Externally used preparations with functions of anti-inflammation, relieving itching and sterilization disinfection, and method for preparing the same

An external preparation, disinfection and sterilization technology, applied in the directions of medical preparations containing active ingredients, topical antibacterial agents, active ingredients of hydroxyl compounds, etc., to achieve the effects of good safety, rapid sterilization and remarkable effect

Active Publication Date: 2008-04-02
西藏海容唐果药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For skin itching caused by damp heat accumulation or blood heat and wind dryness; neurodermatitis, warm rash, and itchy skin diseases such as hands, feet, tinea corporis and psoriasis caused by various fungi, bacteria, and microbial infections, see above Syndrome, but

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] composition:

[0036] Rhubarb 99g Turmeric 80g Sulfur 70g Scutellaria baicalensis 5g

[0037] licorice 8g borneol 6.9g menthol 0.1g dexamethasone acetate 0.45g

[0038] Fluocinolone acetate 0.75g Glycerin 60g Stearic acid 90g Triethanolamine 30g

[0039] Liquid paraffin 100g Paraffin 70g Ethylparaben 12g Purified water 370g

[0040] Preparation:

[0041] Grind the above-mentioned dry effective medicinal ingredients rhubarb, turmeric, sulfur, baicalin, and licorice that meet the requirements of the Pharmacopoeia into ultra-fine powders with a particle size of 75-90um, and mix them with borneol, menthol, dexamethasone acetate, and fluocinolone acetate by weight. Than grind evenly. Glycerin, stearic acid, triethanolamine, liquid paraffin, paraffin, ethylparaben and purified water are heated and melted in a container, stirred evenly and condensed to obtain an ointment-type base material. Add the medicinal powder into the matrix and stir well to make 1000g ointment.

Embodiment 2

[0043] composition:

[0044] Rhubarb 96g Turmeric 75g Sulfur 60g Scutellaria baicalensis 13g

[0045] Licorice 0.1g Borneol 5g Menthol 2.1g Dexamethasone acetate 0.5g

[0046] Fluocinolone acetate 0.2g Glycerin 65g Stearic acid 120g Triethanolamine 10g

[0047] Liquid paraffin 190g Paraffin 80g Ethylparaben 13g Purified water 420g

[0048] Preparation:

[0049] Extract the effective medicinal ingredients of rhubarb, turmeric, scutellaria baicalensis, and licorice in the prescription that meet the requirements of the Pharmacopoeia with water, and crush the sulfur into a 75-90um ultra-fine powder with borneol, menthol, dexamethasone acetate, and fluocinolone acetate according to the weight ratio Grind evenly and then mix with the extracts of the above-mentioned four effective medicinal ingredients. The excipients glycerin, stearic acid, triethanolamine, liquid paraffin, paraffin, ethylparaben and purified water are heated and melted in a container, stirred evenly and condens...

Embodiment 3

[0051] composition:

[0052] Rhubarb 92g Turmeric 70g Sulfur 55g Scutellaria baicalensis 10g

[0053] licorice 10g borneol 7g menthol 5g dexamethasone acetate 0.4g

[0054] Fluocinolone acetate 0.6g Polyacrylic acid 50g Triethanolamine 4g Propylene glycol 300g

[0055] EDTA disodium 2g benzoic acid 2g purified water 540g

[0056] Preparation:

[0057] Extract the effective medicinal ingredients of rhubarb, turmeric, scutellaria baicalensis, and licorice in the prescription that meet the requirements of the Pharmacopoeia with water, and crush the sulfur into a 75-90um ultra-fine powder with borneol, menthol, dexamethasone acetate, and fluocinolone acetate according to the weight ratio Grind evenly and then mix with the extracts of the above-mentioned four effective medicinal ingredients. The auxiliary material components polyacrylic acid, triethanolamine, disodium edetate, propylene glycol, benzoic acid and purified water are heated and melted in a container, stirred evenly...

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Abstract

The invention relates to an external preparation on the skin, which has obvious effects of inflammation reduction, itching relief and sanitization; active The components contain: rhubarb, turmeric root tuber, sublimed sulfur, baical skullcap root, radix glycyrrhizae, borneol, menthol and adrenal cortex hormone; calculated as pharmacological raw materials, the weight proportion of the active components rhubarb, turmeric root tuber, sublimed sulfur, baical skullcap root, radix glycyrrhizae, borneol and menthol are: 1 to 99 portion of rhubarb, 1 to 80 portion of turmeric root tuber, 1 to 70 portion of sublimed sulfur, 1 to 20 portion of baical skullcap root, 0.1 to 18 portion of radix glycyrrhizae, 0.1 to 10 portion of borneol, 0.1 to 10 portion of menthol and 0.1 to 10 portion adrenal cortex hormone. After smeared on the illness, the preparation has strong and quick disinfectant effect, can clean and care the skin, with good safety, little adverse reaction and low recurrence rate. In particular, when the skin is injured and a chronic disease is led, the preparation can still be used repeatedly for a long time, with obvious effect, convenience in us, and without side effect of hormones medicine.

Description

technical field [0001] The invention relates to an external skin preparation, which has remarkable anti-inflammatory, antipruritic, disinfection and sterilization effects, and can be used in different forms or purposes such as a therapeutic drug and / or a disinfectant for auxiliary treatment, a sanitary product, and the like. Background technique [0002] Neurodermatitis, eczema, tinea pedis, psoriasis and other common and frequently-occurring diseases with pruritus as the main symptom. The external preparations such as ointment, emulsifiable paste and antiseptic preparation that the medicine of above-mentioned disease is made more, are based on antipruritic. [0003] External use of adrenocortical hormone can be used to treat neurodermatitis, contact dermatitis, seborrheic dermatitis and chronic eczema, etc., but the use of this type of hormone drugs has many side effects. Neither external use nor oral administration can eliminate the damage to the body's adrenal cortex fun...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P17/00A61P17/04A61P31/02A61K31/045A61K31/573A61K33/04
Inventor 王建生
Owner 西藏海容唐果药业有限公司
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