Unlock instant, AI-driven research and patent intelligence for your innovation.

Animal codonopsis pilosula polysaccharide oral solution and preparation method thereof

A technology of Codonopsis polysaccharides and oral liquid, which is applied in the field of modern Chinese veterinary drug compound preparations, can solve problems such as increased production costs, inability to efficiently extract polysaccharide components, and product efficacy discounts

Active Publication Date: 2013-10-30
JIANGXI NEW CENTURY MINXING ANIMAL HEALTH PROD CO LTD
View PDF6 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, in the existing technology, the traditional water extraction and alcohol precipitation method cannot efficiently extract polysaccharide components, and the product is mixed with a large amount of impurities, so multiple extractions are required, which not only affects production efficiency, increases production costs, but also affects product efficacy. Big discount

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Animal codonopsis pilosula polysaccharide oral solution and preparation method thereof
  • Animal codonopsis pilosula polysaccharide oral solution and preparation method thereof
  • Animal codonopsis pilosula polysaccharide oral solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A Codonopsis polysaccharide oral liquid is composed of the following raw material ratios: Codonopsis 2000g and sodium benzoate 3g.

[0025] The above-mentioned Codonopsis polysaccharide oral liquid is prepared by the following steps:

[0026] 1. Pretreatment: Accurately weigh 2000g of Codonopsis pilosula, cut and pulverize;

[0027] 2. Petroleum ether degreasing: extract the processed Codonopsis pilosula at 80°C with 6 times the weight of the medicinal material in petroleum ether for 1 hour, filter, and take the filter residue;

[0028] 3. Ethanol reflux decolorization and impurity removal: extract the filter residue with ethanol 10 times the weight of the filter residue for 1 hour, and obtain the medicinal residue after filtration;

[0029] 4. Water extraction: Add 8 times the weight of the dregs to decoct in water for 2 times, the first time for 2 hours, the second time for 1.5 hours, combine the decoction, and filter;

[0030] 5. Removal of starch: add 24g of amyla...

Embodiment 2

[0037] A Codonopsis polysaccharide oral liquid is composed of the following raw material ratios: Codonopsis 2200g and sodium benzoate 3g.

[0038] The above-mentioned Codonopsis polysaccharide oral liquid is prepared by the following steps:

[0039] 1. Pretreatment: Accurately weigh 2200g of Codonopsis pilosula, cut and pulverize;

[0040] 2. Petroleum ether degreasing: extract the processed Codonopsis pilosula at 85°C with 8 times the weight of the medicinal material in petroleum ether for 1.5 hours, filter, and take the filter residue;

[0041] 3. Ethanol reflux decolorization and impurity removal: extract the filter residue with ethanol 10 times the weight of the filter residue for 2 hours, and obtain the medicinal residue after filtration;

[0042] 4. Water extraction: add 8 times the weight of the dregs to the decoction twice, the first time for 3 hours, the second time for 1.5 hours, combine the decoction, and filter;

[0043] 5. Removing starch: add 28g of amylase in ...

Embodiment 3

[0050] A Codonopsis polysaccharide oral liquid is composed of the following raw material ratios: Codonopsis 1800g and sodium benzoate 3g.

[0051] The above-mentioned Codonopsis polysaccharide oral liquid is prepared by the following steps:

[0052] 1. Pretreatment: Accurately weigh 1800g of Codonopsis pilosula, cut and pulverize;

[0053] 2. Water extraction: Add 10 times the weight of medicinal materials and decoct twice, the first time for 3 hours, the second time for 2 hours, combine the decoction, and filter;

[0054] 3. Removal of starch: add 20g of amylase in a water bath for enzymolysis for 1 hour, after the reaction, boil water to inactivate the enzyme for 5 minutes, cool to room temperature, centrifuge at 3000r / min for 5 minutes, and take the supernatant;

[0055] 4. Concentration: the supernatant is concentrated to 2 / 3 (V / W) of the crude drug amount;

[0056] 5. Alcohol precipitation: Add 95% ethanol to the concentrated solution to make the alcohol content reach 8...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to animal codonopsis pilosula polysaccharide oral solution. A preparation method of the animal codonopsis pilosula polysaccharide oral solution comprises the steps of smashing codonopsis pilosula, degreasing and decolorizing, adding 8 times to 12 times of water, extracting for 1 hour to 3 hours 1 time to 3 times, performing enzymolysis with amylase, concentrating ethanol precipitation, adding papain of 18 kilograms to 48 kilograms for two hours, adding a Sevag agent with the volume of 18% to 30% volume of filter liquid to fully oscillate, centrifuging to obtain supernate, concentrating the supernate to 2 / 3 of crude drug and finally diluting, distributing and packing. The animal codonopsis pilosula polysaccharide oral solution is a novel drug form of traditional Chinese veterinary medicine with codonopsis pilosula polysaccharide as a raw material, uses reasonable and convenient extraction refining process to effectively remove impurities, greatly improves content of active ingredient, is not prone to sedimentation, is favorable of industrial batch production, has the advantages of being small in using dosage, high in biological utilization degree and convenient to take, and can enhance organism immunity, anti-cancer effect, anti-oxidation effect, anti-stress effect, antibiosis and antiviral effect of livestock.

Description

technical field [0001] The invention relates to a compound preparation of modern Chinese veterinary medicine, in particular to Codonopsis polysaccharide oral liquid. Background technique [0002] Codonopsis Codonopsis is the dried root of Codonopsis Codonopsis, Suhua Codonopsis or Sichuan Codonopsis. It is mainly distributed in Northeast China, North China and Shaanxi, Ningxia, Gansu, Qinghai, Henan, Sichuan, Yunnan, Tibet and other places. The resources are relatively rich, and its practical value is fully tapped, which has good social and economic benefits. In animal health products, it can be used for livestock and poultry with weak spleen and stomach, less food for diarrhea, cough and asthma due to lung deficiency, fatigue and weakness, and prolapse of qi deficiency. [0003] The main components of Codonopsis pilosula are polysaccharides, codonopsis, sterols, triterpenoids, alkaloids, lactones, and beans. Codonopsis polysaccharides are composed of important monosacchar...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K31/715A61P3/08A61P7/06A61P9/12A61P39/00A61P37/04A61P1/04A61K36/344
Inventor 晏永新
Owner JIANGXI NEW CENTURY MINXING ANIMAL HEALTH PROD CO LTD