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Traditional Chinese medicine composition for treating porcine transmissible gastroenteritis

A composition and infectious technology, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of antibiotic resistance residue, treating the symptoms but not the root cause, and improper inoculation route, and achieves less toxic and side effects, good curative effect, and price. low cost effect

Inactive Publication Date: 2013-07-24
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For porcine transmissible gastroenteritis, immunotherapy is mainly used at present. Although it has the advantages of strong immunity and long immune protection period, some attenuated vaccines still have residual virulence, and individual attenuated live vaccines will still cause immunity in inoculated animals. Inhibition, the potential harm of attenuated vaccine reversion to ancestors still exists. On the other hand, due to improper immunization schedule or inappropriate vaccination route, immunization failure can also be caused
Although the application of symptomatic therapy can produce a certain curative effect, it only treats the symptoms but not the root cause, which often leads to recurrent attacks of the disease
In addition, the use of antibiotics is prone to drug resistance and residue problems, which is not conducive to the diagnosis and treatment of diseases, and hinders the export of animal food in my country
At present, veterinary clinics still lack safe and effective drugs for the prevention and treatment of porcine transmissible gastroenteritis, so it is imminent to develop drugs for the prevention and treatment of this disease

Method used

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preparation example Construction

[0025] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine composition. When the traditional Chinese medicine composition is a decoction liquid, the specific steps are: mix the raw materials in parts by weight, add 5 to 7 times of water relative to the mixture, and heat with high fire Bring to boiling state, then decoct with slow fire for 2-4 hours, filter the decoction, add 3-5 times water to the filter residue again, heat to boiling state with strong fire, then decoct with slow fire for 2-4 hours, decoct The decoction is filtered, the filtrates obtained twice are combined, concentrated to remove part of the water, and the decoction of the traditional Chinese medicine composition with a crude drug concentration of 1 g / ml-2 g / ml is obtained.

[0026] The invention also provides a method for using the decoction liquid. Each piglet within 30 days old is fed with 10ml-20ml each time, and piglets over 30 days old are fed with...

Embodiment 1

[0054] Example 1 Decoction 1

[0055]Take 25g of Muxiang, 65g of Qingdai, 35g of Solidago, 30g of Bangui, 35g of Asparagus, 25g of Fresh Bamboo Lek, 20g of Pteroptera, 25g of Coix Seed, 15g of Weasel, 25g of Tengzi, 30g of Toon Bark, and Mix 35g of herb, 25g of Osmanthus chinensis, 30g of kudzu root, 25g of jiubing, 40g of dodder, 55g of sealwort, 25g of yellow hollyhock, 45g of Phellodendron phellodendri, 20g of mulberry, 25g of boxing ginseng, 65g of codonopsis and 25g of qinpi, add 4.5kg of water , heated to a boiling state with a strong fire, then decocted with a slow fire for 4 hours, filtered the decoction, added 3kg of water to the filter residue, heated to a boiling state with a strong fire, and then decocted with a slow fire for 3 hours, filtered the decoction, and the two The filtrates obtained for the second time were combined, concentrated to remove part of the water, and the decoction 1 of the Chinese medicine composition with a crude drug concentration of 1 g / ml ...

Embodiment 2

[0056] Embodiment 2 Decoction 2

[0057] Take 20g Muxiang, 60g Qingdai, 30g Solidago, 25g Barbangui, 30g Asparagus, 20g Fresh Bamboo Lek, 15g Pteroptera, 20g Coix Seed, 20g Scutellaria chinensis, 30g Tengzi, 35g Chunpi, Goose Bud Herb-eating 40g, Osmanthus chinensis 30g, kudzu root 30~35g by weight, jiubing 30g, dodder 45g, sealwort 60g, hollyhock flower 30g, Phellodendron 50g, mulberry 25g, fist ginseng 30g, codonopsis 70g and Qinpi 30g mixed, Add 4.5kg of water, heat to boiling state with strong fire, then decoct with slow fire for 4 hours, filter the decoction, add 3kg of water to the filter residue, heat to boiling state with strong fire, then decoct with slow fire for 3 hours, decoction Filtrate, combine the filtrates obtained twice, concentrate to remove part of the water, and obtain the Chinese medicine composition decoction 2 with a crude drug concentration of 2 g / ml.

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Abstract

The invention provides a traditional Chinese medicine composition for treating porcine transmissible gastroenteritis. The traditional Chinese medicine composition comprises the following active pharmaceutical ingredients: costustoot, natural indigo, common goldenrod, perfoliote knotweed herb, cochinchnese asparagus root, fresh bamboo sap, pterocephalus hookeri, coix seed, common St. Paulswort herb, entada phaseoloides, tree-of-heaven ailanthus bark, small centipeda herb, Japanese flowering fern rhizome, kudzuvine root, ovateleaf holly bark, south dodder seed, rhizome, abelmoschus manihot, amur corktree bark, Chinese taxillus twig, bistort rhizome, pilose Asiabell root and ash bark. The traditional Chinese medicine composition can overcome the shortcomings of the existing western medicine therapy and has the advantages of good efficacy against the porcine transmissible gastroenteritis, low toxicity and side effects, less residue, rich resources and low price.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese veterinary medicine, in particular to a traditional Chinese medicine composition for treating porcine infectious gastroenteritis. Background technique [0002] Porcine transmissible gastroenteritis is an acute intestinal infectious disease caused by coronavirus. It spreads rapidly and has a high incidence. The mortality rate can reach 100% within 2 weeks of age. It mainly exists in the small intestinal mucosa and contents of pigs, and is excreted with feces and vomitus, and is transmitted through the digestive tract and respiratory tract. The disease is characterized by vomiting, diarrhea, and dehydration. , both large and small pigs can become ill, and death is rare if they are more than 2 weeks old. Doyle and Hutchings first reported the occurrence of this disease in the United States in 1945 and determined that the pathogen was a coronavirus. The disease occurred successively in J...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P1/00A61P31/14
Inventor 郝智慧侯东军吴好庭
Owner QINGDAO AGRI UNIV
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