Skin treatment compositions containing copper-pigment complexes

Abstract

A therapeutic method is described in which copper is delivered into the skin as a complex with sodium chlorophyllin. Sodium copper chlorophyllin is encapsulated in suitable lecithin-type liposomes, containing a high concentration of linoleic acid and having diameters in the range 150-350 nanometers. The method provides therapeutic benefits in the treatment of environmentally-induced premature skin aging, excessively oily skin, acne and acne-related skin disorders, acne-rosacea, and also stimulates the natural tanning response of skin to sunlight and other ultraviolet-containing radiation.

Description

FIELD OF THE INVENTION [0001] This invention is directed toward therapeutic substances and methods for treating skin problems caused by environmental factors or chronic skin pathologies. BACKGROUND OF THE INVENTION [0002] There are important roles for copper in regulating various functions and processes in the human body, including within the skin. Copper is part of an enzyme that regulates energy metabolism, cytochrome c oxidase, and is also essential for the repair of skin tissues by virtue of its role in the cross-linking of elastin and collagen by lysyl oxidase. Copper is a key part of the skin's antioxidant protection system, for removal of superoxide radicals by the antioxidant SOD (superoxide dismutase). Studies have shown that when copper salts are applied directly to the skin in an aqueous solution there is little or no significant benefit. Moreover, the cuprous copper ion (Cu+2) is a catalyst for activating molecular oxygen and is therefore a potential pro-oxidant. It is t...

AI Technical Summary

Benefits of technology

"The patent text describes a method for delivering copper to the skin to protect against oxidative damage and promote skin repair. The copper is complexed with plant pigments and chromophores, which provide antioxidant protection and enhance skin renewal. The method also involves using a specific type of lecithin, called high linoleic acid lecithin, which has been found to reduce acne symptoms. The copper is delivered in a liposomal dispersion, which allows for controlled release of the copper based on pH differences. Overall, the method provides a safe and effective way to protect the skin from environmental stress and promote skin health."

Problems solved by technology

The intensity of oxidative risks from our environment is increasing; this is particularly significant for skin because of its direct exposure to the environment.

Damaged or incomplete cross-linking of collagen and elastin can reduce the tensile strength of connective tissue.

It has been suggested that seborrheic inflammatory conditions also play a role in excess oiliness of skin, producing a cosmetically unattractive shiny appearance.