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Mild anti-corrosion system as well as preparation method and application thereof

A systematic and mild technology, applied in pharmaceutical formulations, cosmetic formulations, cosmetic formulations, etc., can solve problems such as inability to achieve tear-free formulations, achieve high production and application value, improve skin feel, and reduce irritation effects.

Active Publication Date: 2021-11-16
湖北神农芳香大健康产业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims at the defect that the antiseptic system in the prior art has irritating effect on the eyes and cannot realize the true "no-tear formula", and provides a mild antiseptic system and its preparation method and application. The preservatives were screened and compounded to make the components play a synergistic effect, and a mild antiseptic system was prepared, which not only expanded the antibacterial spectrum, significantly improved the antiseptic effect, but also effectively enhanced the mildness and moisturizing of the preservatives Non-toxic, so that it has a good skin feel and will not cause irritation to the eyes, and will hardly cause redness, dryness and pain in the eyes, and realizes a real tear-free formula

Method used

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  • Mild anti-corrosion system as well as preparation method and application thereof
  • Mild anti-corrosion system as well as preparation method and application thereof
  • Mild anti-corrosion system as well as preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0023] This embodiment provides a kind of rose hydrosol comprising antiseptic system, wherein said antiseptic system comprises: polyaminopropyl biguanide 2wt%, cetylpyridinium chloride 1wt%, p-hydroxyacetophenone 0.5wt%, propylene glycol 20wt%, The balance is water.

[0024] The preparation method of the antiseptic system is as follows: under the condition of 50-60°C, dissolve p-hydroxyacetophenone in propylene glycol, then add polyaminopropyl biguanide and cetylpyridinium chloride in sequence, fully dissolve and mix, and obtain the antiseptic system.

[0025] The preparation method of described rose pure dew comprises:

[0026] Step 1. Put the rose petals and water into the distillation kettle after mixing, and carry out distillation extraction under the condition of 50-70°C;

[0027] Step 2, passing the mixture produced by distillation into a condenser for condensation treatment to obtain a distillate;

[0028] Step 3, passing the distillate obtained in step 2 into the oi...

Embodiment 2

[0031] The difference between this embodiment and embodiment 1 is:

[0032] (1) The antiseptic system includes: polyaminopropyl biguanide 1wt%, cetylpyridinium chloride 0.5wt%, p-hydroxyacetophenone 0.3wt%, 1,2-butanediol 10wt%, and the balance is water.

[0033] (2) When the temperature of the pure dew is at 10-15° C., add the above-mentioned anti-corrosion system of 6 wt % of the total mass of the pure dew.

Embodiment 3

[0035] The difference between this embodiment and embodiment 1 is:

[0036] (1) The antiseptic system includes: polyaminopropyl biguanide 3wt%, cetylpyridinium chloride 2wt%, p-hydroxyacetophenone 0.8wt%, 1,2-pentanediol 30wt%, and the balance is water.

[0037] (2) When the temperature of the pure dew is 10-15° C., add the above-mentioned anti-corrosion system of 3 wt % of the total mass of the pure dew.

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Abstract

The invention discloses a mild anti-corrosion system as well as a preparation method and application thereof. The anti-corrosion system is prepared from 1 to 3 weight percent of polyaminopropyl biguanide, 0.5 to 2 weight percent of cetylpyridinium chloride, 0.3 to 0.8 weight percent of p-hydroxyacetophenone, 10 to 30 weight percent of dihydric alcohol and the balance of water. Aiming at the defects that an existing anti-corrosion system has a stimulation effect on eyes and a real tear-free formula cannot be realized, a mild anti-corrosion system is prepared by screening and compounding multiple preservatives with an anti-corrosion function and enabling the components to play a synergistic effect, so that the antibacterial spectrum is expanded, the anti-corrosion effect is remarkably improved, the mild moisture retention of the preservative is also effectively enhanced, and the system has good skin feeling, does not irritate eyes, hardly causes the problems of redness, dryness or pain of the eyes and the like, and realizes a real tear-free formula.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a mild antiseptic system and its preparation method and application. Background technique [0002] Preservatives are an essential class of ingredients in cosmetics and daily chemical cleaning products. Their main function is to protect products from microbial contamination during production or use. There are many existing preservative systems, and the more commonly used one is phenoxyethanol, which has special antibacterial properties against Pseudomonas aeruginosa, and has certain antibacterial effects on both Gram-positive and Gram-negative bacteria, and is in water, Cosmetic ingredients such as white mineral oil and isopropyl palmitate have considerable solubility, low toxicity, and no allergic irritation, so they are widely used. However, research has found that their bactericidal range is limited. For cosmetics with high water content, especially floral water (also known ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/84A61K8/49A61K8/9789A61Q19/00A61Q5/02A61Q19/10A61Q1/14
CPCA61K8/84A61K8/4926A61K8/9789A61Q19/00A61Q5/02A61Q19/10A61Q1/14A61K2800/524A61K2800/805A61K2800/592Y02A50/30
Inventor 汪垠明田伟兰卢正美
Owner 湖北神农芳香大健康产业有限公司
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