Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for Separation of Lactic Acid Component from Lactic Acid Fermentation Liquor, and Separation Apparatus

a technology of lactic acid and fermentation liquor, which is applied in the direction of solvent extraction, biomass after-treatment, separation process, etc., can solve the problems of increasing the number of steps of further reagents, the need to remove alcohols, and the possibility of incorporation of concomitant chemical substances or impurities, so as to achieve simple process and low cost

Inactive Publication Date: 2009-04-09
KANSAI CHEM ENG CO LTD +1
View PDF9 Cites 13 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0008]In the separation method using electrodialysis, there are a concern about the life and fouling of the membranes used. Furthermore, a lactic acid fermentation liquor may contain not only lactic acid, but also organic components such as proteins and surfactants and inorganic components such as salts of phosphoric acid, sulfuric acid, acetic acid, and citric acid, as nutrients and medium components for lactic acid bacteria. Thus, contamination of the membranes is severer, and maintenance of the membranes leads to an increase in the cost. In addition, salts derived from medium components in the fermentation liquor, as well as the lactate salts, are concentrated by dialysis, and thus the precision of separation and the purity of the lactate salt are lowered.
[0009]According to the present invention made in view of these problems, it is intended to provide a method for separating a lactic acid component from a lactic acid fermentation liquor, which does not require reaction reagents, which cause an increase in the cost or incorporation of impurities, or consumables such as separation membranes, which are not contained in a final product, and which includes a reduced number of steps.
[0042]According to the present invention, a lactic acid component can be separated from a lactic acid fermentation liquor with a simple process, at a low cost, and without incorporation of impurities.

Problems solved by technology

Thus, except for the case of obtaining lactic acid esters or calcium lactate as a final target product, the further reagents may be used with increase in the number of steps, the cost of agents, and the possibility of incorporation of concomitant chemical substances or impurities.
The resultant alcohols are required to be removed since alcohols cannot be contained in the final product.
In the separation method using electrodialysis, there are a concern about the life and fouling of the membranes used.
Thus, contamination of the membranes is severer, and maintenance of the membranes leads to an increase in the cost.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for Separation of Lactic Acid Component from Lactic Acid Fermentation Liquor, and Separation Apparatus
  • Method for Separation of Lactic Acid Component from Lactic Acid Fermentation Liquor, and Separation Apparatus

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0119]In a lactic acid fermentation liquid medium that contained 3.5 wt % of standard medium M17 (manufactured by Difco Laboratories) for streptococcus, supplemented with 14 wt % of glucose, lactic acid bacteria (streptococcus bacteria) were subjected to lactic acid fermentation in suspension culture while the pH of the medium was adjusted with ammonia to near 6, to obtain 20 g of lactic acid fermentation liquor (pH 6) in which the concentration of ammonium lactate was 10 wt %. The cells of bacteria were removed in advance from the lactic acid fermentation liquor by centrifugal separation. The pH of the lactic acid fermentation liquor was adjusted to 4.8 by addition of sulfuric acid. Subsequently, 50 ml of xylene was added thereto, and the mixture was heated at 130° C. with agitation in a reflux state. One hour later, the agitation was stopped and the mixture was allowed to stand while continuing heating at 130° C., to separate it into two layers. When the upper layer was collected ...

example 2

[0120]As in Example 1 above, 20 g of lactic acid fermentation liquor (pH 6) was obtained in which the concentration of ammonium lactate was 10 wt %. The cells of bacteria were removed from the lactic acid fermentation liquor as in Example 1. The pH of the lactic acid fermentation liquor was adjusted to 2.5 by addition of sulfuric acid. Subsequently, 50 ml of xylene was added thereto, and the mixture was heated at 130° C. with agitation in a reflux state. One hour later, the agitation was stopped and the mixture was allowed to stand while continuing heating at 130° C., to separate it into two layers. When the upper layer was collected and cooled down to room temperature, precipitation was observed. The precipitation was due to lactic acid, and the yield of the extraction was 20% (see Table 1 below).

example 3

[0123]As in Example 1 above, 20 g of lactic acid fermentation liquor (pH 6) was obtained in which the concentration of ammonium lactate was 10 wt %. The cells of bacteria were removed from the lactic acid fermentation liquor as in Example 1. The pH of the lactic acid fermentation liquor was adjusted to 4.8 by addition of sulfuric acid. Subsequently, 50 ml of xylene was added thereto, and the mixture was heated to 100° C. with agitation. A vapor was condensed, water from which was removed, and then refluxed, and about 17 g of water was thus removed over approximately 2 hours. Subsequently, the mixture was heated to 130° C. One hour later, the agitation was stopped and the mixture was allowed to stand, to separate it into two layers. When the upper layer was collected and cooled down to room temperature, precipitation was observed. The precipitation was due to lactic acid, and the yield of the extraction was 20% (see Table 2 below).

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
pHaaaaaaaaaa
temperatureaaaaaaaaaa
temperatureaaaaaaaaaa
Login to View More

Abstract

A lactic acid component (e.g., lactic acid or oligo (lactic acid)) can be obtained by extraction from a lactic acid fermentation liquor with a pH of 4.8 or less, using at least one solvent selected from the group consisting of toluene, xylene, mesitylene, ethylbenzene, methanol, ethanol, propanol, butanol, and mineral spirit. Furthermore, oligo (lactic acid) can be obtained, by heating a lactic acid fermentation liquor with a pH of 4.8 or less under reduced pressure, and washing, with water, the fermentation liquor containing a produced oligo (lactic acid). Hence, a method is provided for separating a lactic acid component from a lactic acid fermentation liquor, which is free from incorporation of impurities and which includes simple steps.

Description

TECHNICAL FIELD[0001]The present invention relates to methods for separating a lactic acid component from a lactic acid fermentation liquor, and apparatuses for the same.BACKGROUND ART[0002]Conventionally, a lactic acid component is separated from a lactic acid fermentation liquor using, for example, a method for collecting a lactic acid component in the form of a lactic acid ester, a method for collecting a lactic acid component in the form of calcium lactate, or a method for separating a lactic acid component by electrodialysis.[0003]As the method for collecting a lactic acid component in the form of a lactic acid ester, a method is disclosed in which a lactic acid ester is synthesized by adding butanol or pentanol to ammonium lactate generated by fermentation, and collected by distillation (for example, Japanese Laid-Open Patent Publication No. 6-311886).[0004]As the method for collecting a lactic acid component in the form of calcium lactate, a method is disclosed in which lacti...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): C12P7/56C12M1/02
CPCB01D11/0488C07C51/48B01D11/0492C07C59/08Y02P20/582C12P7/56B01D11/04C12P7/62
Inventor UYAMA, HIROSHINODA, HIDEOTERADA, TAKAHIKO
Owner KANSAI CHEM ENG CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com