Method for preparing natural alpha-linolenic acid from crude oil of idesia polycarpa var.vestita diels

Abstract

The invention discloses a method for preparing natural alpha-linolenic acid from crude oil of idesia polycarpa var.vestita diels and belongs to the fields of medicines, food and feed. The technology mainly comprises the technical processes of preparing mixed fatty acid, preparing fatty acid ethyl ester, performing urea clathration, performing silica gel column chromatography, drying under reduced pressure and the like. The method is characterized in that: enrichment is performed by a urea clathration method, so the improvement on alpha-linolenic acid content is facilitated, impurities are removed, loss is reduced, yield is increased and the burden of the subsequent operation is reduced; the clathration technical process is optimized by substituting ethanol for methanol, so toxic reagents such as methanol and the like are not used; purification is performed by a silica gel column chromatographic technology, so purity and quality of products are improved; the technical process is simple, convenient and economic, and is high in operability; the requirement on equipment is not high; most of the used reagents can be recycled, so cost is obviously reduced and the method is economic and environment-friendly; and the method is suitable for production of enterprises with different scales and has wide application prospect in the production of high-quality alpha-linolenic acid.

Description

technical field [0001] The invention belongs to the fields of medicine, food and feed, and particularly relates to a method for producing natural α-linolenic acid by using jatropha tomentosa crude oil as a raw material. Background technique [0002] Jatropha Maoye is a unique woody oil plant species in my country. It has the characteristics of wide distribution, low requirements on soil and climate, and strong adaptability. It is suitable for planting in low-quality, barren slopes, tidal flats, and mountains. , easy to promote, and easy to popularize". It is an economic crop with high yield and high economic value, and has great application value and development potential. According to data reports: Jatropha jatropha has a fruit-producing period as long as 70-100 years, and its fruit oil content is relatively high (oil production per plant can reach 200-300kg), especially its oily unsaturated fatty acid is as high as 82% or more, and it is rich in oil. Contains linoleic aci...

AI Technical Summary

Problems solved by technology

[0005] At present, the methods for preparing natural α-linolenic acid in industry mainly include: urea inclusion method, which has relatively mature technology, relatively simple equipment, uncomplicated operation, and is easy to promote and apply, but it cannot combine different carbon chain lengths with the same degree of saturation. Or similar fatty acids are separated, and the purity of the target product is low; silica gel column chromatography, the purity of the target product is high, and it is an effective method for purifying polyunsaturated fatty acids; molecular distillation, its high efficiency, low distillation temperature, The heating time is short and can effectively prevent the oxidative decomposition of polyunsaturated fatty acids, but it is difficult to separate fatty acids with carbon numbers and boiling points equivalent or similar to α-linolenic acid, the final purity of the product is low (about 70%), and the equipment is expensive ; silver ion complexation method, the separation effect of this method is good and the product purity is very high, but the output is small, the cost is high, and some eluents are easy to contaminate the product; the low temperature crystallization method is simple and easy to implement, but the separation effect is not good. Good; lipase method has mild catalytic conditions and stable product quality, but the reaction environment is complicated and the reaction direction is difficult to control, so it can only increase a certain concentration relatively; in addition, there is supercritical flow CO 2 Extraction, etc.