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Medicine for treating qi-deficiency and blood-stasis type keloid and preparation method thereof

A technology for qi deficiency and blood stasis and keloids, applied in the field of pharmaceutical preparations, can solve the problems of severe scar contracture and dysfunction, unsatisfactory treatment effect, and easy to produce drug dependence, etc., to achieve short treatment period, no toxic side effects, no pain fast effect

Inactive Publication Date: 2015-04-29
王竞鹏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] Disadvantages of Western medicine treatment: Even if the wound heals smoothly, wide and thickened scar tissue will gradually occur in the future; heavy scars, contractures and dysfunctions of varying degrees will occur. In addition, the treatment effect is not very satisfactory, and the cost is expensive. Patients will have side effects, easy to relapse, and prone to drug dependence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0080] When the dosage form of the medicine is powder injection, its preparation method comprises the following steps:

[0081] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixture composed of micron-sized particles with a volume average particle size of 0.1-10 μm and nano-sized particles with a volume-average particle size of less than 0.1 μm Powder, the powder yield of the mixed powder is at least 95%;

[0082] In the second step, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixed powder that is 3 to 5 times the mass of the mixed powder obtained in the first step, stir and dissolve to obtain an ethanol solution, and put the ethanol solution in Stand still for 24-36 hours under the condition of 5°C-10°C, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, concentrate and dry, and put it into a superf...

Embodiment 1

[0095] Embodiment 1 powder injection

[0096] The preparation process of the powder injection of the present invention is as follows: take honeysuckle 200g, 300g jackberry, 170g barberry, 300g dandelion, 240g Guotanlong, 310g Viola chinensis, 220g Touguxiang, 180g Miltonia Spatholobus, 150g Paoshanjia, Geshanjia 260g incense, 300g plantain seed, 350g dragon boat flower root, 200g coix seed, 150g poria cocos, 340g yellow lotus, 140g comfrey, 200g mopancao, 300g red peony root, 170g zoumafeng, 330g lianmoca, clematis 150g, Gardenia 320g, Dilong 150g, Shanzhigen 250g, Jujube 300g, Egg Ginseng 360g, Musk 100g, Vitex 320g, Stephania 150g, Duckweed 330g and Wood Beetle 30g;

[0097] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particle size of 0.7 μm and nano-sized particles with a volume average particle size of less than 0.1 μm ma...

Embodiment 2

[0100] Example 2 ointment

[0101] The preparation process of the ointment of the present invention is as follows: take 150g of honeysuckle, 320g of jackfruit, 200g of berberis, 250g of dandelion, 180g of Guotanlong, 300g of Viola chinensis, 250g of Toguxiang, 300g of Miltonia Spatholobus, 170g of Paoshania, and 170g of Geshanxiang 260g, psyllium 150g, dragon boat flower root 340g, coix seed 200g, poria cocos 220g, yellow lotus 340g, comfrey 220g, mopancao 150g, red peony 300g, zoumafeng 200g, lily 330g, clematis 100g , gardenia 320g, earthworm 120g, mountain branch root 220g, jujube 300g, egg ginseng 360g, musk 160g, vitex 320g, stephenia 140g, duckweed 320g and ground beetle 30g;

[0102] The first step is to mix the raw materials of the drug in proportion, crush them into 50-mesh powder, add ethanol with an alcohol concentration of 85% that is 3 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract The medicinal dregs o...

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Abstract

The invention discloses a medicine for treating qi-deficiency and blood-stasis type keloid and a preparation method thereof. The medicine comprises the following various raw medicinal materials: honeysuckle, philippine flemingia root, berberis thunbergii, dandelion, maidenhair, Chinese violet, radix gaultheria, caulis spatholobi, stir-baked squama manitis, angelica citriodora hance, semen plantaginis, ixora chinensis roots, coix seeds, poria cocos, polygala aureocauda dunn, lithospermum, honewort, radix paeoniae rubra, boea hygrometrica, nepeta glechoma benth, radix clematidis, cape jasmine, earthworm, pittosporum roots, Chinese dates, codonopsis convolvulacea, musk, fructus viticis, stephania japonica, duckweed and ground beeltle. The medicine disclosed by the invention has the beneficial effects of taking dispersing blood stasis, detoxifying and dredging collaterals as a treatment principle, has the effects of dispelling wind and clearing heat, activating blood and promoting menstruation, promoting urination and purging intense heat, and tonifying qi and blood, and is mainly used for treating qi-deficiency and blood-stasis type keloid; the medicine has the advantages of being fast to become effective, high in effective rate, definite in curative effect, short in treatment course, free from toxic and side effects, low in price and the like.

Description

[0001] technical field [0002] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating keloids of Qi deficiency and blood stasis type and a preparation method thereof. Background technique [0003] Keloids, also known as giant scars, scars, connective tissue hyperplasia, meat bumps, and keloids, are the result of collagen synthesis and metabolic function losing normal restraint control and continuing to be in a hyperactive state during the healing process of skin injuries, resulting in excessive proliferation of collagen fibers , also known as connective tissue hyperplasia, is called keloid or giant scar disease in traditional Chinese medicine. It is manifested as a benign lump that protrudes from normal skin, has different shapes, and is red in color and hard. Commonly known as "meat lumps". [0004] The etiology of keloids in traditional Chinese medicine: keloids refer to the excessive hyperplasia and transpar...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P17/02A61K35/62A61K35/64A61K35/55A61K35/36
CPCA61K9/0019A61K9/0053A61K9/06A61K9/08A61K9/19A61K35/36A61K35/55A61K35/62A61K36/076A61K36/11A61K36/185A61K36/23A61K36/28A61K36/288A61K36/29A61K36/30A61K36/344A61K36/355A61K36/45A61K36/48A61K36/486A61K36/53A61K36/59A61K36/65A61K36/68A61K36/69A61K36/71A61K36/716A61K36/725A61K36/74A61K36/744A61K36/85A61K36/86A61K36/88A61K36/8994A61K47/14A61K47/26A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 杨孝良王竞鹏许艳静
Owner 王竞鹏
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