The invention relates to the technical field of false tooth maintenance, and discloses a multi-cabin separation type circulating cleaning and disinfecting device for false tooth maintenance, the multi-cabin separation type circulating cleaning and disinfecting device for false tooth maintenance comprises a false tooth maintenance box body, a partition plate, a water storage cabin, a cleaning cabin and a disinfecting cabin, a fixing block is fixedly connected to the inner wall of the right side of the cleaning cabin, and a groove is formed in the left side face of the fixing block; the inner wall of the left side of the cleaning cabin is fixedly connected with an electric cylinder, the right side face of the electric cylinder is provided with a piston rod, and the end, away from the electric cylinder, of the piston rod is fixedly connected with a second motor. A second output shaft is arranged on the right side face of the second motor, a rotating shaft is fixedly connected to the end, away from the second motor, of the second output shaft, and a cleaning brush is arranged at the end, away from the second output shaft, of the rotating shaft. By means of the structure, the cleaning effect on the false tooth can be improved.