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Method for preparing multi-layer composite functional surgical dressing

A multi-layer composite and functional technology, applied in viscous dressings, dressings, medical science, etc., can solve the problems of non-covering wound protection, repeated wound damage, limited bonding strength, etc., to prevent wound fluid infection, Good biocompatibility, the effect of avoiding direct contact

Inactive Publication Date: 2013-08-14
DONGHUA UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These sterile products are widely used in the medical industry, but there are some defects: dry gauze is easy to stick to the wound; Damaged, long-term failure to heal, or even secondary infection
[0005] In recent years, the research on chitosan biological dressings is as follows: a film-shaped or powdered chitosan dressing (patent CN100443123C) is disclosed, which contains chitosan and traditional Chinese medicine extracts or chitosan derivatives or Metal ions, the invented product has the effect of promoting wound healing and hemostasis, and at the same time can inhibit the growth of bacteria, and has good adhesion to the wound, but the membrane-shaped chitosan dressing has airtightness, poor liquid absorption, and no reverse leakage Defects in strength; powdered chitosan medical dressings have good air permeability and liquid absorption, but have no covering wound protection
A medical colloid dressing with antibacterial and healing-promoting functions (patent CN102335451A). The dressing in the invention is made of water-soluble chitin and methyl biguanide, which has the functions of analgesia, wound healing promotion and bacteriostasis. However, although this product There is a certain amount of liquid absorption, but the liquid absorption is not high
[0006] In order to make better use of the advantages of chitosan medical dressings, some multi-layer composite dressings have appeared, which further make up for the single-function defects of medical dressings on the market.
A composite chitosan dressing (patent CN201414876Y), comprising a chitosan material layer, a water-absorbing layer and a backing material layer, and the chitosan material layer is provided with air holes. Although this three-layer composite dressing has good air permeability, It has high liquid absorption performance, prevents reverse leakage, antibacterial, and promotes healing; it relates to a natural medical absorbable biological dressing (CN2400080Y), which uses chitin fiber spunlace cloth as the functional layer, and other non-woven fabric layers as buffer absorption Layer and non-woven fabric with self-adhesive effect are composed of application layer, although compared with ordinary cotton gauze and spunlace non-woven gauze, it has many outstanding advantages such as multi-function and convenient use; a multi-layer composite medical dressing (US005759570A) , the dressing includes an outer protective film, a water-absorbing layer, a molecular filtration membrane, and a wound contact layer. The layers of the composite dressing are bonded by an adhesive, which has limited performance and limited bonding strength, and requires special sizing equipment during use, which limits its use and promotion
[0007] In order to avoid the disadvantages of adhesives, a preparation method of chitin three-layer composite nonwoven fabric (CN102225638A), it is composed of chitin fiber cloth layer, viscose fiber cloth layer and ES fiber cloth layer by acupuncture process, Although it has the functions of hemostasis, antibacterial and high ability to absorb tissue exudate, the acupuncture products have poor softness and poor adhesion to the skin
[0008] To sum up, in order to overcome the single-function defects of existing medical dressings, the research and development of multilayer composite medical dressings and their production and processing technology is still a research hotspot.

Method used

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  • Method for preparing multi-layer composite functional surgical dressing
  • Method for preparing multi-layer composite functional surgical dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The preparation method of described multilayer composite functional medical dressing is as follows:

[0043] (A) Prepare functional layer 1, adopt 100% chitosan fiber, the length of chitosan is 38mm, and fineness is 1.78dtex, and 1 gram weight of the obtained functional layer is 40g / m 2 , send the fiber raw materials into the cotton storage box, lay them in piles, grab them vertically and send them to the BG038 type opening equipment for loosening, dissociation, mixing and opening until uniform, the resulting opening rate is 95%, and then through BG218 type carding Machine carding and cross-lapping machine laying nets to obtain functional layer 1 fiber web, specific process parameters: carding machine feeding speed 0.35m / min, cylinder speed 600m / min, output fiber web speed 35m / min, web laying speed 38m / min min, the output speed of the bottom curtain is 2m / min, and the unevenness of the output fiber web is 2.5%.

