Protamine compounded preparation, preparation method and application thereof
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A protamine and preparation technology, applied to the application of the protamine compound preparation, the field of preparing the protamine compound preparation, can solve the problems of low efficiency, high cost, large toxic and side effects on human body and the like
Active Publication Date: 2012-04-11
广东康乃欣生物医疗科技有限公司
View PDF1 Cites 5 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
[0006] 3. It is not easy to degrade, has corrosion, and the discharge will pollute the environment
[0007] 4. High cost, low efficiency, and time-consuming
The indiscriminate use of antibiotics not only makes the strains resistant, but also has great toxic and side effects on the human body.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0153] Protamine compound preparation of the present invention is made up of the content of following percentage by weight:
[0154] Proportion:
[0155]
[0156] Method: In a sterile room or ultra-clean workbench, accurately weigh the above reagents, protamine 0.3g, water-soluble chitosan 1.9g, glycine 1.1g, monoglyceride 0.5g, sodium acetate 0.1g, acetic acid 0.1g, 96ml (96g) of sterilized distilled water, put it into a clean glass or stainless steel container, stir gently, mix well, and then pack it into a sterile container.
[0157] Application: This formula can be used to make skin and mucous membrane bactericidal disinfectant, which can kill Staphylococcus aureus, Candida albicans, and Escherichia coli on the surface of skin and mucous membranes within 2-10 minutes, with a killing rate of 99.8%. It can treat abscesses, psoriasis, ulcers, bedsores, scalds, burns, boils, oral ulcers, cuts, vaginitis, oral diseases caused by various bacterial infections, and prevent sex...
Embodiment 2
[0159] Protamine compound preparation of the present invention is made up of the content of following percentage by weight:
[0160] Proportion:
[0161]
[0162] Method: Put 10g of acetic acid into a clean glass or stainless steel container in a sterile room or ultra-clean workbench, add 67ml of sterilized distilled water, stir gently, mix well, and then add 10g of water-soluble chitosan After homogenization, add 0.01g of protamine, 10g of glycine, 0.1g of monoglyceride, and 2.89g of sodium acetate, mix thoroughly and evenly, and pack it into a sterile container.
Embodiment 3
[0164] Protamine compound preparation of the present invention is made up of the content of following percentage by weight:
[0165] Proportion:
[0166]
[0167] Method: Mix it evenly in the same way as 1 and 2 above, put it into a sterile liquid-carrying container and seal it.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Property
Measurement
Unit
degree of carboxylation
aaaaa
aaaaa
Login to view more
Abstract
The invention discloses protamine compounded preparation, a preparation method and application thereof. The protamine compounded preparation of the invention can be singly prepared with the protamine and chitosan, or prepared by compounding one or mixture of over two of glycine, sodium acetate, undecynol monoglyceride, acetic acid, absolute alcohol, lysostaphin, lysozyme, anti-bacterial peptide and sterilized distilled water. The method for preparing the protamine compounded preparation comprises the following steps: accurately weighting each component according to rate in aseptic or clean workshops; putting in clean glass or stainless steel, and uniformly stirring; and sealing in sterile containers. The product not only effectively kills the gram-positive cocci, such as staphyloccocus aureus rosenbach, monilia albican, neisseria gonorrhoeae, streptococcus, anaerobic bacteria, pseudomonas aeruginosa, escherichia coli, pneumococcus, D enterococcus, staphylococcus tetragenus, listeria monocytogenes, stenotrophomonas maltophilia and stomach helicobacter pylori, but also kills the gram-negative bacteria.
Description
technical field [0001] The invention relates to a protamine compound preparation, a method for preparing the protamine compound preparation, and an application of the protamine compound preparation. Background technique [0002] Most of the traditional disinfectants currently on the market contain chemical reagents such as chlorine, alcohols, classics, aldehydes, and phenols. Such as phenols, acids, and alcohols that coagulate proteins to denature them for disinfection; sodium hydroxide, lime, etc. that dissolve proteins; strong oxidation bleaching powder, peracetic acid, etc.; formalin and protein amino binding, glutaraldehyde and microorganisms Protein reaction and other disinfection reagents. [0003] There are one or more of the following shortcomings in the vast majority of the above disinfection reagents: [0004] 1. There are residues and toxic side effects for disinfection patients. [0005] 2. Strong irritation to skin mucous membranes, wounds and wounds. [000...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more