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Antibacterial, bacteriostatic and halitosis-resistant toothpaste prepared by mixing natural extracts and vitamin C, and preparation method thereof

A technology of natural extracts and manufacturing methods, applied in the field of antibacterial, antibacterial, anti-halitosis toothpaste and manufacturing, can solve the problems of low stability, narrow antibacterial spectrum, pigment, etc., and achieve the effect of outstanding antiseptic effect and simple process

Pending Publication Date: 2020-08-07
YIWU AISHANG COMMODITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the natural active substances used as natural preservatives cannot be commercialized due to pigmentation, low stability, narrow antibacterial spectrum, reformation problems, etc., only DF of magnolia extract and grapefruit extract A very small part such as -100 is commercialized

Method used

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  • Antibacterial, bacteriostatic and halitosis-resistant toothpaste prepared by mixing natural extracts and vitamin C, and preparation method thereof
  • Antibacterial, bacteriostatic and halitosis-resistant toothpaste prepared by mixing natural extracts and vitamin C, and preparation method thereof
  • Antibacterial, bacteriostatic and halitosis-resistant toothpaste prepared by mixing natural extracts and vitamin C, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0041] The preparation of natural extract possesses and comprises the following steps:

[0042] (1) Quantify licorice, grape seed extract, scutellaria baicalensis, ginkgo leaf extract and grapefruit respectively, then wash and dry with purified water;

[0043] (2) Add 300-600ml of ethanol with a concentration of 60-80% to licorice, grape seed extract, scutellaria baicalensis, ginkgo leaf extract and grapefruit raw materials, and extract at 3-5°C for 2-4 days Active ingredients;

[0044] (3) The active ingredients of licorice, grape seed extract, scutellaria baicalensis, ginkgo leaf extract and grapefruit are filtered through a pressure reducer and fertilizer paper, and concentrated to a high-concentration extract using a rotary concentrator;

[0045] (4) After filtering the concentrated high-concentration extract with fertilizer paper, quantify it with distilled water;

[0046] (5) The respective extracts consisting of quantitative licorice, grape seed extract, scutellaria b...

Embodiment 1

[0063] Antiseptic activity test of natural extract (NP-5): take out 1ml of natural extract of the present invention and 9ml of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, human Candida albicans, each bacterial strain culture fluid of Aspergillus niger mix . The concentration of the strain culture solution added at this time was about 1.0×10 5 , the content of the extract is 10% of the whole volume. The mixed extracts were stored at 25° C., and 1 ml was put into solid medium after 3 days / 1 week / 2 weeks / 3 weeks, respectively. At this time, Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa were cultured on trypticase soybean agar medium, human Candida albicans, and Aspergillus niger on PDA solid medium. Cultivate Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa at 37°C for 2 days, cultivate human Candida albicans, and Aspergillus niger at 27°C for 3 days, and perform cell counting after the cultivation is completed. The...

Embodiment 2

[0070] Antiseptic activity test of vitamin C mixture: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, human Candida albicans, Aspergillus niger and vitamin C mixture were mixed. The strain concentration was 1.0×10 5 , the total volume is 10ml, because the mixing ratio of the vitamin C mixture is 2%, 5%, 7%, 10%, and 20%, so the respective concentrations are also different. Then take Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, human Candida albicans, Aspergillus niger and vitamin C mixture 1ml and put it on the solid medium, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa Agar medium, human Candida albicans and Aspergillus niger were cultured on PDA solid medium. Cultivate Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa at 37°C for 2 days, and cultivate human Candida albicans and Aspergillus niger at 27°C for 3 days. After the culture is completed, count the cells and measure the concentration of vitamin...

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Abstract

The invention discloses an antibacterial, bacteriostatic and halitosis-resistant toothpaste prepared by mixing natural extract and vitamin C. The antibacterial, bacteriostatic and halitosis-resistanttoothpaste comprises the natural extract and a vitamin C mixture, wherein the natural extract comprise liquorice, grape seed extract, scutellaria baicalensis, ginkgo leaf extract and grapefruit according to a mass ratio of the liquorice to the grape seed extract to the scutellaria baicalensis to the ginkgo leaf extract to the grapefruit is 1:3:2:5:2; and the vitamin C mixture comprises anhydrous citric acid, vitamin C, ascorbic acid vitamin C, refined salt and lactic acid. The antibacterial, bacteriostatic and halitosis-resistant toothpaste prepared by mixing the natural extract and the vitamin C has a very outstanding preservative effect on escherichia coli, staphylococcus aureus, pseudomonas aeruginosa, candida albicans and aspergillus niger strains, has an antibacterial effect on porphyromonas gingivalis, streptococcus mutans and helicobacter pylori strains, can be used as an antibacterial agent in an oral cavity, can replace an existing chemical preservative, and is simple in process of producing a large amount of natural preservatives.

Description

technical field [0001] The invention relates to the technical field of natural preservatives, in particular to an antibacterial, antibacterial, anti-halitosis toothpaste prepared by mixing natural extracts and vitamin C and a manufacturing method thereof. Background technique [0002] In many products such as food, pharmaceuticals, daily necessities, and cosmetics that are widely used around our lives, preservatives that are allowed to be used by the human body are added to prevent changes in the internal physical properties of the product and to preserve the product for a period of time. Most cosmetics use chemical preservatives such as parabens to prevent product deterioration, but the side effects of these preservatives on skin irritation are becoming more and more serious, and consumers' resentment is becoming more and more serious. In a broad sense, preservatives refer to additives used in food, pharmaceuticals, and cosmetics to maintain nutrition and freshness, and to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9771A61K8/67A61Q11/00A61P1/02A61P31/02A61P31/04A61P31/10A61K36/87A61K31/375
CPCA61K8/9789A61K8/9771A61K8/676A61Q11/00A61P1/02A61P31/02A61P31/04A61P31/10A61K36/484A61K36/87A61K36/539A61K36/16A61K36/752A61K31/375A61K2800/524A61K2300/00Y02A50/30
Inventor 赵国盛
Owner YIWU AISHANG COMMODITY
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