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Simple production process for zinc citrate, zinc lactate, ferrous citrate and ferrous lactate

A technology of ferrous lactate oral liquid and ferrous citrate, which is applied in the simple production process of ferrous citrate, ferrous lactate oral liquid, zinc citrate, and zinc lactate, can solve the problem of poor absorption efficiency and unstable ferrous , easy to be oxidized and other problems, to achieve the effect of good anti-oxidation performance, guaranteed purity and low price

Inactive Publication Date: 2005-07-13
李恕勤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For a long time, the commonly used iron supplement is ferrous sulfate, which has low bioavailability and side effects
Because ferrous iron is unstable and easily oxidized, it is difficult to produce and store, so the production process is complicated and the cost is high
The commonly used oral zinc supplement is zinc gluconate, because it is solid, it is difficult to administer to children and infants, and the absorption efficiency is poor

Method used

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  • Simple production process for zinc citrate, zinc lactate, ferrous citrate and ferrous lactate
  • Simple production process for zinc citrate, zinc lactate, ferrous citrate and ferrous lactate
  • Simple production process for zinc citrate, zinc lactate, ferrous citrate and ferrous lactate

Examples

Experimental program
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Effect test

Embodiment 1

[0012] see figure 1 , use 1.2 kg of zinc oxide as raw material, add 2 kg of water, add 3 kg of hydrochloric acid or sulfuric acid with a concentration of 30%, and form zinc chloride or zinc sulfate through chemical reaction, make it fully soluble in the aqueous solution, and then add a concentration of 10% 20 kilograms of sodium carbonate solution, generate zinc carbonate precipitate through chemical displacement reaction, make solution final pH value be 8. Filter the sediment, put it into the reaction kettle that is dissolved in 27 kilograms of distilled water by 3 kilograms of solid edible citric acid and be diluted into the reaction kettle that concentration is 10% citric acid aqueous solution after washing twice with the water after the fine filter, in Fully stir at room temperature to form a zinc citrate solution, then add 950 kg of distilled water, and then add sweeteners and preservatives to obtain an oral solution of zinc citrate containing 10 mg of zinc per 10 ml. In...

Embodiment 2

[0016] see figure 1 , use 1.2 kg of zinc oxide as raw material, add 2 kg of water, add 3 kg of hydrochloric acid or sulfuric acid with a concentration of 30%, and form zinc chloride or zinc sulfate through chemical reaction, make it fully soluble in the aqueous solution, and then add a concentration of 10% 20 kilograms of sodium carbonate solution, generate zinc carbonate precipitate through chemical displacement reaction, make solution final pH value be 8. Filter the precipitate, wash it twice with finely filtered water, put it into a reaction kettle equipped with a 10% lactic acid aqueous solution diluted with 3 kg of lactic acid dissolved in 18 kg of distilled water, and fully Stir to form a zinc lactate solution, then add 950 kg of distilled water, and then add sweeteners and preservatives to obtain an oral solution of zinc lactate containing 10 mg of zinc per 10 ml, and finally pass the test and fill it into a 5-600 ml capacity In the bottle, a small measuring cylinder i...

Embodiment 3

[0020] see figure 2 , use 7.5 kg of ferrous sulfate purified by filtration or recrystallization as raw material, add 100 kg of finely filtered water, stir well to fully dissolve ferrous sulfate, and then filter it into a closed reaction kettle , the upper part of the reactor was protected with carbon dioxide gas. Another 5 kg of 10% sodium carbonate solution made from edible sodium carbonate is added to the reaction kettle, and the iron carbonate precipitate is generated through stirring. Make the pH of the solution 10. Add the ferric carbonate precipitate after the above-mentioned pressure filtration in the reaction kettle diluted with 8 kilograms of solid edible citric acid and 72 kilograms of distilled water into a 10% citric acid solution, make the temperature gradually rise to 50 ° C, stir for 20 minutes, when When the solution pH value was 6, stop stirring and make ferrous citrate solution. Then add 170 kilograms of distilled water, then add sweetener and preservativ...

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Abstract

The present invention relates to the simple production process of zinc citrate, zinc lactate, ferrous citrate and ferrous lactate oral liquid, and features that the zinc citrate, zinc lactate, ferrous citrate and ferrous lactate oral liquid is produced through the direct chemical reaction between organic acid and zinc carbonate or ferric carbonate while adding protect CO2 gas to prevent ferrous ion from being oxidized. The present invention can produce cheap zinc replenishing and iron replenishing oral liquid easy to be absorbed by human body and with high stability, high purity and no side effect.

Description

technical field [0001] The invention relates to a production process of oral liquid, in particular to a simple production process of zinc citrate, zinc lactate, ferrous citrate and ferrous lactate oral liquid. Background technique [0002] Iron is an important raw material for the production of hemoglobin in the human body. Hemoglobin is the main functional substance in red blood cells and is responsible for the transportation and metabolism of oxygen in the body. Therefore, the lack of iron will affect human behavior and immune function. According to the survey, the incidence of iron deficiency anemia in children in my country is relatively high. Zinc is an indispensable trace element for the human body. Zinc directly affects children's intellectual development, so it is particularly important for children's development or long-term zinc supplementation. For a long time, the commonly used iron supplement is ferrous sulfate, which has low bioavailability and side effects. ...

Claims

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Application Information

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IPC IPC(8): A61K31/191A61P3/02A61P7/06
Inventor 李恕勤
Owner 李恕勤
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