Vitamin K2-containing pharmaceutical composition for improving cardiovascular calcification as well as preparation method and application thereof

A composition and vitamin technology, applied in the direction of drug combination, medical preparations containing active ingredients, cardiovascular system diseases, etc., can solve the problems such as the role of reversing calcification is not taken seriously, the biological activity is reduced, and intestinal absorption is difficult, etc. Achieve the effects of improving the body's immunity, improving vascular calcification, and avoiding body damage
CN114748486APending Publication Date: 2022-07-15NANJING SHENGDE INST OF BIOTECHNOLOGY CO LTD +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANJING SHENGDE INST OF BIOTECHNOLOGY CO LTD
Publication Date
2022-07-15

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Abstract

The invention provides a pharmaceutical composition containing vitamin K2 for improving cardiovascular calcification, which is composed of a composition I, a composition II and a composition III in a mass ratio of (0.1-5): (0.01-0.5): (100-500). The invention also provides a preparation method and application of the pharmaceutical composition. The pharmaceutical composition can comprehensively prevent and block cardiovascular calcification, is especially suitable for reversing cardiovascular calcification symptoms caused by taking statins, and provides a daily support and protection effect for heart health at the same time. The pharmaceutical composition disclosed by the invention has the advantages of stable active ingredients, high bioavailability, strong targeting property and no side effect, and can achieve the purposes of prevention and treatment at the same time.
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Description

technical field

[0001] The invention relates to the technical fields of medicine, health care products and food, in particular to a kind of vitamin K containing 2 A pharmaceutical composition for improving cardiovascular calcification and a preparation method and application thereof. Background technique

[0002] Vascular calcification refers to the inappropriate biological calcification that occurs in the soft tissue of the cardiovascular system, and is a pathological change in which calcium salts are deposited in the arterial wall tissue. It is prevalent in various diseases such as atherosclerosis, diabetes, kidney disease, aging, and systolic hypertension, which can easily lead to myocardial infarction and cerebral apoplexy. Previous studies believed that vascular calcification is a passive, degenerative, and inevitable terminal process, but recent clinical and basic research results show that vascular calcification is similar to the process of bone development and carti...

Claims

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