Traditional Chinese medicine gel for promoting tissue regeneration and healing ulcer and preparation method thereof

A kind of ulcer gel and gel technology, which is applied in the field of medicine and achieves the effects of suitable fluidity, good spreadability and good compatibility

Pending Publication Date: 2022-03-08
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no report on the traditional Chinese medicine gel w

Method used

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  • Traditional Chinese medicine gel for promoting tissue regeneration and healing ulcer and preparation method thereof
  • Traditional Chinese medicine gel for promoting tissue regeneration and healing ulcer and preparation method thereof
  • Traditional Chinese medicine gel for promoting tissue regeneration and healing ulcer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0035] Method for preparing a muscle gelatin gel, including the following steps:

[0036] 1. Add white peony, angelica, licorice, land, and cork, mix with a proper amount of ethanol, and extract with water decoction method, concentrate dry into a dry cream;

[0037] 2, add loose grass to the appropriate amount of ethanol, 50 ° C water bath, combined with extract, concentrate into the dipper.

[0038] 3, dissolve the dry extract, the purple grazer is dissolved in purified water, spare;

[0039] 4, the blood, glycerol, and ice grind is uniform, then the propylene glycol is grounded uniform, spare;

[0040] 5. Add Carbom to purified water, stir well, and then add triethanolamine tune pH;

[0041] 6. Add the spare material in steps 3, 4 in step 3, 4 in the gel matrix, stir well, to obtain a glyph gel gel;

[0042] Among them, the weight parts of the respective components of the muscular gelatin agent are as described above.

[0043] Preferably, in step 3, first remove the purified wat...

Example Embodiment

[0046] Example 1

[0047] Choice of gel skeleton material:

[0048] (1) Gel formula:

[0049]

[0050]Among them, the gel matrix is ​​selected from the group consisting of matrix Carms 980nf, Carropham 940NF, sodium carboxymethylcellulose, hydroxypropylmethylcellulose, chitosan, and poloxalum, which is formulated according to formulation. The matrix, the formability of the substrate, and two indicators of the meticulousness, thereby preferably a substrate that can be fabricated in a short period of time and a hydrophilicity. The results are shown in Table 1.

[0051] Table 1 Comparison of the performance comparison of different matrix forming gel matrix

[0052]

[0053] It can be seen that the gel prepared by Carropham 980nf is uniform, delicate, gloss, viscous, can be evenly applied.

Example Embodiment

[0054] Example 2

[0055] Preparation of glycologic gel gel. In this example, traditional Chinese medicine drinking pieces: loose, white peony, angelica, licorice, blood exhaust, land, ice, cork, the above Jiuwei Chinese medicine drink film is purchased in Jiangxi Jiangzhong Decoction Co., Ltd. The traditional Chinese medicine gel includes 120 parts by weight of the active ingredient and 1250 parts by weight of the gel matrix, the active ingredient being made of a material of the following weight parts:

[0056] Among them, drug activity is equipped with:

[0057]

[0058] Gel formula:

[0059]

[0060] Preparation:

[0061] 1. Putting white peony, angelica, licorice, land, and cork, baked by 75% ethanol and cooked twice according to the formulation amount.

[0062] 2, add 8 times, 95% ethanol, 50 ° C, extract 3 times, extract 3 times, concentrated under reduced pressure to extract 3 times, concentrated into dip and decompression;

[0063] 3, dissolve the dry extract, the purp...

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Abstract

The invention provides a tissue regeneration promoting and ulcer healing traditional Chinese medicine gel and a preparation method thereof, the tissue regeneration promoting and ulcer healing traditional Chinese medicine gel comprises 100-400 parts by weight of an active component and 200-400 parts by weight of a gel matrix, and the active component is prepared from the following raw materials in parts by weight: 10-50 parts of lithospermum, 10-50 parts of angelica dahurica, 30-100 parts of angelica sinensis, 30-100 parts of liquorice, 10-40 parts of dragon's blood, 10-50 parts of sanguisorba officinalis, 10-20 parts of borneol and 1-10 parts of golden cypress. According to the traditional Chinese medicine preparation, lithospermum, angelica dahurica, angelica sinensis, liquorice, dragon's blood, sanguisorba officinalis, borneol and golden cypress are adopted for compatibility, the effects of detoxifying, healing sore, nourishing and activating blood, removing slough and promoting granulation are achieved, the gel matrix is appropriate in fluidity, easy to spread, good in skin affinity and good in compatibility with a traditional Chinese medicine compound extracting solution, medicine can be slowly and stably released, and the curative effect is good. The bioavailability of the medicine is favorably improved. Through clinical verification, the tissue regeneration and ulcer healing traditional Chinese medicine gel has the effects of detoxifying, healing sore, nourishing blood, activating blood, removing slough and promoting tissue regeneration.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine gel for promoting regeneration and healing ulcers and a preparation method thereof. Background technique [0002] With the acceleration of population aging in my country, the number of patients with skin ulcers is increasing step by step. In addition to skin ulcers directly caused by burns, scalds, and mechanical trauma, they often appear as complications of diseases such as diabetes, arteriosclerosis, and cardiovascular and cerebrovascular diseases. Due to its high incidence rate, it is difficult to recover in a short period of time, which makes the process of disease treatment more difficult for patients. Chronic skin ulcer (CSU), also known as refractory ulcer, is a common and frequently-occurring disease in surgical clinics. It includes vascular ulcers, pressure ulcers, radiation ulcers and infectious ulcers. Studies in recent years have sho...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K36/889A61K36/896A61K47/32A61P17/02A61K31/045
CPCA61K9/06A61K9/0014A61K47/32A61K36/30A61K36/232A61K36/484A61K36/889A61K36/896A61K36/739A61K31/045A61K36/756A61P17/02A61K2236/333A61K2236/51A61K2236/39A61K2300/00
Inventor 徐玲霞孙朋颜冬梅李斌王飞
Owner JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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