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Medicine composition for treating infectious bursal diseases of chickens and preparation method thereof

A technology for bursitis and chicken infectivity is applied in the field of veterinary medicine to achieve the effect of reasonable composition, low cost and high bioavailability

Inactive Publication Date: 2012-12-26
ZHENGZHOU HOUYI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although anti-IBDV hyperimmune serum and hyperimmune yolk antibody can be used for treatment, both have hidden dangers of spreading other infectious pathogens. The Ministry of Agriculture has banned the production and clinical use of hyperimmune serum and yolk antibody in 2004

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A kind of pharmaceutical composition for the treatment of chicken infectious bursitis of the present embodiment is formulated according to the following traditional Chinese medicine composition in parts by weight: 40 parts of Dandelion, 60 parts of Folium Isatidis, 160 parts of Radix Isatidis, 40 parts of Honeysuckle, and 20 parts of Scutellaria baicalensis , 20 parts of Cortex Phellodendri, 20 parts of Huoxiang, 60 parts of Gypsum, 40 parts of Licorice, 25 parts of Citric Acid, 5 parts of Sodium Saccharin, 40 parts of Sodium Bicarbonate, 60003 parts of Polyethylene Glycol.

[0028] The specific operation steps of the preparation method are as follows:

[0029] (1) Take dandelion, Folium Isatidis, Radix Isatidis, honeysuckle, scutellaria baicalensis, Phellodendron phellodendron, Huoxiang, gypsum, and licorice according to the above parts by weight, crush and mix evenly;

[0030] (2) Decocting and extracting with distilled water, extracting twice, 2 hours each time;

[...

Embodiment 2

[0036] A kind of pharmaceutical composition for the treatment of chicken infectious bursitis of the present embodiment is prepared according to the following traditional Chinese medicine composition by weight: 60 parts of Dandelion, 80 parts of Folium Isatidis, 200 parts of Radix Isatidis, 60 parts of Honeysuckle, and 40 parts of Scutellaria baicalensis , 40 parts of cortex, 40 parts of Huoxiang, 80 parts of gypsum, 60 parts of licorice, 30 parts of tartaric acid, 8 parts of sucrose, 50 parts of potassium bicarbonate, and 40005 parts of polyethylene glycol.

[0037] The specific operation steps are as follows:

[0038] (1) Take dandelion, Folium Isatidis, Radix Isatidis, honeysuckle, scutellaria baicalensis, Phellodendron phellodendron, Huoxiang, gypsum, and licorice according to the above parts by weight, crush and mix evenly;

[0039] (2) Decocting and extracting with distilled water, extracting 3 times, 2 hours each time;

[0040] (3) Filtrate, combine the extracts, precip...

Embodiment 3

[0045] A kind of pharmaceutical composition for the treatment of chicken infectious bursitis of the present embodiment is formulated according to the following traditional Chinese medicine composition in parts by weight: 80 parts of Dandelion, 100 parts of Folium Isatidis, 240 parts of Radix Isatidis, 80 parts of Honeysuckle, and 60 parts of Scutellaria baicalensis , 60 parts of cortex, 60 parts of Huoxiang, 120 parts of gypsum, 80 parts of licorice, 15 parts of citric acid, 5 parts of fumaric acid, 20 parts of malic acid, 15 parts of sodium saccharin, 5 parts of glycyrrhizin, 20 parts of sorbitol , 20 parts of sodium bicarbonate, 20 parts of sodium carbonate, 20 parts of potassium carbonate, 60002 parts of polyethylene glycol, 20 parts of polyethylene glycol, 2 parts of magnesium stearate.

[0046] The specific operation steps are as follows:

[0047] (1) Take dandelion, Folium Isatidis, Radix Isatidis, honeysuckle, scutellaria baicalensis, Phellodendron phellodendron, Huoxia...

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Abstract

The invention discloses a medicine composition for treating the infectious bursal diseases of chickens and a preparation method thereof. The medicine composition for treating the infectious bursal diseases of the chickens is prepared by the following traditional Chinese medicines according to a certain proportion in parts by weight: 40 to 80 parts of dandelion, 60 to 100 parts of isatis leaf, 160 to 240 parts of radix isatidis, 40 to 80 parts of honeysuckle, 20 to 60 parts of baikal skullcap root, 20 to 60 parts of yellow-corktree bark, 20 to 60 parts of wrinkled giant hyssop, 60 to 120 parts of gypsum, 40 to 80 parts of licorice, 25 to 40 parts of organic acid, 40 to 60 parts of weak base, 3 to 6 parts of lubricant and 5 to 10 parts of sweetening agent. The preparation formulation of the composition is effervescent granules. The preparation method comprises the following steps of: pulverizing the bulk drugs, adding water, decocting, carrying out alcohol precipitation on filtrate, concentrating after recovering ethanol from supernatant liquid, and drying so as to obtain an extract; and dividing the extract into two equal parts, adding the organic acid, the lubricant and the sweetening agent into one part so as to prepare acid granules, drying for standby application, adding the weak base, the lubricant and the sweetening agent into the other part so as to prepare alkali granules, drying for standby application, then mixing the two kinds of granules evenly, granulating and packaging so as to obtain the medicine composition for treating the infectious bursal diseases of the chickens. Various medicines in the medicine composition for treating the infectious bursal diseases of the chickens are combined for use. The medicine composition for treating the infectious bursal diseases of the chickens has the effects of invigorating qi, strengthening the spleen, nourishing yin, clearing heat, cooling blood, removing toxic materials and the like. The effect of treating the infectious bursal diseases of the chickens by utilizing the medicine composition for treating the infectious bursal diseases of the chickens is obvious; and moreover, the cost is low, and the toxic or side effect is small.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating chicken infectious bursitis and a preparation method thereof, belonging to the field of veterinary medicine. Background technique [0002] Infectious bursal disease (IBD) is an acute, highly contagious disease of 2-6 week-old chicks caused by infectious bursal virus. It is characterized by swelling, hemorrhage, and necrosis of the bursa of Fabricius, hemorrhage of pectoralis and leg muscles, and strip hemorrhage at the junction of glandular stomach and gizzard. The clinical manifestations were lack of energy, anorexia, indirect diarrhea, tremor and severe weakness. The autopsy changes were characterized by dehydration, skeletal muscle hemorrhage, renal tubular urate deposition, enlarged cyst of Fabricius and hemorrhage. The harm of this disease is mainly that the virus invades the humoral immune center of chickens - the bursa of Fabricius, which destroys the production of lymphocytes i...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K36/855A61P31/14A61K33/06
Inventor 吴红云王丽景李建正
Owner ZHENGZHOU HOUYI PHARMA
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