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Pelvic inflammation treating traditional Chinese medicine free-sugar granules

A technology of pelvic inflammatory disease and granules, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc. It can solve the problems of inappropriate use of granules, induce diabetes and children's dental caries, and achieve good palatability and expand the range of suitable consumption Crowd, the effect of high granulation efficiency

Active Publication Date: 2015-07-01
广西壮族自治区花红药业集团股份公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] (3) The scope of application has been expanded: because sucrose has strong biological activity, it can cause gastritis, obesity, diabetes and dental caries in children, so granules are not suitable for sugar-free patients such as diabetes

Method used

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  • Pelvic inflammation treating traditional Chinese medicine free-sugar granules
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] 1) Take a little red 400g, Hedyotis diffusa 200g, peach blossom 400g, white back leaf root 200g, lily 200g, chicken blood vine 300g, myrtle root 400g;

[0033] 2) For the above seven flavors, add water to decoct 3 times, each extraction time is 3 hours, 2 hours, and 1 hour, combine the decoction, filter, and concentrate the filtrate to a clear paste with a relative density of 1.05 when the filtrate is concentrated at 70 °C; Add ethanol to make the alcohol content to be 50%, stir evenly, stand for 24 hours, filter, and recover the extract with a relative density of 1.20 when the ethanol is 70°C;

[0034] 3) After mixing 50g of soluble starch and 20g of macroporous ion exchange resin Amferlite IRC64, put it into the fluidized bed granulation chamber of the spray drying granulator to preheat;

[0035] 4) Add 30 g of soluble starch to water to make a 20% starch solution, add the extract obtained in step 2), stir evenly, add it to a preheated fluidized bed granulation chambe...

Embodiment 2

[0038] 1) Take a little bit of red 600g, Hedyotis diffusa 400g, peach blossom 600g, white back leaf root 400g, lily 400g, chicken blood vine 500g, myrtle root 600g;

[0039] 2) For the above seven flavors, add water and cook for 2 times. The extraction time is 3 hours and 2 hours each time. Combine the decoction and filter. The filtrate is concentrated to a clear paste with a relative density of 1.25 at 80 °C; The alcohol content is 80%, stir well, stand for 24 hours, filter, and the filtrate recovers the extract with a relative density of 1.30 when the ethanol is at 80°C;

[0040] 3) After mixing 70g of soluble starch and 40g of macroporous ion exchange resin Amferlite IRC64, put it into the fluidized bed granulation chamber of the spray drying granulator to preheat;

[0041] 4) Add 50 g of soluble starch to water to make a 30% starch solution, add the extract obtained in step 2), stir evenly, add it to a preheated fluidized bed granulation chamber, and spray dry to obtain gr...

Embodiment 3

[0044] 1) Take a little red 500g, Hedyotis diffusa 300g, peach blossom 500g, white back leaf root 300g, lily 300g, chicken blood vine 400g, myrtle root 500g;

[0045] 2) For the above seven flavors, add water and boil for 2 times, the first time is 2 hours, the second time is 1.5 hours, the decoction is combined, filtered, and the filtrate is concentrated to a clear paste with a relative density of 1.20 at 80 °C; put it at room temperature and then add ethanol Make the alcohol content 65%, stir evenly, stand for 24 hours, filter, and recover the extract with a relative density of 1.25 when ethanol is recovered from the filtrate to 80°C;

[0046] 3) After mixing 60g soluble starch and 30g macroporous ion exchange resin Amferlite IRC64, put it into the fluidized bed granulation chamber of the spray drying granulator to preheat;

[0047] 4) Add 40 g of soluble starch to water to make a 25% starch solution, add the extract obtained in step 2), stir evenly, and spray dry to obtain ...

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Abstract

The present invention relates to pelvic inflammation treating traditional Chinese medicine free-sugar granules and a preparation method thereof. The pelvic inflammation treating traditional Chinese medicine free-sugar granules are prepared from the following raw materials: emilia sonchifolia, hedyotis diffusa willd, urena lobata, mallotus apelta root, thlaspi arvense, kadsura interior and rhodomyrtus tomentosa root. The present invention further provides the preparation method of the pelvic inflammation treating traditional Chinese medicine free-sugar granules. According to the present invention, the spray drying method is used to granulate, such that the auxiliary material consumption is reduced, the taking dose of the patient is low, and the taking and the carrying are convenient; and the soluble starch and the ion exchange resin are adopted as the auxiliary materials so as to improve the viscosity and the fluidity of the traditional Chinese medicine extract, and with the ion exchange resin, the action effect of the drug on the human body can be prolonged, the sweetener consumption can be reduced, and the drug property can be improved.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine sugar-free granule for treating pelvic inflammatory disease and a preparation method thereof. Background technique [0002] Chronic pelvic inflammatory disease (CPID) refers to the chronic inflammation of female reproductive organs, surrounding connective tissue and depleted peritoneum. . The main clinical features are abdominal pain, abnormal vaginal discharge, thickening of pelvic tissue, adhesion and mass formation. Inflammation can be confined to one part or involve several parts at the same time. It often occurs repeatedly and is difficult to heal. It is one of the common causes of ectopic pregnancy and infertility. In recent years, the incidence of chronic pelvic inflammatory disease has been increasing year by year, and it has become a common and frequent gynecological disease. [0003] Western medicine believes tha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61K9/16A61P15/00
Inventor 韦飞燕张艳华陈乃智陆晖邓娟娟
Owner 广西壮族自治区花红药业集团股份公司
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