in Example 6, and the control group was Rhubarb Tongbian Tablets. The samples in Example 6 and the control group were taken according to the instructions for use, and the experimental data were recorded according to the curative effect standard.
[0056] 1.2 Efficacy standard basis;
[0057] Relief: normal defecation, regular defecation.
[0058] Improvement: The frequency of defecation has increased.
[0059] Invalid: defecation without any eff...
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