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Ganoderma lucidum spore oil with protective effect on gastric mucosa, preparation method and equipment thereof

A technology of Ganoderma lucidum spore oil and protective effect, applied in the field of Ganoderma lucidum spore oil and its preparation, can solve the problems of increased operation time, unfavorable continuity, oxidation of crude products, etc., so as to prevent oxidation or pollution, protect gastric mucosa, and prevent damage Ulcer effect

Pending Publication Date: 2021-04-02
福建仙芝楼生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Conventional supercritical extraction equipment is only suitable for a single extraction. If the crude product in the separation tank I is to be extracted for the second time, it is necessary to open the extraction tank I and pour the crude product in the separation tank I, which is not conducive to The continuity of production not only increases the operation time, but also easily causes the crude product in the separation tank I to be oxidized by air or possibly polluted

Method used

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  • Ganoderma lucidum spore oil with protective effect on gastric mucosa, preparation method and equipment thereof
  • Ganoderma lucidum spore oil with protective effect on gastric mucosa, preparation method and equipment thereof
  • Ganoderma lucidum spore oil with protective effect on gastric mucosa, preparation method and equipment thereof

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preparation example Construction

[0038] The preparation process of Ganoderma lucidum spore oil is as follows: harvest mature Ganoderma lucidum spores, gather them into powder, sift out impurities, dry them until the water content is below 3%, break the wall, and then take a certain weight of broken Ganoderma lucidum spore powder and put it into supercritical extraction In the extraction kettle Ⅰ of the device, seal it, feed supercritical carbon dioxide, and perform the first supercritical extraction: the pressure of the extraction kettle Ⅰ is 20-30 MPa, the temperature of the extraction kettle Ⅰ is 40-50 °C, the pressure of the separation kettle Ⅰ is 8 MPa, and the temperature of the separation kettle Ⅰ Ⅰ 40~50℃, separation kettle III pressure 5~6MPa, separation kettle Ⅲ temperature 40~50℃, flow rate 550~650L / h, extraction time 5-7h, get Ganoderma lucidum spore crude oil from separation kettle Ⅰ, recycle and transport the Ganoderma lucidum spore crude oil Into the extraction kettle II, pass supercritical carbo...

Embodiment 1

[0044] Such as figure 2 As shown, the extraction, purification and separation equipment of the present invention is improved on the basis of conventional supercritical equipment, and additional extraction kettle II1-2, separation kettle II2-2, recovery pipeline 6, corresponding fine-tuning valve F, and collection valve are added. C and switch valve V, so that the whole set of equipment can simultaneously extract, purify and separate high-yield and high-purity precisely separated products.

[0045] That is, a supercritical double extraction, purification and separation equipment, which consists of extraction kettle Ⅰ1-1, extraction kettle Ⅱ1-2, recovery pipeline 6, separation kettle Ⅱ2-2, separation kettle Ⅰ2-1, separation kettle Ⅲ2-3, heat exchanger Ⅰ3-1, heat exchanger Ⅱ3-2, storage tank 4, high-pressure pump 5, connecting pipe 9, fine-tuning valve F, collection valve C, switch valve V and control system, the control system controls the working status of each component, the ...

Embodiment 2

[0057] Such as image 3 As shown, the extraction, purification and separation equipment of the present invention is improved on the basis of conventional supercritical equipment, and additional extraction kettle II, separation kettle II, recovery pipeline, corresponding fine-tuning valve F, collection valve C and switch valve V are added. , so that the whole set of equipment can be extracted, purified and separated with high yield and high purity at the same time.

[0058] That is, a supercritical double extraction, purification and separation equipment, which consists of extraction kettle Ⅰ, extraction kettle Ⅱ, recovery pipeline, separation kettle Ⅱ, separation kettle Ⅰ, separation kettle Ⅲ, heat exchanger Ⅰ, heat exchanger Ⅱ, storage tank, high pressure Pump, extraction pipeline Ⅰ, extraction pipeline Ⅱ, fine-tuning valve F, collection valve C and switch valve V and control system, the control system controls the working status of each component, extraction kettle Ⅰ and ext...

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Abstract

Provided is a ganoderma lucidum spore oil with a protective effect on gastric mucosa. The ganoderma lucidum spore oil is obtained by extracting ganoderma lucidum spore powder through a supercritical carbon dioxide double extraction technology, the oleic acid value of the ganoderma lucidum spore oil is smaller than or equal to 2 KOH (mg / g), and the peroxide value is smaller than or equal to 0.1%. Afirst extraction uses a supercritical carbon dioxide extraction technology to extract the ganoderma lucidum spore powder to obtain ganoderma lucidum spore crude oil, and a second extraction uses theganoderma lucidum spore crude oil extracted by the first extraction and then uses the supercritical carbon dioxide extraction technology to purify the ganoderma lucidum spore crude oil to obtain the ganoderma lucidum spore oil. The ganoderma lucidum spore oil has the effect of protecting the gastric mucosa, can significantly reduce gastric mucosal lesion ulcer and bleeding caused by ethanol, inflammatory pain and other gastric mucosal lesion agents, and delays the occurrence time of an ethanol effect. The ganoderma lucidum spore oil is stable in quality, when the ganoderma lucidum spore oil isused as a raw material of food, health-care food or medicine, a product has the effects of protecting the gastric mucosa and preventing and treating gastric mucosa injury, ulcer and bleeding, and supercritical double extraction, purification and separation can be carried out on line.

Description

technical field [0001] The invention belongs to the field of natural product extraction and traditional Chinese medicine preparation, relates to the technical field of processing and utilization of ganoderma lucidum spores, in particular to a ganoderma lucidum spore oil which has a protective effect on gastric mucosa and a preparation method thereof Background technique [0002] Ganoderma lucidum (Leyss.exFr.) Karst.) is a kind of Ganoderma lucidum in the polyporaceae fungus (Chinese Pharmacopoeia 2015 edition one), sweet in taste and flat in nature, strengthening the body and strengthening the body. Ganoderma lucidum spore powder is a collection of germ cell ganoderma spores produced during the growth and maturity stage of the fruiting body of Ganoderma lucidum. Contains unsaturated fatty acids, sterols, triterpenoids, alkaloids, lactones, proteins and amino acids, glycopeptides and inorganic salts. [0003] The gastrointestinal tract is not only an important digestive org...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/074A61P1/04C11B1/10
CPCA61K36/074A61P1/04C11B1/104A61K2236/37Y02P20/54
Inventor 周岩飞李晔徐伟吴长辉张玉琴方雅玲黄样增林真陈桂秋姚渭溪许建华
Owner 福建仙芝楼生物科技有限公司
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