Micro effervescent tablet with seaweed and baking soda and preparation method and application of micro effervescent tablet

A technology of baking soda and microbubbles, which is applied in the direction of medical formulas, medical raw materials derived from algae, medical preparations containing active ingredients, etc., can solve the problems of bad flavor, alkalosis, high price, etc., and achieve rich mineral content, Less side effects, good flavor effect

Pending Publication Date: 2019-08-09
SINO NUTRACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, long-term use of soda water may cause alkalosis, ranging from anorexia, nausea, headache, convulsions, to coma, especially for the elderly and patients with kidney disease. Long-term use is more likely to cause alkalosis
[0003] At present, most of the soda effervescent tablets on the market have a bad flavor and are dissolved through acid-base reaction; natural soda water tastes good, but the price is high; gout patients need to reduce uric acid, but taking soda for a long time will cause alkalosis, mild Anorexia, nausea, headache, convulsions, and coma in severe cases, especially for the elderly and patients with kidney disease

Method used

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  • Micro effervescent tablet with seaweed and baking soda and preparation method and application of micro effervescent tablet
  • Micro effervescent tablet with seaweed and baking soda and preparation method and application of micro effervescent tablet
  • Micro effervescent tablet with seaweed and baking soda and preparation method and application of micro effervescent tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031]

[0032]

[0033] Wherein, the plant extract is a mixture of dandelion, Sophora japonica and Pachyphyllum leaf extracts, the weight ratio of each component is: Dandelion extract: Sophora japonica extract: Pachyphyllum pachyrhiza extract=1:1:1: 1. Provided by Shaanxi Senfu Natural Products Co., Ltd.

[0034] Production method: 1. Baking soda granulation: granulate baking soda with 85% ethanol solution;

[0035] The weight ratio of baking soda to solvent is 5.7:1;

[0036] 2. Weigh the granulated baking soda and other materials (except polyethylene glycol), pass through a 20-mesh sieve, and mix for 15 minutes;

[0037] 3. After polyethylene glycol passes through an 80-mesh sieve, mix it with 2 for 5 minutes;

[0038] 4. Press the mixed powder of 3 into tablets, 600mg per tablet;

Embodiment 2

[0040]

[0041]

[0042] Wherein, the plant extract is a mixture of dandelion, Sophora japonica and Paebrania leaf extracts, the weight ratio of each component is: dandelion extract: Sophora japonica extract: Pachyphyllum phallus leaf extract=1:1:1,

[0043] Production Method:

[0044] 1. Baking soda granulation: Baking soda is granulated with a 5% maltodextrin solution by weight;

[0045] The weight ratio of baking soda to solvent is 9:1;

[0046] 2. Weigh the granulated baking soda and other materials (except sodium stearyl fumarate), pass through a 20-mesh sieve and mix for 15 minutes;

[0047] 3. Sodium stearyl fumarate passed through a 40-mesh sieve, mixed with 2 for 5 minutes;

[0048] 4. Press the mixed powder of 3 into tablets, 600mg per tablet;

Embodiment 3

[0055] Clinical Observation:

[0056] (1) Clinical data

[0057] A clinical trial was conducted on 245 patients with gouty arthritis. These patients all had symptoms of joint pain and swelling in varying degrees, and the course of the disease was 1-3 years. There were 155 males and 90 females. The treatment group included 130 cases (Example 1: 70 persons; Embodiment 2: 60 persons), and the control group 115 cases (Comparative Example 1: 60 persons; Comparative Example 2: 55 persons).

[0058] (2) Treatment method

[0059] The control group was given comparative example 1 and comparative example 2; the treatment group took orally the embodiment 1 and embodiment 2 of the present invention, 2 times a day, 2 tablets each time; cycle 15 days

[0060] (3) Judgment criteria for curative effect:

[0061] Significantly effective: no pain in the knee joint, no tenderness around the joint, no swelling of the joint, and the range of motion of the joint is 130°.

[0062] Effective: Sl...

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PUM

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Abstract

The invention discloses a micro effervescent tablet with seaweed and baking soda and a preparation method and application of the micro effervescent tablet. The micro effervescent tablet comprises, bypercentage, 25-50% of baking soda, 1-10% of seaweed powder, 5-20% of fruit powder, 10-40% of lactose, 10-40% of mannitol, 1-15% of a plant extract, 0.02-5% of a buffer agent, 0.2-2% of stevioside and0.3-8% of a lubricant. The micro effervescent tablet similar to natural soda water is compounded with seaweed powder with rich mineral substances and specific fruit powder with rich mineral substances, and a mixture with the buffer agent and the plant extract (dandelion, flos sophorae and lophatherum gracile extracts) is added to the micro effervescent tablet, so that the micro effervescent tablethas high mineral substance content and is good in flavor, more economic and high in bioavailability, also has a small side effect and a function of reliving gastric acid and can further achieve the functions of relieving the joint pain, preventing the gout and reducing the uric acid.

Description

technical field [0001] The invention relates to a baking soda micro-effervescent tablet and a preparation method and application thereof. Background technique [0002] Soda water is weakly alkaline water, which can be quickly dissolved from soda effervescent tablets. Soda water is good for nourishing the stomach, because soda weak alkaline water can neutralize stomach acid. Soda water can help relieve symptoms of indigestion and constipation and has antioxidant and skin-aging effects. A new study published in the American Journal of Immunology claims that drinking soda every day can help alleviate autoimmune diseases such as rheumatoid arthritis. Dr. Paul O'Connor, a researcher at Augusta University in the United States, and his research team completed rat and human experiments and found that drinking soda water in rats or healthy people can not only prompt the stomach to produce more gastric acid for better digestion Foods eaten with meals also moderate the immune respon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/46A61K36/899A61K47/02A61P19/02A61P29/00A61P19/06A61P3/02A61P1/04A61K33/00
CPCA61K9/0007A61K9/2009A61K33/00A61K36/02A61K36/288A61K36/489A61K36/732A61K36/736A61K36/752A61K36/899A61P1/04A61P3/02A61P19/02A61P19/06A61P29/00A61K2300/00
Inventor 顾茂健苏健梅
Owner SINO NUTRACEUTICAL CO LTD
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