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Solid oral preparation of sodium copper chlorophyllin and its preparing method

A technology of sodium copper chlorophyll and solid preparation, applied in the directions of pill delivery, block delivery, blood diseases, etc., can solve the problems of insignificant treatment effect and the like

Inactive Publication Date: 2003-09-03
黄羿
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] At present, small doses of sodium copper chlorophyllin have been used to treat leukopenia, and have certain curative effects on leukopenia caused by chemotherapy and radiotherapy; in addition, small doses are used for acute and chronic hepatitis, persistent hepatitis, etc. administration, the therapeutic effect is not significant

Method used

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Examples

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Effect test

Embodiment Construction

[0032] 1. The tablets containing sodium copper chlorophyllin as the active ingredient have the following formula composition: based on the prescription amount of each tablet, the main drug sodium copper chlorophyllin contains 50mg, 75mg, and 100mg respectively; the auxiliary materials contain 85mg of starch, 40mg of dextrin, and sucrose powder 45mg, magnesium stearate 0.6mg.

[0033] 2. Sustained-release tablets containing sodium copper chlorophyllin as the active ingredient have the following formula: based on the prescription amount per tablet, the main drug sodium copper chlorophyllin is 50mg; the excipients contain 40mg of polyacrylic resin II, 75mg of starch, and 40mg of hypromellose , povidone 45mg, 6% starch slurry and magnesium stearate amount.

[0034] 3. The capsule containing sodium copper chlorophyllin as the active ingredient has the following formula: based on the prescription amount of each capsule, the main drug sodium copper chlorophyllin is 50 mg; the auxilia...

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Abstract

An orally applied solid medicine of chlorophyll copper sodium in the form of tablet, slow-releasing tablet, or particle for treating cytopenia, thrombo cytopenia and bone marrow arrest is prepared from the chlorophyll copper sodium as active component and filler through wet process.

Description

technical field [0001] The present invention relates to an oral solid preparation with sodium copper chlorophyllin as an active ingredient and a preparation method thereof. Experiments have shown that high-dose oral copper sodium copper chlorophyllin preparation has the effect of treating blood cell reduction, bone marrow suppression and thrombocytopenia caused by chemotherapy drugs and other causes. effect. Background technique [0002] Sodium copper chlorophyllin is a dark green powder with metallic luster, odorless or slightly ammoniacal, soluble in water, slightly soluble in alcohol and chloroform, almost insoluble in oil and petroleum ether; its aqueous solution is blue-green, transparent, non-toxic Precipitation, the pH value of 1% aqueous solution is 9.5-10.2. [0003] 1. Production route [0004] (1) Copperization and saponification process [0005] Using clover, nettle, alfalfa, spinach and other plant leaves or dried silkworm excrement as raw materials, first ex...

Claims

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Application Information

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IPC IPC(8): A61K9/16A61K9/20A61K31/555A61P7/00
Inventor 黄羿
Owner 黄羿
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