[0044] (B) prepare water-absorbing layer 2, adopt 100% v...

Embodiment 2

[0051] The preparation method of concrete multilayer composite functional medical dressing is as follows:

[0052] (A) prepare functional layer 1, adopt 80 / 20 chitosan fiber / viscose fiber, the length 38mm of chitosan, fineness is 1.78dtex, the length 38mm of viscose fiber, fineness is 1.68dtex, the function obtained Layer 1 gram weight is 35g / m 2 , send the fiber raw materials into the cotton storage box, lay them in piles, grab them vertically and send them to the BG038 type opening equipment for loosening, dissociation, mixing and opening until uniform, the resulting opening rate is 95%, and then through BG218 type carding The web is obtained by machine carding and cross-lapper machine, functional layer 1 web, specific process parameters: carding machine feeding speed 0.40m / min, cylinder speed 700m / min, output web speed 48m / min, web laying speed 50m / min, the output speed of the bottom curtain is 5m / min, and the unevenness of the output fiber web is 2.0%.

[0053] (B) prep...

Embodiment 3

[0060] The preparation method of concrete multilayer composite functional medical dressing is as follows:

[0061] (A) prepare functional layer 1, adopt 70 / 30 chitosan fiber / viscose fiber, the length 38mm of chitosan, fineness is 1.78dtex, the length 38mm of viscose fiber, fineness is 1.68dtex, the function obtained Layer 1 gram weight is 25g / m 2 , send the fiber raw materials into the cotton storage box, lay them in piles, grab them vertically and send them to the BG038 type opening equipment for loosening, dissociation, mixing and opening until uniform, the resulting opening rate is 95%, and then through BG218 type carding Machine carding and cross-lapping machine laying nets to obtain functional layer 1 fiber web, specific process parameters: carding machine feeding speed 0.35m / min, cylinder speed 600m / min, output fiber web speed 30m / min, web laying speed 33m / min min, the output speed of the bottom curtain is 2m / min, and the unevenness of the output fiber web is 1.8%.

[00...

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Abstract

The invention relates to a method for preparing a multi-layer composite functional surgical dressing. The method comprises the following steps: respectively and independently carding the fiber layers comprising a functional layer which is formed by mixing chitosan fiber or chitosan fiber and viscose and is directly contacted with the skin, a water-absorbing layer which is made of viscose and has high liquid absorption performance and a protective layer which is formed by mixing the viscose and polyester fiber and has the supporting and protecting functions so as to form a net, manufacturing a three-layer laminate with an upper functional layer, a middle water-absorbing layer and a lower protective layer by employing a water jet strengthening technology, coating a waterproof agent on the protective layer of the three-layer laminate to form a waterproof layer, and finally rolling to obtain the surgical dressing. The product has high biocompatibility and promotes healing, the antibacterial rate is up to 96.7 percent, the liquid absorption rate is 1259 percent, the waterproofing grade is up to level 5, and the surgical dressing can be used for clinical repair for operative incision, burn, scald, ulcer and other skin injury and is simple in production process, low in cost and environmentally-friendly.

Description

technical field [0001] The invention belongs to the field of medical dressings, in particular to a preparation method of a multilayer composite functional medical dressing. Background technique [0002] At present, for skin injuries caused by trauma, abrasions, burns, surgical incisions, diabetic ulcers, and varicose ulcers, care products mainly include degreasing gauze, petroleum jelly gauze, saline wet gauze or non-stick film. These sterile products are widely used in the medical industry, but there are some defects: dry gauze is easy to stick to the wound; Damaged, long-term failure to heal, and even secondary infection. In order to make medical dressings have antibacterial properties, scholars at home and abroad have conducted a lot of research, which are summarized as follows: [0003] A composite nano-antibacterial medical dressing (patent CN1537640A), the antibacterial layer is composed of spunlace non-woven fabric or carbon fiber adsorption material containing Ag ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F13/02A61L15/44A61L15/28
Inventor 靳向煜吴海波吴杰殷保璞王荣武王洪张初阳
Owner DONGHUA UNIV
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