Toltrazuril potassium salt soluble powder as well as preparation method and usage thereof

A toltrazuril and soluble technology, which is applied in powder delivery, pharmaceutical formulations, medical preparations of non-active ingredients, etc., can solve the unfavorable production, transportation and use of toltrazuril raw material drugs, and different mixing and administration methods. Convenience, inaccurate dosage and other problems, to achieve the effect of good solubility, small adverse reactions and significant curative effect
CN103690488AActive Publication Date: 2014-04-02HUBEI LONGXIANG PHARMA TECH CO LTD
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
HUBEI LONGXIANG PHARMA TECH CO LTD
Publication Date
2014-04-02

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Abstract

The invention discloses a toltrazuril potassium salt soluble powder and a preparation method thereof. The toltrazuril potassium salt soluble powder is prepared from the following raw materials by mass percent: 2.5-50% of toltrazuril potassium salt, 1-20% of a pH regulator, 0.1-3% of an anti-caking agent and 27-96.4% of a water soluble diluent. According to the method, a solid dispersion technology is adopted, so that the toltrazuril potassium salt can be well dispersed in solid dispersion carrier formed by the water soluble diluent, the pH regulator and the anti-caking agent, and the toltrazuril potassium salt soluble powder can be prepared. The toltrazuril potassium salt soluble powder is soluble in water, high in stability and weak in hygroscopicity. Therefore, the medicine prepared by the soluble powder is soluble in water, high in stability and weak in hygroscopicity, can be used for treating and preventing coccidiosis of animals, and is remarkable in treatment effect and convenient in dosage; furthermore, the dosage of administration can be accurately controlled according to the state of the illness of the animal, so that the coccidiosis of the animals can be rapidly and accurately prevented and treated, and the waste of the medicine in the dosing process can be avoided. The prepared soluble powder is simple in method and low in cost.
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Description

technical field

[0001] The invention relates to a soluble powder of toltrazuril potassium salt, a preparation method and application thereof, and belongs to the field of veterinary preparations. technical background

[0002] Chicken coccidiosis is a chicken parasitic disease caused by Eimeria coccidiosis. Most of them break out in young animals, and the mortality rate is as high as 30%. It is currently the most harmful parasitic disease to the chicken industry. There is no cross-immunity between the various species of Eimeria, and it is easy to break out coccidiosis caused by different species. Rabbit coccidiosis is caused by a variety of coccidia of the genus Eimeria parasitizing in the small intestine or bile duct epithelial cells of rabbits. Rabbits of various breeds and ages can be infected, but rabbits aged 1 to 3 months are the most susceptible and have serious illness and high mortality; A mucohemorrhagic inflammatory disease of the small and large intestines caused...

Claims

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