Direct-compression type organic calcium vitamin D3 chewable tablet and preparation method thereof

A vitamin and organic calcium technology, applied in the direction of organic active ingredients, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem of unreasonable daily intake design, affecting the absorption and solubility of other substances Problems such as low absorption rate, to achieve the effect of preventing rickets in young children, high solubility and absorption rate, simple and mature process

Pending Publication Date: 2021-02-19
广州富诺营养科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the vitamin D calcium soft capsule has a stimulating effect on the stomach and will affect the absorption of other substances
[0009] At present, calcium supplement health products on the market have problems such as low solubility and absorption rate, unreasonable design of daily intake, and general products for the crowd.

Method used

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  • Direct-compression type organic calcium vitamin D3 chewable tablet and preparation method thereof
  • Direct-compression type organic calcium vitamin D3 chewable tablet and preparation method thereof
  • Direct-compression type organic calcium vitamin D3 chewable tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1, a kind of direct compression type organic calcium vitamin D3 chewable tablet

[0033] The direct-compression type organic calcium vitamin D3 chewable tablet is composed of the following ingredients and parts by weight: 50 parts of calcium citrate, 40 parts of L-calcium lactate, 25 parts of microcrystalline cellulose, 1 part of anhydrous glucose, D-mannose 10 parts of sugar alcohol, 1 part of polyethylene glycol 6000, 5 parts of vitamin D3, 0.5 part of polydextrose, 1 part of sucralose, 0.5 part of magnesium stearate.

[0034] Such as figure 1 Shown, the preparation method of described direct compression type organic calcium vitamin D3 chewable tablet, comprises the steps:

[0035] S1. Remove calcium citrate, L-calcium lactate, microcrystalline cellulose, anhydrous dextrose, D-mannitol, polyethylene glycol 6000, vitamin D3, polydextrose, sucralose, and magnesium stearate. Packaged and irradiated under UV light for 30 minutes;

[0036] S2, passing D-manni...

Embodiment 2

[0039] Embodiment 2, a kind of direct compression type organic calcium vitamin D3 chewable tablet

[0040] The direct-compression type organic calcium vitamin D3 chewable tablet consists of the following ingredients and parts by weight: 55 parts of calcium citrate, 45 parts of L-calcium lactate, 30 parts of microcrystalline cellulose, 3 parts of anhydrous glucose, D-mannose 15 parts of sugar alcohol, 3 parts of polyethylene glycol 6000, 10 parts of vitamin D3, 0.7 part of polydextrose, 3 parts of sucralose, 0.9 part of magnesium stearate.

[0041] Such as figure 1 Shown, the preparation method of described direct compression type organic calcium vitamin D3 chewable tablet, comprises the steps:

[0042] S1. Remove calcium citrate, L-calcium lactate, microcrystalline cellulose, anhydrous dextrose, D-mannitol, polyethylene glycol 6000, vitamin D3, polydextrose, sucralose, and magnesium stearate. Packaged and irradiated under UV light for 30 minutes;

[0043] S2, passing D-mann...

Embodiment 3

[0046] Embodiment 3, a kind of direct compression type organic calcium vitamin D3 chewable tablet

[0047] The direct-compression organic calcium vitamin D3 chewable tablet consists of the following ingredients and parts by weight: 60 parts of calcium citrate, 50 parts of L-calcium lactate, 35 parts of microcrystalline cellulose, 5 parts of anhydrous glucose, and D-mannose 20 parts of sugar alcohol, 5 parts of polyethylene glycol 6000, 15 parts of vitamin D3, 0.9 parts of polydextrose, 5 parts of sucralose, 1.3 parts of magnesium stearate.

[0048] Such as figure 1 Shown, the preparation method of described direct compression type organic calcium vitamin D3 chewable tablet, comprises the steps:

[0049] S1, remove: calcium citrate, L-calcium lactate, microcrystalline cellulose, anhydrous glucose, D-mannitol, polyethylene glycol 6000, vitamin D3, polydextrose, sucralose, magnesium stearate Outer packaging, irradiated under ultraviolet light for 30 minutes;

[0050] S2, passi...

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Abstract

The invention belongs to the technical field of production of health-care products, and particularly relates to a direct-compression type organic calcium vitamin D3 chewable tablet and a preparation method thereof. The vitamin tablet mainly consists of vitamin D3, calcium citrate, L-calcium lactate, D-mannitol, microcrystalline cellulose, anhydrous dextrose, polyethylene glycol 6000, sucralose, magnesium stearate and an absorption enhancer. Organic acid calcium is used in a calcium-added vitamin tablet disclosed by the invention, so that the calcium-added vitamin tablet is small in irritationto gastrointestinal tracts and higher in solubility and absorptivity; vitamin D3 is matched with polydextrose, the calcium citrate and the calcium lactate to be used, so that absorption and utilization of calcium are facilitated; and the vitamin D3 can prevent rickets of children and chondropathy of adults. The vitamin tablets are produced by adopting a direct compression method, and the preparation method is simple.

Description

technical field [0001] The invention belongs to the technical field of health product production, and in particular relates to a direct-pressed organic calcium vitamin D3 chewable tablet and a preparation method thereof. Background technique [0002] Calcium is the most abundant mineral element in the human body, accounting for about 1.5%-2.0% of the body weight, with a total weight of 1200-1300g, of which 99% exists in the bones and teeth, which constitute the body frame and serve as the body's calcium reserve ; The rest are distributed in blood, extracellular fluid and soft tissue cells, collectively referred to as miscible calcium pools, which maintain a dynamic balance with bone calcium. Basically, all life processes of the body require the participation of calcium, and the balance of calcium metabolism is an important factor for maintaining life and health. Calcium plays an extremely important physiological regulatory role in physiological processes such as nerve and m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K47/10A61K47/26A61K47/38A61K47/36A61K31/593A61K33/06A61K31/194A61K31/19A61P3/14
CPCA61K9/0095A61K9/0056A61K9/2031A61K9/2018A61K9/2054A61K9/205A61K31/593A61K33/06A61K31/194A61K31/19A61P3/14A61K2300/00
Inventor 程彦邓颖妍张晓洁
Owner 广州富诺营养科技有限公司
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