Synthesis method of tetra (dimethylamino) zirconium
The technology of a dimethylamino group and a synthesis method, which is applied in the field of organic synthesis, can solve the problems of potential safety hazards, dangerous chemical reagents, large waste liquids and the like in the chemical industry, and achieve the effects of shortening the production cycle, improving the safety and reducing the cost.
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Embodiment 1
[0029] Use a vacuum / nitrogen system to replace the gas in the 2 L reaction flask three times. Under a high-purity nitrogen atmosphere, add 1000 mL of n-hexane and 100 g of zirconium tetrachloride to the reaction flask to obtain the first reactant; control the reaction The temperature in the device is -10°C, and 78 g of dimethylamine gas is passed into the first reactant, and reacted at room temperature for 3 hours to obtain the second reactant; the temperature in the reaction device is controlled to be -10°C, and the 163 g of diethylamine was added to the second reactant, and then reacted at room temperature for 3 hours; after the reaction was completed, the reactant was distilled under reduced pressure, and the fraction at 80°C / 0.1 mmHg was collected to obtain 104 g of tetrakis(dimethylamino) ) zirconium, the yield is 91%.
[0030] figure 1 NMR spectrum of tetrakis(dimethylamino)zirconium prepared for this example. NMR: 1 H NMR (300 MHz, C 6 D. 6 ) : 2.98(s, 24H).
Embodiment 2
[0032] Use a vacuum / nitrogen system to replace the gas in the 2 L reaction flask three times. Under a high-purity nitrogen atmosphere, add 1000 mL of n-hexane and 110 g of zirconium tetrachloride to the reaction flask to obtain the first reactant; control the reaction The temperature in the device is -15°C, and 88 g of dimethylamine gas is passed into the first reactant, and reacted at room temperature for 5 hours to obtain the second reactant; the temperature in the reaction device is controlled to be -10°C, and the Add 262 g of di-n-propylamine to the second reactant, and then react at room temperature for 4 hours; after the reaction is completed, the reactant is distilled under reduced pressure, and the fraction at 80°C / 0.1 mmHg is collected to obtain 120 g of tetrakis(dimethylamino ) zirconium, the yield is 95%.
[0033] NMR: 1 H NMR (300 MHz, C 6 D. 6 ) : 2.98(s, 24H).
Embodiment 3
[0035] Use a vacuum / argon system to replace the gas in the 2 L reaction flask three times. Under the high-purity argon atmosphere, add 1000 mL of n-heptane and 100 g of zirconium tetrachloride to the reaction flask to obtain the first reactant ; Control the temperature in the reaction device to be-20°C, feed 81 g of dimethylamine gas into the first reactant, and react at room temperature for 6 hours to obtain the second reactant; control the temperature in the reaction device to be-10°C, Add 247 g of diisopropylamine to the second reactant in the device, and react at room temperature for 4 hours; after the reaction is completed, the reactant is distilled under reduced pressure, and the fraction at 80° C. / 0.1 mmHg is collected to obtain 107 g of tetra(diisopropylamine) Methylamino) zirconium, the yield is 93%.
[0036] NMR: 1 H NMR (300 MHz, C 6 D. 6 ) : 2.98(s, 24H).
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