A wearable cloth-based electrochemical sweat sensing device and method

A sensing device and electrochemical technology, applied in the direction of blood characterization devices, electrochemical variables of materials, sensors, etc., can solve the problems of reducing the sensitivity of wearable sensors, the cumbersome manufacturing process of sensors, and the inability to discharge sweat in time, so as to improve sensitivity, The effect of low cost and easy replacement

Active Publication Date: 2022-05-03
SOUTH CHINA NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, wearable electrochemical sweat sensors are mostly based on polymer materials, such as polydimethylsiloxane (PDMS) and polyethylene terephthalate (PET). The production process is cumbersome
In addition, in the traditional three-electrode system, the working electrode and the reference electrode are on the same plane as the counter electrode, so the detected sweat cannot be discharged in time inside the sensor and accumulates on the surface of the working electrode, which greatly reduces the sensitivity of the wearable sensor.

Method used

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  • A wearable cloth-based electrochemical sweat sensing device and method
  • A wearable cloth-based electrochemical sweat sensing device and method
  • A wearable cloth-based electrochemical sweat sensing device and method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] In this embodiment, a wearable cloth-based electrochemical sweat sensing device, such as Figure 1-3 As shown, it includes a sweat collection layer, a sweat detection layer, a waste liquid collection layer and a fixed pressure sheet layer 5, and the sweat collection layer includes a sweat inlet 11, a sweat collection channel 12, a sweat collection area 8, a sweat drainage channel and a first electrode Contact, the sweat detection layer includes a cloth-based detection chip 7, the cloth-based detection chip includes a cloth-based carrier, an auxiliary unit and a sweat detection unit, the waste liquid collection layer includes a paper-based waste liquid collection sheet 6, the The paper-based waste liquid collection sheet is located above the cloth-based detection chip, and the fixed pressing layer includes a second electrode contact 2 and a magnet 3 for fixing the cloth-based detection chip and the paper-based waste liquid collection sheet. The second electrode contact C...

Embodiment 2

[0051] This embodiment provides a production and detection application process of a cloth-based detection chip as follows:

[0052] Chip preparation: use the Adobe Illustrator CS5 drawing software to design the configuration of the cloth-based three-dimensional three-electrode sweat detection chip, and use the front carbon screen printing technology to make the cloth chip electrode (that is, the three-dimensional three-electrode system, including the working electrode, reference electrode and counter electrode. ), constructing the hydrophobic wax dam of the cloth-based 3D sweat detection chip using the backside wax screen printing technique.

[0053] The unfolded structure of the obtained chip is as follows Figure 4 As shown (referred to as chip A in this embodiment), it includes a single-channel sweat detection chip working electrode 13, a single-channel sweat detection chip reference electrode 14, a hydrophilic region 15, a hydrophobic wax dam 16 and a single-channel sweat ...

Embodiment 3

[0058] This embodiment provides a process for glucose detection using a cloth-based detection chip:

[0059] Electrode modification: The electrode modification process is the same as in Example 2.

[0060] Detection: Prepare glucose standard solutions with concentrations of 0mM, 0.05mM, 0.1mM, 0.2mM, 0.3mM, 0.4mM, 0.5mM, 0.6mM, 0.7mM, 0.8mM, 0.9mM, and 1mM respectively, and set aside. Open the potentiostat program on the computer, select the chronoamperometry as the experimental method, set the scanning voltage to -0.1V, and scan time 100s. The working electrode of the potentiostat is connected to the working electrode of the three-dimensional cloth-based sweat detection chip. The reference electrode clip and the auxiliary electrode clip are respectively connected to the reference electrode and counter electrode of the three-dimensional cloth-based sweat detection chip, and the 0mM glucose standard solution is dripped on the three-dimensional cloth-based sweat detection chip, ...

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Abstract

The invention discloses a wearable cloth-based electrochemical sweat sensing device and method. The device includes a sweat collection layer, a sweat detection layer, a waste liquid collection layer and a fixed pressing layer. The sweat collection layer is used to quickly collect sweat on the skin surface. The sweat detection layer includes a folded cloth-based detection chip, the cloth-based detection chip includes a cloth-based carrier, an auxiliary unit and a sweat detection unit, the waste liquid collection layer includes a paper-based waste liquid collection sheet, and the fixed pressing layer is used to fix the cloth-based detection The chip and the paper-based waste liquid collection sheet are connected to the external circuit. Sweat penetrates into the hydrophilic area of ​​the cloth-based detection chip through the sweat collection layer, and then reaches the working electrode for detection. The paper-based waste liquid collection sheet absorbs the sweat overflowing from the working electrode, and the cloth-based detection chip transmits the detection signal to the external circuit for analysis. Finally, the sweat detection results are obtained, and the low-cost, non-invasive, stable real-time continuous monitoring of the sweat components on the human skin surface is realized, which is of great significance to the monitoring of human health status.

Description

technical field [0001] The invention relates to the technical field of electrochemical sensors, in particular to a wearable cloth-based electrochemical sweat sensing device and method. Background technique [0002] With the continuous development of electronic science and technology, and the deepening of research on wearable sensor devices, the research and development of smart medical products is also developing rapidly. The development of smart medical products is increasingly oriented towards the non-invasive detection of different biological fluids (such as saliva, sweat or tears) to enable continuous monitoring of (bio)markers relevant to clinical performance. Wearable sensors have broad application prospects in fields such as healthcare, fitness, security, and the environment due to their advantages of non-invasive and sustainable detection. [0003] Sweat is a common and readily available epidermal biofluid whose main component is water and contains metabolites (such...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/145A61B5/1477A61B5/1486G01N27/30G01N27/327
CPCA61B5/14517A61B5/1477A61B5/1486G01N27/327G01N27/308
Inventor 章春笋郑琳
Owner SOUTH CHINA NORMAL UNIVERSITY
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