Blood serum copper, zincium and iron 5-br-padcap even phase automatic analysis method and liquid stabilizing reagent

A 5-br-padcap and serum copper technology, applied in the fields of medicine and biochemistry, can solve the problems of slow dissociation speed of serum copper, long color development time, and unsuitability for routine analysis
CN101097220AInactive Publication Date: 2008-01-02WENZHOU MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
WENZHOU MEDICAL UNIV
Publication Date
2008-01-02
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention relates to 5-Br-PADCAP even phase automatic analysis method and liquid stabilizer of serum copper, zinc, iron; it can be widely used in medicine and biochemistry technique filed, which is characterized in that: by serum copper, zinc, iron and quick decomposition of conjugated protein and application of hematocyanin stabilization technology with protein dissociation agent, the copper, zinc, iron in serum is cleavaged from the conjugated protein quickly on condition of even phase, and chromogenic reaction is happened with water soluble pyridylazo dye 5-Br-PADCAP under condition that surface activator, content measurement of copper, zinc, iron in sample can be realized on automatic analyzer in measurement mode of two-point end method. The liquid measurement agent with the method is stable, convenient, and capability of anti-interference is strong, without pollution to tube of automatic analyzer, it fits for batch automatic detection of copper, zinc, iron especially.
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Description

technical field

[0001] The invention relates to a 5-Br-PADCAP homogeneous automatic analysis method for serum copper, zinc and iron and a liquid type latent reagent, which can be widely used in the technical fields of medicine and biochemistry. Background technique

[0002] Copper, zinc, and iron are trace elements necessary for the human body, and they have many physiological functions in the human body. Numerous clinical data show that the occurrence of certain diseases is closely related to the content of copper, zinc, and iron in the human body. For example, elevated serum copper can be seen in hyperthyroidism, leukemia, Hodgkin's disease, hemochromatosis, and biliary cirrhosis , typhoid fever, tuberculosis, pernicious anemia, rheumatism and malignant tumors and other diseases, decreased serum copper can be seen in infant anemia, infant malnutrition, hepatolenticular degeneration and other diseases. Elevated serum zinc is common in acute zinc poisoning caused by industr...

Claims

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