Application of lactoferrin in preparing medicament for preventing and controlling disease caused by human rotavirus

Abstract

The invention discloses an application of lactoferrin in the drug to prevent human rotavirus, which is characterized by the following: the medium effective dose of lactoferrin is 278. 45+-12. 88mu g / mL; the medical treating index is 17. 98; the resource is wide and the cost is inexpensive, which can prevent HRV, therefore paving basis for new drug sieving.

Description

(1) Technical field

[0001] The invention relates to the application of lactoferrin in the preparation of medicines for preventing and treating diseases caused by human rotavirus. (2) Background technology

[0002] Lactoferrin (Lactoferrin, LF) was first isolated from milk by Groves in 1960. It is red because it combines with iron, so it is called "globin". At the beginning of its discovery, LF was considered to be a protein related to iron transport and storage, so it was also called lactotransferrin. Further studies have shown that LF is a glycoprotein with a molecular weight of 70-80kD, which is widely present in exocrine fluids such as milk, saliva, and tears, or plasma, and neutrophils. The content of LF in milk, especially colostrum is very high, for example, the mass concentration of LF in bovine colostrum is 1g / L. In-depth research has found that LF is a protein with multiple biological functions. It not only participates in the transport of iron, but also has antib...