Relating to the field of animal medicines, the invention provides a compound propolis composition for promoting pig growth and fattening as well as its preparation method. The composition and its preparation method in the invention are shown as the following: (1) respectively subjecting each component in a formula to superfine comminution and then to sieving through a sieve of 700 meshes; (2) weighing, by weight, 15-35 parts of propolis, 10-30 parts of gelsmium elegans, 10-45 parts of scorch-fried three immortals, and 15-40 parts of dried orange peels, and mixing them for 5-10min to a uniform state; (3) weighing, by weight, 15-35 parts of rhizoma atractylodis, 10-35 parts of betel nuts, 10-35 parts of licorice, 15-40 parts of dried ginger, and 15-35 parts of radix astragali, and mixing them for 5-10min to a uniform state; and (4) combining the compositions prepared in step (2) and (3), and continuing to mixing them for 10-15min to a uniform state, thus obtaining the compound propolis composition. The compound propolis composition of the invention has the advantages of reasonable formula, simple preparation, no toxic or side effect, no pollution, no medicine residue, no drug resistance, superfine comminution, high bioavailability, and very obvious curative effect. There is clinical evidence that the compound propolis composition in the invention has specific efficacy in promoting growth and fattening of livestock.