8 results about "Glucosamine hcl" patented technology

The utility model relates to the technical field of glucosamine hydrochloride, in particular to glucosamine hydrochloride post-processing equipment which comprises a coating barrel with an opening in the top, the coating barrel is connected with the lower end of a powder storage barrel, a plurality of discharging holes are formed in the bottom of the powder storage barrel, a baffle is arranged below the powder storage barrel, and a plurality of discharging holes are formed in the bottom of the powder storage barrel. A through hole matched with the discharging hole is formed in the baffle, the middle of the baffle is connected to the middle of the circumferential side face of a rotating shaft in a sleeving mode, a plurality of stirring rods are installed at the lower end of the circumferential side face of the rotating shaft, a scraper is installed on the circumferential side face of the rotating shaft on one side of the stirring rods, and the upper end of the rotating shaft penetrates through the top of the containing plate to be connected with the driving end of a rotating motor; due to the fact that the discharging holes are evenly distributed in the bottom of the powder storage barrel, powder can be evenly added, and due to the fact that the scraping plate is arranged, the scraping plate can be driven to rotate under driving of the rotating motor, scraping of the inner wall of the coating barrel is achieved, and the situation that in the coating process, the powder is prone to adhering to the inner wall of the coating barrel, and follow-up cleaning wastes time and labor is avoided.

The invention provides a glucosamine hydrochloride capsule and a preparation method thereof, the capsule content comprises the following components in parts by weight: 240 parts of glucosamine hydrochloride, 50-60 parts of starch and 2-7 parts of hydroxypropyl cellulose; the glucosamine hydrochloride capsule prepared by controlling the particle sizes of the glucosamine hydrochloride and the starch within a specific range and using a specific adhesive is high in dissolution rate (the dissolution rate in four dissolution media for 45 minutes is not lower than 85%), and the dissolution rate is stable after the glucosamine hydrochloride capsule is placed for 24 months for a long time.

The present application relates to the field of biotechnology, and particularly relates to a composition, a culture medium and application thereof in intestinal organoid culture. The present application first applies glucosamine hydrochloride to the culture of intestinal organoids, which can effectively promote organ proliferation and differentiation, and significantly increase the number of organ formation. On this basis, the present application constructs a three-dimensional culture system for postpartum neonatal, childhood and adult stages, and realizes the precise construction of mouse intestinal organoids at different development stages by combining dynamic regulation of extracellular matrix and optimization of growth factor combinations, thereby providing an in-vitro model covering multiple time sequences for intestinal development mechanism research and disease modeling.

The application discloses a multi-component synovitis treatment composition based on repairing cartilage tissue and application thereof, and relates to the technical field of biological medicine, and the composition is composed of glucosamine hydrochloride, chondroitin sulfate, dimethyl sulfone and graded molecular weight sodium hyaluronate; the application precisely compounding the graded molecular weight sodium hyaluronate with the glucosamine hydrochloride, the chondroitin sulfate and the dimethyl sulfone according to weight parts, constructs a gradient slow-release and target delivery system of synovitis lesions, specifically inhibits the activity of hyaluronidase in the inflammatory joint cavity by using the dimethyl sulfone, greatly reduces the degradation of the sodium hyaluronate, prolongs the residence time of the active ingredients at the lesion site, realizes immediate analgesia and relieves joint stiffness by quickly forming a lubricating protective film by the high molecular weight sodium hyaluronate, the medium and low molecular weight sodium hyaluronate penetrates the synovial membrane barrier and carries the cartilage repair components to enrich in the cartilage defect area, and the synergistic effect of the components is realized.

1. Name of the product in this design: Packaging Box (Glucosamine Hydrochloride Capsules). 2. Intended use of this design: pharmaceutical packaging box. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention relates to the technical field of analysis, in particular to an analysis method of glucosamine hydrochloride. The invention provides an analysis method of glucosamine hydrochloride, which can accurately, sensitively and quickly detect the content of glucosamine hydrochloride in a product (such as oral liquid), and can be used for realizing quality control on the product containing glucosamine hydrochloride.

The invention relates to the technical field of preparation of sea-buckthorn peel residue degraded polysaccharide, in particular to sea-buckthorn peel residue degraded polysaccharide as well as a preparation method and application thereof. The sea buckthorn peel residue degraded polysaccharide comprises the following monosaccharides: mannose, glucosamine hydrochloride, rhamnose, glucuronic acid, galacturonic acid, glucose, galactose, xylose and arabinose. The method comprises the following steps: extracting and collecting hippophae rhamnoides fruit peel residue crude polysaccharide by taking hippophae rhamnoides fruit peel residue as a raw material through an ultrasonic extraction method, and then degrading the hippophae rhamnoides fruit peel residue crude polysaccharide by adopting a free radical degradation method based on an ascorbic acid-hydrogen peroxide system to obtain the degraded hippophae The prepared sea-buckthorn pericarp residue degraded polysaccharide has the effects of scavenging free radicals, inhibiting the activity of alpha-amylase and inhibiting the activity of alpha-glucosidase, and all the effects after degradation are remarkably improved.

The present invention discloses a multi-component synovitis therapeutic composition based on cartilage tissue repair and a use thereof, relating to the technical field of biomedicine. The composition comprises glucosamine hydrochloride, chondroitin sulfate, dimethyl sulfone, and graded molecular weight sodium hyaluronate. By compounding these components in precise parts by weight, the present invention constructs a gradient sustained-release and targeted delivery system for synovitis lesions. Dimethyl sulfone specifically inhibits hyaluronidase activity in the inflamed joint cavity, significantly reducing sodium hyaluronate degradation and prolonging the retention time of each active ingredient at the lesion site. High molecular weight sodium hyaluronate rapidly forms a lubricating protective film to achieve immediate analgesia and relieve ankylosis, while medium- and low-molecular-weight sodium hyaluronate penetrates the synovial barrier and carries cartilage repair components to the cartilage defect area, thereby achieving synergistic enhancement and comprehensively improving synovitis treatment efficacy.