Asymmetrical polyurethane/nano TiO2 thin film wound dressing and preparation method thereof

A wound dressing and polyurethane technology, applied in the field of medical wound dressing and its preparation, can solve the problems of physiological toxicity, inability to fully meet the use requirements of medical wound dressing, secondary injury of newborn tissue, etc., and achieve the effect of accelerating the healing rate
CN102430145AInactive Publication Date: 2012-05-02SICHUAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SICHUAN UNIV
Publication Date
2012-05-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an asymmetrical polyurethane / nano TiO2 thin film wound dressing, which is characterized by being composed of a dense surface layer and a porous support layer, wherein the dense surface layer is integrally shaped with the porous support layer, the dense surface layer has the thickness of 7-15 mu m, the porous support layer has the total pore volume of 4.80-5.24 cm<3> / g, and in-situ generated nano TiO2 particles are uniformly dispersed in an entire polyurethane thin film and have the particle size of 30-150 nm. The invention also discloses a preparation method of the asymmetrical polyurethane / nano TiO2 thin film wound dressing. In the technical scheme disclosed by the invention, a solvent evaporation film-forming method, a wet process phase inversion film-forming method and a nano particle in-situ generation technique are felicitously organically combined, the structure of the polyurethane thin film wound dressing is reconstructed, the defects of the existing performance of the polyurethane thin film wound dressing are compensated, the comprehensive and clinical application value of the product is greatly improved, and a new method is provided for preparation of the asymmetrical polyurethane / nano TiO2 thin film wound dressing.
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Description

technical field

[0001] The invention belongs to the technical field of medical wound dressing and its preparation, in particular to an asymmetric polyurethane / nano-TiO 2 Film wound dressing and method for its preparation. Background technique

[0002] In the clinical treatment of burns, wounds in skin grafting areas / donor areas, surgical wounds, and various types of ulcers, bedsores, pressure sores, sinus tracts and other refractory chronic wounds, the use of wound dressings can play a role in the rapid healing of wounds. to a great boost. Modern medicine believes that an ideal medical wound dressing should at least have the following functional characteristics: (1) Moderate moisture permeability (2000-2500g / m 2. 24h), to control the evaporation rate of tissue fluid secreted by the wound, to ensure that there is neither accumulation of excess tissue fluid nor complete dehydration and scab on the wound (moist healing theory); Oxygen / carbon dioxide exchange, promoting cell ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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