The present invention belongs to the field of probiotics and their application technology, and is specifically related to a strain of
Lactobacillus johnsonii XY9 and its application in the preparation of hypoglycemic and anti-aging food and
medicine. The present invention separates and purifies a strain of
Lactobacillus johnsonii XY9 from a fecal sample of a healthy adult in Guangdong, China, and the strain has excellent
protease activity, can produce and secrete γ-
aminobutyric acid, can inhibit α-
glucosidase activity, can remove
DPPH free radicals, and has excellent
cellulase activity. Therefore, the strain has the function of promoting
digestion and absorption of
protein food, improving
protein allergy, anti-depression and improving sleep, hypoglycemic and
weight loss, anti-oxidative whitening, anti-aging, anti-inflammatory, promoting the absorption of
cellulose, improving
constipation and other functions, and can be used in the fields of hypoglycemic and anti-aging, with important application value and economic value.