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Medical moist composite dressing and preparation method thereof

A manufacturing method, wet technology, applied in medical science, non-woven fabrics, textiles and papermaking, etc., can solve the problems of frequent replacement of medical wet dressings, achieve the effect of facilitating the growth of crawling, reducing the number of replacements, and accelerating healing

Inactive Publication Date: 2012-02-15
CHINESE TEXTILE ACAD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims to provide a medical wet composite dressing and its manufacturing method to solve the technical problem of frequent replacement of traditional Chinese medical wet dressings in use

Method used

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  • Medical moist composite dressing and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] First, the polyglycol lactide slices are dried under vacuum (vacuum degree 750-760mmHg) for 12 hours at a drying temperature of 120°C, and the moisture content of the slices after drying is less than 80 ppm. The dried polyglycolide chips are extruded by a screw on a spinning and drafting integrated machine, drafted in two stages, and wound to obtain polyglycolide filaments. The screw temperature is respectively: Zone 1 220 ℃, Zone 2 230℃, zone 3 230℃, zone 4 240℃; spinning melt pump (0.3cc) speed is 16r / min; the temperature and speed of the first drafting roll are 50℃, 120m / min; second drafting The temperature and speed of the roller are respectively 70°C and 380m / min; the temperature and speed of the third drafting roller are 120°C and 600m / min respectively; the winding speed is 580m / min. The obtained fiber had a breaking strength of 5.8 cN / dtex, a breaking elongation of 22.0%, and a strength retention rate of 30 to 50% in 2 weeks. After the obtained polyglycolide fila...

Embodiment 2

[0032] According to the same method as described in Example 1, a polyglycolide staple fiber with a monofilament fineness of 2.5dtex and a length of 55mm was obtained. The polyglycolide staple fiber and the sodium carboxymethyl cellulose staple fiber (monofilament fineness 1.5dtex, fiber length 51mm, breaking strength 1.5~3.5cN / dtex) pre-mixed according to the weight ratio of 30:70, and then go through opening, mixing, carding, laying, pre-needling, lower main needle, upper main needle, heat treatment (110℃), forming and processing into needle punched non-woven fabric. For the acupuncture process, select 40# puncture needle, puncture 3 times, the depth of acupuncture is 6mm, 3~4mm, 3~4mm respectively. Among them, the density of the medical composite dressing is controlled to 160g / m by adjusting the thickness of the mesh 2 , The water absorption rate reaches more than 10 times, and the bidirectional breaking elongation rate> 30%. Adjust the pH of the medical composite dressing t...

Embodiment 3

[0034] According to the same method as described in Example 1, a polyglycolide staple fiber with a monofilament fineness of 3.5dtex and a length of 76mm was obtained. The polyglycolide staple fiber and the sodium carboxymethyl cellulose staple fiber (monofilament fineness 1.5dtex, fiber length 45mm, breaking strength 1.5~3.5cN / dtex) pre-mixed according to the weight ratio of 40:60, and then go through opening, mixing, carding, laying, pre-needling, lower main needle, upper main needle, heat treatment (140℃), formed, processed into needle punched non-woven fabric, and then sterilized by gamma rays. For the acupuncture process, select 40# puncture needle, puncture 3 times, the depth of acupuncture is 6mm, 3~4mm, 3~4mm respectively. Among them, the density of the medical composite dressing is controlled to 130g / m by adjusting the thickness of the mesh 2 , The water absorption rate reaches more than 10 times, and the bidirectional breaking elongation rate> 30%. Adjust the pH of th...

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Abstract

The invention discloses a medical moist composite dressing which comprises 20-50% of poly(glycolide-co-lactide) (PGLA) and 50-80% of sodium carboxymethylcellulose by mass percent. According to the technical scheme disclosed by the invention, as the medical moist composite dressing comprises the PGLA and the sodium carboxymethylcellulose and the PGLA has good mechanical properties, a network structure is formed in the dressing, thus forming protective layers on the surfaces of wounds, avoiding secondary wounds, providing space and nutrition exchange environment for granulation growth in the wound healing process or facilitating epithelium climbing growth, and being beneficial to wound healing; used as the dressing, the sodium carboxymethylcellulose can absorb plenty of exuded tissue fluid and prevent formation of adhesion during regeneration of the epithelium and movement of inflammatory cells and other cells while keeping the wounds moist; and through the synergy of the PGLA and the sodium carboxymethylcellulose, the change times of the dressing can be reduced, and wound healing can be accelerated.

Description

Technical field [0001] The present invention relates to the field of medical consumables and their manufacturing, in particular to a medical wet composite dressing and a manufacturing method thereof. Background technique [0002] Textile wound dressings are one of the most important medical consumables in modern medicine. Traditional dressings mainly include gauze, sponges, bandages and other dry dressings that can expose the wound to oxygen. In 1962, Dr. Winter of the University of London proved that wounds using moist dressings heal more naturally than those exposed to the air, and the healing speed of wounds is significantly faster. A large number of basic and clinical studies subsequently support this view. In the 1990s, high-end wet dressings using biological materials, polymer materials, composite materials, etc. as raw materials developed rapidly. In August 2000, the U.S. Food and Drug Administration (FDA) specifically emphasized in the new industry guidelines for wound m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/26D04H1/42D04H1/46
Inventor 黄庆徐纪刚周杰曲希明崔华帅吴鹏飞史贤宁李杰沈锂鸣
Owner CHINESE TEXTILE ACAD
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