Doxycycline hydrochloride-containing medicine for treating animal hysteritis and preparation method thereof
A technology of doxycycline hydrochloride and doxycycline, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, drug combinations, etc., can solve problems such as easy sticking, short duration of action, and poor therapeutic effect. To achieve long-lasting effect and good effect
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[0046] Such as figure 1 Shown, the preparation method of the medicine that contains doxycycline hydrochloride treatment animal metritis provided by the invention comprises:
[0047] S101, drying the granulated acid-base granules in an oven at 60--65°C for 3-5 hours. Control the water content of the granules to 3-4%, and make 12 mesh whole granules.
[0048] S102, the acid-base granules are added together with the excipients magnesium stearate, borneol, and sodium starch glycolate and mixed with a two-dimensional mixer for 30 minutes, and the semi-finished product is determined to be qualified and then compressed into tablets.
Embodiment 1
[0051] The medicine containing doxycycline hydrochloride for treating animal metritis provided by the embodiments of the present invention consists of 2.4kg of doxycycline hydrochloride, 0.6kg of lactic acid TMP, 1.5kg of Houttuynia cordata extract, 0.6kg of Angelica sinensis extract, Patrinia extract 1.5kg, Astragalus polysaccharide 1.5kg, Scutellaria baicalensis extract 1.2kg, tartaric acid 10kg, sodium lauryl sulfate 1.2kg, lactose 8kg, corn starch 12kg, absolute ethanol 4kg, sodium bicarbonate mixture 22kg, hard Composition of magnesium fatty acid mixture 0.8kg and sodium starch glycolate 2.4kg.
Embodiment 2
[0053] The medicine containing doxycycline hydrochloride for the treatment of animal metritis provided by the embodiments of the present invention consists of 4 kg of doxycycline hydrochloride, 1.0 kg of lactic acid TMP, 2.5 kg of Houttuynia cordata extract, 1.0 kg of Angelica sinensis extract, Salmonella extract 2.5kg, astragalus polysaccharide 2.5kg, scutellaria baicalensis extract 2.0kg, tartaric acid 14kg, sodium lauryl sulfate 2.4kg, lactose 12kg, corn starch 20kg, absolute ethanol 4kg, sodium bicarbonate mixture 30kg, stearin Composition of 1.2kg of magnesium acid mixture and 2.4kg of sodium starch glycolate.
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