Lactobacillus casei and culture medium thereof

Abstract

The invention discloses a lactobacillus casei and a culture medium thereof. The bacterial strain is stored in China General Microbiological Culture Collection Center with the registration number of CGMCC NO. 3993; the Latin name of the strain is Lactobacillus casei L7-13; and the bacterial strain has the morphological characteristics of gram positive bacteria, no spore grown, no flagella, no motion, rough bacterial colony, offwhite or light yellow. The invention also discloses the complete sequence of 16s ribosome DNA (16S rDNA) of the bacteria; the lactobacillus casei is high in lactic acid generation speed and high in acid productivity, and further high in reproduction speed, high in activity and good in stress resistance; besides, the lactobacillus casei has the function of improving the gastrointestinal tract and thereby is capable of inhibiting colonization of harmful bacteria; the lactobacillus casei is capable of generating bile salt hydrolase and decomposing bound cholic acid into free cholic acid; and, the free cholic acid and cholesterol can form a composite so as to settle down together; therefore, the lactobacillus casei is capable of reducing cholesterol.

Description

technical field [0001] The invention provides a kind of lactobacillus casei (Lactobacillus casei L7-13) and culture medium thereof. Background technique [0002] Lactobacillus casei (Lactobacillus casei L7-13) belongs to the genus Lactobacillus, is a gram-positive bacterium that does not produce spores, has no flagella, and does not move; it is facultatively anaerobic, sometimes slightly aerobic, and grows in the presence of oxygen Poor, grows better when oxygen partial pressure is lowered; facultative heterofermentation of lactose, no liquefaction of gelatin, no reduction of nitrate, negative for catalase and oxidase; optimum growth temperature is 37°C, G+C content is 45.6% ~47.2%; the length of the bacteria is different, the two ends are square, and often form a chain; the colony is rough, off-white, sometimes slightly yellow, and can ferment various sugars. Lactobacillus casei is widely distributed and usually exists in human mouth, intestinal contents, stool and vagina....

AI Technical Summary

Problems solved by technology

[0007] (4) Cholesterol-lowering effect Cholesterol plays an important physiological role in the human body, but high serum cholesterol levels can easily induce arteriosclerosis, leading to a series of cardiovascular diseases

Existing vaccines and antibiotics often only treat diseases caused by certain known pathogenic microorganisms, but are powerless against their variants

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