Dichloroacetic acid diisopropylamine oral preparation and its preparation process-treatment of liver function injury

Abstract

An orally applied disotat for treating hepatic dysfunction is prepared from disotat as active component and proper auxiliaries. It may be tablet, coated tablet, effervescent tablet, enteric tablet, chewing tabet, capsule, softgel, pill, etc.

Description

technical field [0001] The present invention relates to a kind of medicine preparation and preparation technology thereof, specifically, a kind of chemical name is dichloroacetic acid and N-(1-methylethyl)-2-propanamine compound, and its structural formula is Its molecular formula is C 6 h 15 N·C 2 h 2 Cl 2 o 2 , an oral preparation of diisopropylamine dichloroacetate, which has a molecular weight of 230.13, and a preparation process thereof. technical background [0002] The liver is like a huge "chemical factory" in the human body. It plays a very important role in metabolism, bile production, detoxification, blood coagulation, immunity, heat production, and water and electrolyte regulation, as shown in: [0003] 1. Metabolic function: [0004] 1. Sugar metabolism. After the starch and sugar in the diet are digested and turned into glucose and absorbed by the intestine, the liver can synthesize it into liver glycogen and store it in the liver. The liver regulates...

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Problems solved by technology

[0021] 4. This product can hinder the activity of synthetic cholesterol rate-limiting enzyme (HMGCoA reductase)

In this case, although the effect of diisopropylamine dichloroacetate is not as strong as that of ACTH or cortisone, the drug effect lasts for a long time. Clinically, it can improve mood, increase appetite, clear mind, and subside muscle pain.