The invention discloses a breeding method of a Xiaoxi populus euphratica variety, which adopts Xiaoxi populus euphratica hybrid populus as a variety for cutting breeding, and comprises the following steps: collecting cuttings, treating the collected cuttings, cutting in a greenhouse and carrying out tending management. When the cuttings are treated, the lower ends of the cuttings are immersed in an IBA solution, a good rooting effect is achieved, meanwhile, the upper ends of the cuttings are smeared with a wound healing agent, it is guaranteed that the cuttings are not infected by germs in the growth and reproduction process, and the survival rate of cuttage of the populus euphratica var. Diversifolia is increased to a certain degree. The Populus euphratica bred by the method is short in seedling time, developed in root system, excellent in quality and stable in shape, and can thrive after being transplanted to saline-alkali soil.